Candidate genes for type 2 diabetes (Q35711997)

9 August 2017

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title

Candidate genes for type 2 diabetes (English)

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9 August 2017

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2

Leif Groop

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9 August 2017

Hemang Parikh

1

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9 August 2017

1 May 2004

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Reviews in Endocrine and Metabolic Disorders

9 August 2017

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9 August 2017

5

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9 August 2017

2

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9 August 2017

151-176

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https://scigraph.springernature.com/pub.10.1023/b:remd.0000021437.46773.26

9 August 2017

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cites work

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

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12 December 2020

A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor

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12 December 2020

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

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12 December 2020

A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance

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12 December 2020

Insulin sensitivity is not affected by mutation of codon 972 of the human IRS-1 gene

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12 December 2020

Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is associated with increased leptin levels in women with type-2 diabetes mellitus

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12 December 2020

Identification of genetic variation in the human hormone-sensitive lipase gene and 5' sequences: homology of 5' sequences with mouse promoter and identification of potential regulatory elements.

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12 December 2020

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

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12 December 2020

The significance of the Trp 64 Arg mutation of the beta3-adrenergic receptor gene in impaired glucose tolerance, non-insulin-dependent diabetes mellitus, and insulin resistance in Japanese subjects

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12 December 2020

Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53).

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12 December 2020

Variant sequences of insulin receptor substrate-1 in patients with noninsulin-dependent diabetes mellitus.

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12 December 2020

Insulin receptor substrate-1 variants in non-insulin-dependent diabetes

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12 December 2020

Beta 3-adrenergic receptor gene polymorphism is not a major genetic determinant of obesity and diabetes in Japanese general population.

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12 December 2020

Calpains play a role in insulin secretion and action

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12 December 2020

Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

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12 December 2020

A combination of human leukocyte antigen DQB1*02 and the tumor necrosis factor alpha promoter G308A polymorphism predisposes to an insulin-deficient phenotype in patients with type 2 diabetes.

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12 December 2020

Time of Onset of Non-Insulin-Dependent Diabetes Mellitus and Genetic Variation in the β3-Adrenergic–Receptor Gene

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12 December 2020

Interaction of the G protein beta 3 subunit T825 allele and the IRS-1 Arg972 variant in type 2 diabetes.

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12 December 2020

Systematic search for single nucleotide polymorphisms in the resistin gene: the absence of evidence for the association of three identified single nucleotide polymorphisms with Japanese type 2 diabetes

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12 December 2020

Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians

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12 December 2020

Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR.

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12 December 2020

The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

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12 December 2020

Beta 3-adrenergic-receptor polymorphism: a genetic marker for visceral fat obesity and the insulin resistance syndrome.

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12 December 2020

Lack of association between genetic variation in the beta3-adrenergic receptor gene and insulin resistance in patients with coronary heart disease.

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12 December 2020

Imprinted and Genotype-specific Expression of Genes at theIDDM2Locus in Pancreas and Leucocytes

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12 December 2020

Polymorphic DNA region adjacent to the 5' end of the human insulin gene

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12 December 2020

A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.

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12 December 2020

The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences.

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12 December 2020

E23K single nucleotide polymorphism in the islet ATP-sensitive potassium channel gene (Kir6.2) contributes as much to the risk of Type II diabetes in Caucasians as the PPARgamma Pro12Ala variant.

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12 December 2020

Susceptible locus for obese type 2 diabetes mellitus in the 5'-flanking region of the tumor necrosis factor-alpha gene

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12 December 2020

Effects of intestinal fatty acid-binding protein gene Ala54Thr polymorphism and beta3-adrenergic receptor gene Trp64Arg polymorphism on insulin resistance and fasting plasma glucose in young to older Japanese men.

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12 December 2020

Association between the P12A and c1431t polymorphisms in the peroxisome proliferator activated receptor gamma (PPAR gamma) gene and type 2 diabetes.

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12 December 2020

Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: no association with NIDDM in while Caucasian subjects or evidence of abnormal function when expressed in vitro

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12 December 2020

TRP64ARG β3-adrenergic receptor and obesity in Mexican Americans

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12 December 2020

Prevalence of variants in candidate genes for type 2 diabetes mellitus in The Netherlands: the Rotterdam study and the Hoorn study

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12 December 2020

The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.

