The rise of DNA methylation and the importance of chromatin on multidrug resistance in cancer. (Q35563862)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14567978%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

review article

1 reference

title

The rise of DNA methylation and the importance of chromatin on multidrug resistance in cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14567978%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

main subject

DNA methylation

0 references

multiple drug resistance

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14567978%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

author name string

Emma K Baker

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14567978%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

language of work or name

English

0 references

publication date

1 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14567978%20AND%20SRC:MED&resulttype=core&format=json

Experimental Cell Research

20 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14567978%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

volume

290

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14567978%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

issue

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14567978%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

page(s)

177-194

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14567978%20AND%20SRC:MED&resulttype=core&format=json

Clinical multidrug resistance in cancer: a multifactorial problem

20 December 2019

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Binding of the Sp1 transcription factor by the human Harvey ras1 proto-oncogene promoter

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A conserved sequence in the T-cell receptor beta-chain promoter region

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Mechanism of transcriptional activation by Sp1: evidence for coactivators

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A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation

7 January 2021

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Increased expression and DNA-binding activity of transcription factor Sp1 in doxorubicin-resistant HL-60 leukemia cells

7 January 2021

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DNA methylation, chromatin structure and regulation of Herpes simplex virus tk gene expression

7 January 2021

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Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene

7 January 2021

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DNA methylation directs a time-dependent repression of transcription initiation

7 January 2021

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How does DNA methylation repress transcription?

7 January 2021

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Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs

7 January 2021

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Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

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MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

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7 January 2021

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Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

7 January 2021

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

7 January 2021

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

7 January 2021

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7 January 2021

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The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation

7 January 2021

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Mechanism of transcriptional regulation by methyl-CpG binding protein MBD1

7 January 2021

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7 January 2021

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7 January 2021

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5-Methylcytosine localised in mammalian constitutive heterochromatin.

7 January 2021

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7 January 2021

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7 January 2021

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Dnmt3L is a transcriptional repressor that recruits histone deacetylase

7 January 2021

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7 January 2021

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A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

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7 January 2021

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Active demethylation of the paternal genome in the mouse zygote

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7 January 2021

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Evidence that protein binding specifies sites of DNA demethylation

7 January 2021

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Enzymic removal of 5-methylcytosine from DNA by a human DNA-glycosylase

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DNA demethylation in vitro: involvement of RNA.

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Cytosine methylation and mammalian development

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Cancer epigenetics comes of age

7 January 2021

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Gilbert's conjecture: the search for DNA (cytosine-5) demethylases and the emergence of new functions for eukaryotic DNA (cytosine-5) methyltransferases

7 January 2021

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Mechanisms of DNA demethylation in chicken embryos. Purification and properties of a 5-methylcytosine-DNA glycosylase

7 January 2021

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Demethylation of DNA by purified chick embryo 5-methylcytosine-DNA glycosylase requires both protein and RNA.

7 January 2021

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The RNA moiety of chick embryo 5-methylcytosine- DNA glycosylase targets DNA demethylation

7 January 2021

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5-methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex

7 January 2021

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Rapid up-regulation of mdr1 expression by anthracyclines in a classical multidrug-resistant cell line

7 January 2021

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The direct activation of human multidrug resistance gene (MDR1) by anticancer agents

7 January 2021

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Induction of MDR1 gene expression by anthracycline analogues in a human drug resistant leukaemia cell line

7 January 2021

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Up-regulation of P-glycoprotein expression in rat liver cells by acute doxorubicin treatment

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CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

PPARgamma knockdown by engineered transcription factors: exogenous PPARgamma2 but not PPARgamma1 reactivates adipogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Zinc finger proteins as designer transcription factors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Positive and negative regulation of endogenous genes by designed transcription factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Zinc fingers: a novel protein fold for nucleic acid recognition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Biotechnologies and therapeutics: chromatin as a target.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Design and selection of novel Cys2His2 zinc finger proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Metal-dependent folding of a single zinc finger from transcription factor IIIA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Selective inhibition of P-glycoprotein expression in multidrug-resistant tumor cells by a designed transcriptional regulator.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Analysis of zinc fingers optimized via phage display: evaluating the utility of a recognition code

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Krüppel-associated boxes are potent transcriptional repression domains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Silencing of RNA polymerases II and III-dependent transcription by the KRAB protein domain of KOX1, a Krüppel-type zinc finger factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

On the use of DNA methylation inhibitors and the reversal of transcriptional silencing.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Genetic protection of repopulating hematopoietic cells with an improved MDR1-retrovirus allows administration of intensified chemotherapy following stem cell transplantation in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Multidrug resistance 1 gene transfer can confer chemoprotection to human peripheral blood progenitor cells engrafted in immunodeficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Performance- and safety-enhanced lentiviral vectors containing the human interferon-beta scaffold attachment region and the chicken beta-globin insulator

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Overexpression of P-glycoprotein in mammalian tumor cell lines after fractionated X irradiation in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Modulation of P-glycoprotein phosphorylation and drug transport by sodium butyrate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Regulation of P-glycoprotein gene expression in hepatocyte cultures and liver cell lines by a trans-acting transcriptional repressor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Activation of human multidrug resistance-1 gene promoter in response to heat shock stress.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Activation of the human MDR1 gene promoter in differentiated neuroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Modulation of mdr-1 expression by a H-ras oncogene in a human colon carcinoma cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Involvement of protein kinase in environmental stress-induced activation of human multidrug resistance 1 (MDR1) gene promoter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

12-O-tetradecanoylphorbol-13-acetate activation of the MDR1 promoter is mediated by EGR1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

Regulation of the MDR1 gene by transcriptional repressors selected using peptide combinatorial libraries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900342-2

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-4827(03)00342-2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14567978%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference