Activin enhances skin tumourigenesis and malignant progression by inducing a pro-tumourigenic immune cell response (Q35639228)

9 August 2017

Activin enhances skin tumourigenesis and malignant progression by inducing a pro-tumourigenic immune cell response (English)

1 reference

9 August 2017

10

Sabine Werner

1 reference

9 August 2017

Michael Meyer

3

0 references

Wendy Havran

7

object named as

Wendy L Havran

1 reference

9 August 2017

8

Reinhard Dummer

1 reference

9 August 2017

Maria Antsiferova

1

1 reference

9 August 2017

Marcel Huber

2

1 reference

9 August 2017

Aleksandra Piwko-Czuchra

4

1 reference

9 August 2017

Tamara Ramadan

5

1 reference

9 August 2017

Amanda S MacLeod

6

1 reference

9 August 2017

Daniel Hohl

9

1 reference

9 August 2017

language of work or name

English

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publication date

6 December 2011

1 reference

9 August 2017

Nature Communications

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9 August 2017

2

1 reference

9 August 2017

576

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Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

9 August 2017

start time

1 September 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms1585

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cites work

Functions of skin-resident γδ T cells

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The regulation and functions of activin and follistatin in inflammation and immunity.

27 July 2018

1 reference

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Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

IL-7 is essential for homeostatic control of T cell metabolism in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

A role for human skin-resident T cells in wound healing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Activin A induces Langerhans cell differentiation in vitro and in human skin explants

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells

27 July 2018

1 reference

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Cancer as an overhealing wound: an old hypothesis revisited

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Immune surveillance: a balance between protumor and antitumor immunity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Activin A functions as a Th2 cytokine in the promotion of the alternative activation of macrophages

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Dissociation of angiogenesis and tumorigenesis in follistatin- and activin-expressing tumors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Activin signaling and its role in regulation of cell proliferation, apoptosis, and carcinogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Roles of activin in tissue repair, fibrosis, and inflammatory disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Paradoxical roles of the immune system during cancer development

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Langerhans cells are strongly reduced in the skin of transgenic mice overexpressing follistatin in the epidermis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Activin controls skin morphogenesis and wound repair predominantly via stromal cells and in a concentration-dependent manner via keratinocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

The distinct contributions of murine T cell receptor (TCR)gammadelta+ and TCRalphabeta+ T cells to different stages of chemically induced skin cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Resident skin-specific gammadelta T cells provide local, nonredundant regulation of cutaneous inflammation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Activins and inhibins in endocrine and other tumors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Impaired wound healing in transgenic mice overexpressing the activin antagonist follistatin in the epidermis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Regulation of cutaneous malignancy by gammadelta T cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Gamma-delta T cells: immunoregulatory functions and immunoprotection.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

The Ca2+-binding proteins S100A8 and S100A9 are encoded by novel injury-regulated genes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

The N-myc oncogene in human neuroblastoma cells: down-regulation of an angiogenesis inhibitor identified as activin A.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Keratinocyte-derived IL-7 serves as a growth factor for dendritic epidermal T cells in mice.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is expressed in mouse skin in response to tumor-promoting agents and modulates dermal inflammation and epidermal dark cell numbers.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis--thirty-third G. H. A. Clowes Memorial Award Lecture.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Interleukin (IL)-15 promotes the growth of murine epidermal gamma delta T cells by a mechanism involving the beta- and gamma c-chains of the IL-2 receptor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Studies on the mechanisms involved in multistage carcinogenesis in mouse skin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Thy-1+ dendritic epidermal cells express T3 antigen and the T-cell receptor gamma chain.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Origin of Thy-1+ dendritic epidermal cells of adult mice from fetal thymic precursors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

The Immunobiology of T Cells with Invariant gammadelta Antigen Receptors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Overexpression of activin A in oral squamous cell carcinoma: association with poor prognosis and tumor progression

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Activin a promotes the TGF-beta-induced conversion of CD4+CD25- T cells into Foxp3+ induced regulatory T cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Activin-A attenuates several human natural killer cell functions

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Activin-A: a novel dendritic cell-derived cytokine that potently attenuates CD40 ligand-specific cytokine and chemokine production.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Activin A suppresses neuroblastoma xenograft tumor growth via antimitotic and antiangiogenic mechanisms

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Crucial role of activin a in tubulogenesis of endothelial cells induced by vascular endothelial growth factor

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Clinical significance of the expression of activin A in esophageal carcinoma.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Activin has direct long-range signalling activity and can form a concentration gradient by diffusion.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Role of the epidermal growth factor receptor and transforming growth factor alpha in mouse skin carcinogenesis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247817

Epidermal γδ T cells sense precancerous cellular dysregulation and initiate immune responses

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS1585

Localized production of TGF-β mRNA in tumour promoter-stimulated mouse epidermis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS1585

Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS1585

Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis

21 January 2018

1 reference

12 December 2020

FACS purification of bone marrow-derived epidermal populations in mice: Langerhans cells and Thy-1+ dendritic cells

1 reference

12 December 2020

Multistage chemical carcinogenesis protocols produce spindle cell carcinomas of the mouse skin

1 reference

12 December 2020

Strong induction of activin expression after injury suggests an important role of activin in wound repair

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS1585

1 reference

9 August 2017

0 references

1 reference

9 August 2017

1 reference