Combined pharmacophore modeling, docking, and 3D-QSAR studies of PLK1 inhibitors (Q35669467)

9 August 2017

title

Combined pharmacophore modeling, docking, and 3D-QSAR studies of PLK1 inhibitors (English)

1 reference

9 August 2017

Shuai Lu

1

1 reference

9 August 2017

Hai-Chun Liu

2

1 reference

9 August 2017

Ya-Dong Chen

3

1 reference

9 August 2017

Hao-Liang Yuan

4

1 reference

9 August 2017

Shan-Liang Sun

5

1 reference

9 August 2017

Yi-Ping Gao

6

1 reference

9 August 2017

Pei Yang

7

1 reference

9 August 2017

Liang Zhang

8

1 reference

9 August 2017

Tao Lu

9

1 reference

9 August 2017

language of work or name

English

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publication date

1 December 2011

1 reference

International Journal of Molecular Sciences

9 August 2017

published in

1 reference

9 August 2017

volume

12

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9 August 2017

issue

12

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9 August 2017

page(s)

8713-8739

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Creative Commons Attribution 4.0 International

9 August 2017

copyright license

start time

1 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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NMS-P937, a 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivative as potent and selective Polo-like kinase 1 inhibitor

27 July 2018

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Plk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppression

27 July 2018

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4,5-Dihydro-1H-pyrazolo[4,3-h]quinazolines as potent and selective Polo-like kinase 1 (PLK1) inhibitors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257097

Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

27 July 2018

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Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors

27 July 2018

1 reference

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Targeting Polo-like kinase in cancer therapy

27 July 2018

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27 July 2018

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Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells.

27 July 2018

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BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo.

27 July 2018

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27 July 2018

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27 July 2018

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Structure and function of Polo-like kinases

27 July 2018

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Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome

27 July 2018

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Polo-like kinases and centrosome regulation

27 July 2018

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Dominant-negative polo-like kinase 1 induces mitotic catastrophe independent of cdc25C function

27 July 2018

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PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression.

27 July 2018

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Activated polo-like kinase Plx1 is required at multiple points during mitosis in Xenopus laevis

27 July 2018

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Development and validation of a genetic algorithm for flexible docking

27 July 2018

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Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins

27 July 2018

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Identification and validation of a potent type II inhibitor of inactive polo-like kinase 1.

25 September 2018

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Polo-like Kinase 1 Triggers the Initiation of Cytokinesis in Human Cells by Promoting Recruitment of the RhoGEF Ect2 to the Central Spindle

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257097

Targeting polo-like kinase 1 for cancer therapy.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257097

Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257097

Detailed analysis of grid-based molecular docking: A case study of CDOCKER-A CHARMm-based MD docking algorithm.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257097

Polo-like kinase-1 is a target of the DNA damage checkpoint

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FIJMS12128713

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22272100

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Downregulation of human polo-like kinase activity by antisense oligonucleotides induces growth inhibition in cancer cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22272100

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tumor regression by combination antisense therapy against Plk1 and Bcl-2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22272100

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/IJMS12128713

1 reference

9 August 2017

1 reference

9 August 2017

1 reference