Radiosensitization of human pancreatic cancer cells by MLN4924, an investigational NEDD8-activating enzyme inhibitor (Q35653286)

9 August 2017

title

Radiosensitization of human pancreatic cancer cells by MLN4924, an investigational NEDD8-activating enzyme inhibitor (English)

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9 August 2017

1 reference

Dongping Wei

1

1 reference

9 August 2017

Hua Li

2

1 reference

9 August 2017

Jie Yu

3

1 reference

9 August 2017

Jonathan T Sebolt

4

1 reference

9 August 2017

Lili Zhao

5

1 reference

9 August 2017

Theodore S Lawrence

6

1 reference

9 August 2017

Peter G Smith

7

1 reference

9 August 2017

Meredith A Morgan

8

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9 August 2017

Yi Sun

9

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9 August 2017

language of work or name

English

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publication date

9 November 2011

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9 August 2017

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9 August 2017

volume

72

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9 August 2017

issue

1

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9 August 2017

page(s)

282-293

1 reference

Induction of p21-dependent senescence by an NAE inhibitor, MLN4924, as a mechanism of growth suppression

9 August 2017

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NEDD8-targeting drug MLN4924 elicits DNA rereplication by stabilizing Cdt1 in S phase, triggering checkpoint activation, apoptosis, and senescence in cancer cells

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-{kappa}B-dependent lymphoma

25 September 2018

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Targeting NEDD8-activated cullin-RING ligases for the treatment of cancer.

25 September 2018

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Chaotic license for genetic instability and cancer

25 September 2018

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7 December 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22072567

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

SnapShot: F Box Proteins II

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22072567

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-11-2866

1 reference

9 August 2017

1 reference

9 August 2017

1 reference