Shielding the double-edged sword: negative regulation of the innate immune system (Q35575529)

8 August 2017

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title

Shielding the double-edged sword: negative regulation of the innate immune system (English)

1 reference

8 August 2017

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28 March 2024

1 reference

28 March 2024

1

Koichi S. Kobayashi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14597727

28 March 2024

author name string

Richard A. Flavell

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14597727

28 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14597727

28 March 2024

publication date

3 November 2003

1 reference

full work available at URL

8 August 2017

https://jlb.onlinelibrary.wiley.com/doi/pdfdirect/10.1189/jlb.0703321

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14597727

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1189%2Fjlb.0703321

28 March 2024

1 reference

https://academic.oup.com/jleukbio/article-pdf/75/3/428/49655240/jlb0428.pdf

28 March 2024

file format

Portable Document Format

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Journal of Leukocyte Biology

28 March 2024

published in

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8 August 2017

75

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8 August 2017

428-433

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8 August 2017

3

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Innate immunity: the virtues of a nonclonal system of recognition

8 August 2017

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Toll-like receptors: critical proteins linking innate and acquired immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

MyD88, an adapter protein involved in interleukin-1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

IL-1 receptor-associated kinase modulates host responsiveness to endotoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

IRAK: a kinase associated with the interleukin-1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Endotoxemia in human septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

TOLERANCE TO BACTERIAL PYROGENS : I. FACTORS INFLUENCING ITS DEVELOPMENT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Mechanisms of endotoxin tolerance. IV. Specificity of the pyrogenic refractory state during continuous intravenous infusions of endotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

MECHANISMS OF ENDOTOXIN TOLERANCE. II. RELATIONSHIP BETWEEN ENDOTOXIN TOLERANCE AND RETICULOENDOTHELIAL SYSTEM PHAGOCYTIC ACTIVITY IN MAN

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Hyporesponsiveness to lipopolysaccharide alters the composition of NF-kappaB binding to the regulatory regions of inducible nitric oxide synthase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: alterations in IL-1 receptor-associated kinase expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of toll-like receptor 4-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

The innate immune response of the respiratory epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Induction of innate immune responses by Escherichia coli and purified lipopolysaccharide correlate with organ- and cell-specific expression of Toll-like receptors within the human urinary tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

CD14- and Toll-like receptor-dependent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

IRAK-M is a negative regulator of Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

A family of cytokine-inducible inhibitors of signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Structure and function of a new STAT-induced STAT inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

A new protein containing an SH2 domain that inhibits JAK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Regulation of Toll-like receptor 4 signalling by A20 zinc finger protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation

21 January 2018

1 reference

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The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Negative regulation of toll-like receptor-mediated signaling by Tollip

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0703321

Unresponsiveness of MyD88-deficient mice to endotoxin

21 January 2018

12

1 reference

Molecular mechanism in tolerance to lipopolysaccharide

28 March 2024

28

1 reference

Differential cytokine induction by doses of lipopolysaccharide and monophosphoryl lipid A that result in equivalent early endotoxin tolerance

28 March 2024

29

1 reference

Monophosphoryl lipid A as a prophylactic for sepsis and septic shock

28 March 2024

30

1 reference

Pulmonary and hepatic gene expression following cecal ligation and puncture: monophosphoryl lipid A prophylaxis attenuates sepsis-induced cytokine and chemokine expression and neutrophil infiltration

28 March 2024

31

1 reference

Differential regulation of cytokine production in lipopolysaccharide tolerance in mice

28 March 2024

34

1 reference

Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression

28 March 2024

39

1 reference

Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators

28 March 2024

42

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Synergy and cross-tolerance between toll-like receptor (TLR) 2- and TLR4-mediated signaling pathways

28 March 2024

43

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Absence of Toll-like receptor 4 explains endotoxin hyporesponsiveness in human intestinal epithelium

28 March 2024

47

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SOCS-1 participates in negative regulation of LPS responses

28 March 2024

61

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SOCS1/JAB is a negative regulator of LPS-induced macrophage activation

28 March 2024

62

1 reference

Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin

28 March 2024

63

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28 March 2024

Identifiers

DOI

10.1189/JLB.0703321

1 reference

8 August 2017

1 reference