Regulation of TLR signaling and inflammation by SOCS family proteins (Q35630518)

9 August 2017

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title

Regulation of TLR signaling and inflammation by SOCS family proteins (English)

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9 August 2017

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Akihiko Yoshimura

1

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9 August 2017

Hiroyuki Mori Masanobu Ohishi

series ordinal

2

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9 August 2017

Daisuke Aki

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3

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9 August 2017

Toshikatsu Hanada

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4

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9 August 2017

language of work or name

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14 January 2004

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Journal of Leukocyte Biology

9 August 2017

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9 August 2017

75

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9 August 2017

3

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9 August 2017

422-427

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Cytokine receptor signalling

9 August 2017

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https://api.crossref.org/works/10.1189%2FJLB.0403194

Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Negative regulation of cytokine signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Suppressors of cytokine signaling: Relevance to gastrointestinal function and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Structure and function of a new STAT-induced STAT inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

A family of cytokine-inducible inhibitors of signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

A new protein containing an SH2 domain that inhibits JAK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Gigantism in mice lacking suppressor of cytokine signalling-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

A three-dimensional model of Suppressor Of Cytokine Signalling 1 (SOCS-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

JAB/SOCS1/SSI-1 is an interleukin-2-induced inhibitor of IL-2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Suppressor of cytokine signaling 1 regulates IL-15 receptor signaling in CD8+CD44high memory T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor alpha-induced cell death in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

A critical role for Stat3 signaling in immune tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

SOCS3 regulates the plasticity of gp130 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

SOCS3 negatively regulates IL-6 signaling in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Ingested type I interferon: a potential treatment for autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

Suppressor of cytokine signaling 1 attenuates IL-15 receptor signaling in CD8+ thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0403194

21 January 2018

Identifiers

DOI

10.1189/JLB.0403194

1 reference

9 August 2017

1 reference