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12 December 2020

Molecular scanning of the glycogen synthase and insulin receptor substrate-1 genes in Japanese subjects with non-insulin-dependent diabetes mellitus

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12 December 2020

Impact of the Peroxisome Proliferator Activated Receptor γ2 Pro12Ala polymorphism on adiposity, lipids and non-insulin-dependent diabetes mellitus

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12 December 2020

Insulin receptor substrate (IRS-1) gene polymorphisms in French NIDDM families

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12 December 2020

Resistin / Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-gamma action in humans

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12 December 2020

Molecular characterization of the human beta 3-adrenergic receptor

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12 December 2020

Genetic variations in calpain-10 gene are not a major factor in the occurrence of type 2 diabetes in Japanese

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12 December 2020

Relationship of the tumor necrosis factor-alpha -308 A/G promoter polymorphism with insulin sensitivity and abdominal fat distribution in Japanese patients with type 2 diabetes mellitus

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12 December 2020

Beta 3-adrenergic receptor gene polymorphism and type 2 diabetes in a Caucasian population

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12 December 2020

Gln27Glu variant of the beta2-adrenergic receptor gene is not associated with obesity and diabetes in Japanese-Americans

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12 December 2020

FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance

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12 December 2020

Trp64Arg polymorphism of the beta3-adrenergic receptor gene in pregnancy: association with mild gestational diabetes mellitus

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12 December 2020

Insulin receptor substrate-1 gene variants in lipoatrophic diabetes mellitus and non-insulin-dependent diabetes mellitus: a study of South African black and white subjects

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12 December 2020

Differential effect of PPARgamma2 variants in the development of type 2 diabetes between native Japanese and Japanese Americans

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12 December 2020

Polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus

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12 December 2020

Polymorphism in the beta(1)-adrenergic receptor gene and hypertension

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12 December 2020

Absence of association between genetic variation of the beta 3-adrenergic receptor and metabolic phenotypes in Oji-Cree

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12 December 2020

Trp64Arg Mutation of ?-Adrenergic Receptor in Essential Hypertension Insulin Resistance and the Adrenergic System

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12 December 2020

Amino acid polymorphisms of the insulin receptor substrate-1 in Japanese noninsulin-dependent diabetes mellitus

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12 December 2020

Genetic variation in the beta 3-adrenergic receptor in Japanese NIDDM patients

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12 December 2020

Polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus in the Russian population

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12 December 2020

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

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12 December 2020

PPARgamma, the ultimate thrifty gene

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12 December 2020

Peroxisome proliferator-activated receptor gamma 2 Pro12Ala gene variant is strongly associated with larger body mass in the Taiwanese.

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12 December 2020

A mutation of the b3-adrenergic receptor is associated with visceral obesity but decreased serum triglyceride

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12 December 2020

Genetic studies of the sulfonylurea receptor gene locus in NIDDM and in morbid obesity among French Caucasians

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12 December 2020

Variants in the calpain-10 gene predispose to insulin resistance and elevated free fatty acid levels

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12 December 2020

The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes

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12 December 2020

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

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12 December 2020

K(IR)6.2 polymorphism predisposes to type 2 diabetes by inducing overactivity of pancreatic beta-cell ATP-sensitive K(+) channels

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12 December 2020

Genomic variation in pancreatic ion channel genes in Japanese type 2 diabetic patients

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12 December 2020

Codon 972 polymorphism of the insulin receptor substrate-1 gene in impaired glucose tolerance and late-onset NIDDM.

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12 December 2020

Genetic studies of polymorphisms in ten non-insulin-dependent diabetes mellitus candidate genes in Tamil Indians from Pondichery.

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12 December 2020

Common variants in the regulatory region of the insulin gene are associated with fasting plasma insulin levels in juvenile obesity

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12 December 2020

Regulation of insulin gene expression by the IDDM associated, insulin locus haplotype

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12 December 2020

Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action

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12 December 2020

Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom

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12 December 2020

The TNF-alpha gene Nco I polymorphism influences the relationship among insulin resistance, percent body fat, and increased serum leptin levels

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12 December 2020

Variants in the sulphonylurea receptor gene: association of the exon 16-3t variant with Type II diabetes mellitus in Dutch Caucasians

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12 December 2020

The stimulation-induced increase in skeletal muscle glycogen synthase content is impaired in carriers of the glycogen synthase XbaI gene polymorphism

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12 December 2020

A new subtype of autosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1.

