High glucose-induced repression of RAR/RXR in cardiomyocytes is mediated through oxidative stress/JNK signaling (Q35672804)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21882190%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

High glucose-induced repression of RAR/RXR in cardiomyocytes is mediated through oxidative stress/JNK signaling (English)

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12 February 2020

1

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12 February 2020

author name string

Rakeshwar S Guleria

2

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12 February 2020

Irina T Nizamutdinova

3

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12 February 2020

Kenneth M Baker

4

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12 February 2020

Jing Pan

5

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12 February 2020

publication date

1 June 2012

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Journal of Cellular Physiology

12 February 2020

published in

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12 February 2020

volume

227

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12 February 2020

issue

6

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12 February 2020

page(s)

2632-2644

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Involvement of RhoA/ROCK in myocardial fibrosis in a rat model of type 2 diabetes

12 February 2020

cites work

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The role of JNK proteins in metabolism

12 July 2018

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Oxidative Stress and Diabetic Complications

12 July 2018

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Retinoic acid receptor‐mediated signaling protects cardiomyocytes from hyperglycemia induced apoptosis: Role of the renin‐angiotensin system

12 July 2018

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Cellular retinol-binding protein type I (CRBP-I) regulates adipogenesis

12 July 2018

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Role of muscle c-Jun NH2-terminal kinase 1 in obesity-induced insulin resistance

12 July 2018

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A coordinated phosphorylation cascade initiated by p38MAPK/MSK1 directs RARalpha to target promoters

12 July 2018

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All-trans retinoic acid inhibits type 1 diabetes by T regulatory (Treg)-dependent suppression of interferon-gamma-producing T-cells without affecting Th17 cells

12 July 2018

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Acute hyperglycemia and oxidative stress: direct cause and effect?

12 July 2018

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12 July 2018

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Protein kinases and the proteasome join in the combinatorial control of transcription by nuclear retinoic acid receptors

12 July 2018

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Cyclin H binding to the RARalpha activation function (AF)-2 domain directs phosphorylation of the AF-1 domain by cyclin-dependent kinase 7.

12 July 2018

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Phosphorylation of the retinoid x receptor at the omega loop, modulates the expression of retinoic-acid-target genes with a promoter context specificity

12 July 2018

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Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes

12 July 2018

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c-Jun N-terminal kinase contributes to aberrant retinoid signaling in lung cancer cells by phosphorylating and inducing proteasomal degradation of retinoic acid receptor alpha

12 July 2018

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Mitogen-activated protein kinases and mitogen-activated protein kinase phosphatases mediate the inhibitory effects of all-trans retinoic acid on the hypertrophic growth of cardiomyocytes

12 July 2018

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Nuclear retinoid receptors and the transcription of retinoid-target genes

12 July 2018

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Nuclear receptors: integration of multiple signalling pathways through phosphorylation

12 July 2018

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A central role for JNK in obesity and insulin resistance

12 July 2018

1 reference

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Phosphorylation by p38MAPK and recruitment of SUG-1 are required for RA-induced RAR gamma degradation and transactivation

12 July 2018

1 reference

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Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes

12 July 2018

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Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RARalpha) and oncogenic RARalpha fusion proteins

12 July 2018

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Mitogen-activated protein kinase inhibits 1,25-dihydroxyvitamin D3-dependent signal transduction by phosphorylating human retinoid X receptor alpha

12 July 2018

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Oxidative stress induces DNA fragmentation and caspase activation via the c-Jun NH2-terminal kinase pathway in H9c2 cardiac muscle cells.

12 July 2018

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Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats

12 July 2018

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Retinoid receptors in transcriptional regulation

12 July 2018

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Biochemical pathways of retinoid transport, metabolism, and signal transduction

12 July 2018

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1,25(OH)2 vitamin D3, and retinoic acid antagonize endothelin-stimulated hypertrophy of neonatal rat cardiac myocytes

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Role of oxidative stress in development of complications in diabetes

12 July 2018

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c-Jun N-terminal kinase activation by oxidative stress suppresses retinoid signaling through proteasomal degradation of retinoic acid receptor α protein in hepatic cells

12 July 2018

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High glucose induces apoptosis in AC16 human cardiomyocytes via macrophage migration inhibitory factor and c-Jun N-terminal kinase

25 September 2018

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Dominant-negative p38alpha mitogen-activated protein kinase prevents cardiac apoptosis and remodeling after streptozotocin-induced diabetes mellitus

25 September 2018

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All-trans retinoic acid prevents development of cardiac remodeling in aortic banded rats by inhibiting the renin-angiotensin system

25 September 2018

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All-trans retinoic acid prevents angiotensin II- and mechanical stretch-induced reactive oxygen species generation and cardiomyocyte apoptosis

25 September 2018

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Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes.

25 September 2018

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Antioxidant treatment attenuates hyperglycemia-induced cardiomyocyte death in rats

25 September 2018

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Dominant negative 14-3-3 promotes cardiomyocyte apoptosis in early stage of type I diabetes mellitus through activation of JNK.

25 September 2018

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Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response

25 September 2018

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Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure

25 September 2018

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Effects of all-trans retinoic acid on angiotensin II-induced myocyte hypertrophy

25 September 2018

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Vitamin A, retinol binding protein and lipids in type 1 diabetes mellitus

25 September 2018

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Phosphorylation of retinoid X receptor alpha at serine 260 impairs its metabolism and function in human hepatocellular carcinoma

25 September 2018

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25 September 2018

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Stress pathway activation induces phosphorylation of retinoid X receptor

25 September 2018

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12 December 2020

Diabetic cardiomyopathy

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12 December 2020

Quantification of physiological levels of retinoic acid

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12 December 2020

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12 December 2020

Serum vitamin A and retinol-binding protein in patients with insulin-dependent diabetes mellitus

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12 December 2020

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12 December 2020

Streptozotocin-induced diabetes in rats is associated with impaired metabolic availability of vitamin A (retinol)

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12 December 2020

Stimulation of RAR alpha activation function AF-1 through binding to the general transcription factor TFIIH and phosphorylation by CDK7

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12 December 2020

Stimulation of "stress-regulated" mitogen-activated protein kinases (stress-activated protein kinases/c-Jun N-terminal kinases and p38-mitogen-activated protein kinases) in perfused rat hearts by oxidative and other stresses

1 reference

12 December 2020

Mechanical stretch activates the JAK/STAT pathway in rat cardiomyocytes

1 reference

12 December 2020

Hyperphosphorylation of the retinoid X receptor alpha by activated c-Jun NH2-terminal kinases

1 reference

12 December 2020

Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy

1 reference

12 December 2020

Association of a polymorphism in the promoter of the cellular retinoic acid-binding protein II gene (CRABP2) with increased circulating low-density lipoprotein cholesterol

1 reference

12 December 2020

High glucose promotes the production of collagen types I and III by cardiac fibroblasts through a pathway dependent on extracellular-signal-regulated kinase 1/2

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12 December 2020

The metabolic availability of vitamin A is decreased at the onset of diabetes in BB rats

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12 December 2020

Identifiers

DOI

10.1002/JCP.23005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21882190%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21882190%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

21882190

1 reference