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12 December 2020

CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma

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12 December 2020

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

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12 December 2020

Amino acid polymorphisms in the ATP-regulatable inward rectifier Kir6.2 and their relationships to glucose- and tolbutamide-induced insulin secretion, the insulin sensitivity index, and NIDDM.

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12 December 2020

Circulating TNF-alpha and leptin levels in offspring of NIDDM patients do not correlate to individual insulin sensitivity

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12 December 2020

No association between the G482S polymorphism of the proliferator-activated receptor-gamma coactivator-1 (PGC-1) gene and Type II diabetes in French Caucasians

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12 December 2020

Beta(2)-adrenergic receptor gene variation and hypertension in subjects with type 2 diabetes

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12 December 2020

The UCSNP44 variation of calpain 10 gene on NIDDM1 locus and its impact on plasma glucose levels in type 2 diabetic patients

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12 December 2020

Polymorphism in the 5′ Flanking Region of the Human Insulin Gene: A Genetic Marker for Non-Insulin-Dependent Diabetes

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12 December 2020

Significance of Pro12Ala mutation in peroxisome proliferator-activated receptor-gamma2 in Korean diabetic and obese subjects

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12 December 2020

Genetic variation in the beta3-adrenergic receptor in Japanese NIDDM patients

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12 December 2020

Decreased expression and function of adipocyte hormone-sensitive lipase in subcutaneous fat cells of obese subjects

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12 December 2020

Insulin response to glucose is lower in individuals homozygous for the Arg 64 variant of the beta-3-adrenergic receptor.

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12 December 2020

The insulin gene variable number tandem repeat class I/III polymorphism is in linkage disequilibrium with birth weight but not Type 2 diabetes in the Pima population

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12 December 2020

Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) gene in relation to insulin sensitivity among glucose tolerant caucasians

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12 December 2020

The highly polymorphic region near the human insulin gene is composed of simple tandemly repeating sequences.

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12 December 2020

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

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12 December 2020

A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome

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12 December 2020

Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24.

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12 December 2020

The Trp64Arg Polymorphism of the 3-Adrenergic Receptor Gene: Lack of association with NIDDM and features of insulin resistance syndrome

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12 December 2020

Impact of the Xba1-polymorphism of the human muscle glycogen synthase gene on parameters of the insulin resistance syndrome in a Danish twin population.

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12 December 2020

Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes

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12 December 2020

Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus

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12 December 2020

Isolation and characterization of the human muscle glycogen synthase gene

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12 December 2020

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

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12 December 2020

Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.

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12 December 2020

The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity

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12 December 2020

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

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12 December 2020

The Trp64Arg polymorphism of the β3-adrenergic receptor gene and obesity in Chinese subjects with components of the metabolic syndrome

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12 December 2020

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

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12 December 2020

Effect of the peroxisome proliferator-activated receptor-gamma 2 pro(12)ala variant on obesity, glucose homeostasis, and blood pressure in members of familial type 2 diabetic kindreds

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12 December 2020

TNF‐α polymorphisms and type 2 diabetes mellitus in Taiwanese patients

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12 December 2020

Insulin resistance and type 2 diabetes are not related to resistin expression in human fat cells or skeletal muscle

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12 December 2020

The FOXC2 -512C>T variant is associated with hypertriglyceridaemia and increased serum C-peptide in Danish Caucasian glucose-tolerant subjects

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12 December 2020

Human resistin gene, obesity, and type 2 diabetes: mutation analysis and population study

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12 December 2020

Role of AMP-activated protein kinase in mechanism of metformin action

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12 December 2020

Association of the PRO12ALA polymorphism of the PPAR-gamma2 gene with oxidized low-density lipoprotein and cardiolipin autoantibodies in nondiabetic and type 2 diabetic subjects

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12 December 2020

The exon 16-3t variant of the sulphonylurea receptor gene is not a risk factor for Type II diabetes mellitus in the Dutch Breda cohort

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12 December 2020

Sequence variants in the pancreatic islet beta-cell inwardly rectifying K+ channel Kir6.2 (Bir) gene: identification and lack of role in Caucasian patients with NIDDM

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12 December 2020

Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus

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12 December 2020

Calpain 10 gene polymorphisms are related, not to type 2 diabetes, but to increased serum cholesterol in Japanese

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12 December 2020

Significance of beta2-adrenergic receptor gene polymorphism in obesity and type 2 diabetes mellitus in Korean subjects

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12 December 2020

Studies of the synergistic effect of the Trp/Arg64 polymorphism of the beta3-adrenergic receptor gene and the -3826 A-->G variant of the uncoupling protein-1 gene on features of obesity and insulin resistance in a population-based sample of 379 youn

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12 December 2020

A paired-sibling analysis of the XbaI polymorphism in the muscle glycogen synthase gene

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12 December 2020

Different regulation of free fatty acid levels and glucose oxidation by the Trp64Arg polymorphism of the beta3-adrenergic receptor gene and the promoter variant (A-3826G) of the uncoupling protein 1 gene in familial combined hyperlipidemia.

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12 December 2020

Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles

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12 December 2020

Study of the Trp64Arg polymorphism of the beta3-adrenergic receptor in Greek women with gestational diabetes.

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12 December 2020

The hormone resistin links obesity to diabetes

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12 December 2020

A paired sibling analysis of the beta-3 adrenergic receptor and obesity in Mexican Americans

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12 December 2020

Homozygous combination of calpain 10 gene haplotypes is associated with type 2 diabetes mellitus in a Polish population

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12 December 2020

Codon 972 polymorphism in the insulin receptor substrate-1 gene, obesity, and risk of noninsulin-dependent diabetes mellitus

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12 December 2020

Global and societal implications of the diabetes epidemic

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12 December 2020

Association of the glycogen synthase locus on 19q13 with NIDDM in Pima Indians

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12 December 2020

Association of Trp64Arg polymorphism of the beta3-adrenergic receptor gene and no association of Gln223Arg polymorphism of the leptin receptor gene in Japanese schoolchildren with obesity

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12 December 2020

The risk of obesity and the Trp64Arg polymorphism of the beta(3)-adrenergic receptor: effect modification by age.

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12 December 2020

The beta(3)-adrenergic receptor TRP64ARG polymorphism and obesity in Alaskan Eskimos

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12 December 2020

Insulin sensitivity and body weight changes in young white carriers of the codon 64 amino acid polymorphism of the beta 3-adrenergic receptor gene.

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12 December 2020

Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1.

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12 December 2020

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

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12 December 2020

Genotype Arg/Arg, but not Trp/Arg, of the Trp64Arg polymorphism of the beta(3)-adrenergic receptor is associated with type 2 diabetes and obesity in a large Japanese sample

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12 December 2020

Dominantly inherited hyperinsulinism caused by a mutation in the sulfonylurea receptor type 1.

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12 December 2020

Lack of IRS-1 codon 513 and 972 polymorphism in Pima Indians

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12 December 2020

Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population.

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12 December 2020

Molecular scanning of the insulin receptor substrate-1 (IRS-1) gene in Japanese patients with NIDDM: identification of five novel polymorphisms

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12 December 2020

A promoter genotype and oxidative stress potentially link resistin to human insulin resistance

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12 December 2020

Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion

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12 December 2020

Pro12Ala missense mutation of the peroxisome proliferator activated receptor gamma and diabetes mellitus

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12 December 2020

Polymorphism of the beta3-adrenergic receptor gene affects basal metabolic rate in obese Finns.

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12 December 2020

5' flanking variants of resistin are associated with obesity

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12 December 2020

Beta(3)-adrenergic receptor gene variant is associated with upper body obesity only in obese Japanese-American men but not in women

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12 December 2020

The Trp64Arg mutation of the adrenergic beta-3 receptor gene impairs insulin secretion: a twin study

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12 December 2020

A novel serum protein similar to C1q, produced exclusively in adipocytes

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12 December 2020

Type 2 diabetes and three calpain-10 gene polymorphisms in Samoans: no evidence of association

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12 December 2020

Variation in three single nucleotide polymorphisms in the calpain-10 gene not associated with type 2 diabetes in a large Finnish cohort

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12 December 2020

Testing for population subdivision and association in four case-control studies

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12 December 2020

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

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12 December 2020

The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes

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12 December 2020

Adiponectin and development of type 2 diabetes in the Pima Indian population

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12 December 2020

Association of sets of alleles of genes encoding beta3-adrenoreceptor, uncoupling protein 1 and lipoprotein lipase with increased risk of metabolic complications in obesity

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12 December 2020

UKPDS 19: Heterogeneity in NIDDM: separate contributions of IRS-1 and b3-adrenergic-receptor mutations to insulin resistance and obesity respectively with no evidence for glycogen synthase gene mutations

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12 December 2020

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

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12 December 2020

The W64R variant of the beta3-adrenergic receptor is not associated with type II diabetes or obesity in a large Finnish sample.

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12 December 2020

Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis.

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12 December 2020

Frequency of and interaction between polymorphisms in the beta3-adrenergic receptor and in uncoupling proteins 1 and 2 and obesity in Germans

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12 December 2020

Human resistin gene: molecular scanning and evaluation of association with insulin sensitivity and type 2 diabetes in Caucasians

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12 December 2020

Detection of an amino acid polymorphism in hormone-sensitive lipase in Japanese subjects

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12 December 2020

Association of a polymorphism in the beta 3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns.

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12 December 2020

The association between Trp64Arg polymorphism of the beta3-adrenergic receptor and autonomic nervous system activity

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12 December 2020

Tumour necrosis factor-alpha promoter gene polymorphism at - 308 (genotype AA) in Chinese subjects with Type 2 diabetes

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12 December 2020

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

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12 December 2020

Genetic variants at the resistin locus and risk of type 2 diabetes in Caucasians

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12 December 2020

Peroxisome proliferator-activated receptor-gamma2 P12A and type 2 diabetes in Canadian Oji-Cree

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12 December 2020

FOXC2 mRNA Expression and a 5' untranslated region polymorphism of the gene are associated with insulin resistance.

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12 December 2020

SNP43 of CAPN10 and the risk of type 2 Diabetes in African-Americans: the Atherosclerosis Risk in Communities Study

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12 December 2020

Common variants in the beta2-(Gln27Glu) and beta3-(Trp64Arg)--adrenoceptor genes are associated with elevated serum NEFA concentrations and type II diabetes

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12 December 2020

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

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12 December 2020

Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"?

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12 December 2020

Non-insulin-dependent diabetes mellitus--a collision between thrifty genes and an affluent society

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12 December 2020

Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): a meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians

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12 December 2020

Sequence variants in the sulfonylurea receptor (SUR) gene are associated with NIDDM in Caucasians

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12 December 2020

Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy

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12 December 2020

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

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12 December 2020

Restriction Fragment Length Polymorphism of the Insulin Gene in Diabetes Mellitus

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12 December 2020

Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1.

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12 December 2020

Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus

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12 December 2020

The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes

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12 December 2020

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

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12 December 2020

An ATG repeat in the 3'-untranslated region of the human resistin gene is associated with a decreased risk of insulin resistance.

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12 December 2020

Beta 3-adrenoreceptor gene polymorphism and leptin. Lack of relationship in type 2 diabetic patients.

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12 December 2020

Molecular biology of adenosine triphosphate-sensitive potassium channels

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12 December 2020

Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene

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12 December 2020

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

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12 December 2020

Variants of the insulin receptor substrate-1 and fatty acid binding protein 2 genes and the risk of type 2 diabetes, obesity, and hyperinsulinemia in African-Americans: the Atherosclerosis Risk in Communities Study

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12 December 2020

The Trp64Arg mutation of the beta3 adrenergic receptor gene has no effect on obesity phenotypes in the Québec Family Study and Swedish Obese Subjects cohorts

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12 December 2020

Systematic search for single nucleotide polymorphisms in the FOXC2 gene: the absence of evidence for the association of three frequent single nucleotide polymorphisms and four common haplotypes with Japanese type 2 diabetes

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12 December 2020

A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans

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12 December 2020

Association of polymorphisms in the beta2-adrenergic receptor gene with obesity, hypertriglyceridaemia, and diabetes mellitus

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12 December 2020

Phenotypic characterization of the Trp64Arg polymorphism in the beta 3-adrenergic receptor gene in normal weight and obese subjects.

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12 December 2020

Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility

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12 December 2020

Haplotype combinations of calpain 10 gene polymorphisms associate with increased risk of impaired glucose tolerance and type 2 diabetes in South Indians

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12 December 2020

Prevalence of the Trp64Arg missense mutation of the beta3-adrenergic receptor gene in Japanese subjects.

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12 December 2020

Effects of Trp64Arg mutation in the beta 3-adrenergic receptor gene on weight loss, body fat distribution, glycemic control, and insulin resistance in obese type 2 diabetic patients

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12 December 2020

The insulin gene VNTR, type 2 diabetes and birth weight

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12 December 2020

Association between polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus.

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12 December 2020

Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele

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12 December 2020

The Pro12 -->Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin secretion in individuals with type 2 diabetes

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12 December 2020

β3-adrenergic-receptor allele distributions in children, adolescents and young adults with obesity, underweight or anorexia nervosa

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12 December 2020

Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes

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12 December 2020

Screening for variants of the uncoupling protein 2 gene in Japanese patients with non-insulin-dependent diabetes mellitus

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12 December 2020

The K121Q polymorphism of the PC-1 gene is associated with insulin resistance but not with dyslipidemia

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12 December 2020

No Association Between The Gly971 Arg Variant of the Insulin Receptor Substrate 1 Gene and NIDDM in the Taiwanese Population

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12 December 2020

Resistin gene expression in human adipocytes is not related to insulin resistance.

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12 December 2020

Association of the tumour necrosis factor alpha -308G/A polymorphism with the risk of diabetes in an elderly population-based cohort

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12 December 2020

Association of Trp64Arg mutation of the beta3-adrenergic-receptor with NIDDM and body weight gain

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12 December 2020

Lack of associations between serum leptin, a polymorphism in the gene for the beta 3-adrenergic receptor and glucose tolerance in the Dutch population.

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12 December 2020

Tumor necrosis factor-alpha-238 and -308 polymorphisms do not associated with traits related to obesity and insulin resistance.

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12 December 2020

Tumor necrosis factor alpha gene G-308A polymorphism in the metabolic syndrome

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12 December 2020

Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity

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12 December 2020

A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance

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12 December 2020

A mutation in the beta 3-adrenergic receptor gene is associated with obesity and hyperinsulinemia in Japanese subjects.

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12 December 2020

Mutation of beta 3-adrenergic-receptor gene and response to treatment of obesity

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12 December 2020

Obesity associated with a mutation in a genetic regulator of adipocyte differentiation

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12 December 2020

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

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12 December 2020

Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease

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12 December 2020

The Arg16Gly polymorphism of human beta2-adrenoreceptor is associated with type 2 diabetes in Taiwanese people

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12 December 2020

Linkage Between Markers in the Vicinity of the Uncoupling Protein 2 Gene and Resting Metabolic Rate in Humans

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12 December 2020

Paternal transmission of the very common class I INS VNTR alleles predisposes to childhood obesity

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12 December 2020

Thiazolidinediones (PPARgamma agonists) but not PPARalpha agonists increase IRS-2 gene expression in 3T3-L1 and human adipocytes

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12 December 2020

Meta-analysis of the association of Trp64Arg polymorphism of beta 3-adrenergic receptor gene with body mass index.

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12 December 2020

Mutation screening of the human UCP 2 gene in normoglycemic and NIDDM morbidly obese patients: lack of association between new UCP 2 polymorphisms and obesity in French Caucasians.

1 reference

12 December 2020

Molecular scanning for mutations in the beta 3-adrenergic receptor gene in Nauruans with obesity and noninsulin-dependent diabetes mellitus

1 reference

12 December 2020

Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians

1 reference

12 December 2020

Association of Trp64Arg mutation of the beta 3-adrenergic receptor gene with NIDDM, current and maximal body mass index

1 reference

12 December 2020

The Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort.

1 reference

12 December 2020

Assignment of the gene encoding glycogen synthase (GYS) to human chromosome 19, band q13.3.

1 reference

12 December 2020

Molecular screening of uncoupling protein 2 gene in patients with noninsulin-dependent diabetes mellitus or obesity

1 reference

12 December 2020

Lack of association between the Trp64 Arg mutation in the beta 3-adrenergic receptor gene and obesity in Japanese men: a longitudinal analysis

1 reference

12 December 2020

Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Mexican Americans with Type 2 diabetes mellitus

1 reference

12 December 2020

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

1 reference

12 December 2020

10.1023/B:REMD.0000021437.46773.26

Identifiers

DOI

1 reference

PubMed ID

15041791

Dimensions Publication ID

9 August 2017

0 references

1 reference

PubMed ID

15041791