NF-kappaB2 is required for the control of autoimmunity by regulating the development of medullary thymic epithelial cells (Q35740901)

10 August 2017

NF-kappaB2 is required for the control of autoimmunity by regulating the development of medullary thymic epithelial cells (English)

1 reference

10 August 2017

Baochun Zhang

1

0 references

Pärt Peterson

object named as

Pärt Peterson

4

0 references

author name string

Zhe Wang

2

1 reference

10 August 2017

Jane Ding

3

1 reference

10 August 2017

William T Gunning

5

1 reference

10 August 2017

Han-Fei Ding

6

1 reference

10 August 2017

language of work or name

English

0 references

publication date

17 October 2006

1 reference

Journal of Biological Chemistry

10 August 2017

1 reference

10 August 2017

281

1 reference

10 August 2017

50

1 reference

10 August 2017

38617-38624

1 reference

Central tolerance: learning self-control in the thymus

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Gene targeting of VEGF-A in thymus epithelium disrupts thymus blood vessel architecture

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Dependence of self-tolerance on TRAF6-directed development of thymic stroma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Self-representation in the thymus: an extended view

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Lymphotoxin pathway directs thymic Aire expression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Negative selection--clearing out the bad apples from the T-cell repertoire

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

An essential role for Scurfin in CD4+CD25+ T regulatory cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Control of regulatory T cell development by the transcription factor Foxp3

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

NF-kappa B2 p100 is a pro-apoptotic protein with anti-oncogenic function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Projection of an immunological self shadow within the thymus by the aire protein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

CD40 regulates the processing of NF-kappaB2 p100 to p52

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

RelB cellular regulation and transcriptional activity are regulated by p100.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Requirement for NF-kappaB in osteoclast and B-cell development

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Positional cloning of the APECED gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

CD28/B7 system of T cell costimulation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Medullary thymic epithelium expresses a ligand for CTLA4 in situ and in vitro.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Expression of relB is required for the development of thymic medulla and dendritic cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Lymphocytes selected in allogeneic thymic epithelium mediate dominant tolerance toward tissue grafts of the thymic epithelium haplotype

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Tolerance induced by thymic epithelial grafts in birds

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

In vivo administration of monoclonal antibodies to the CD3 T cell receptor complex induces cell death (apoptosis) in immature thymocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Tolerance induction by thymic medullary epithelium

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847381

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.

27 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

Linking signalling pathways, thymic stroma integrity and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

NF-kappaB signaling. Many roads lead to madrid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

Two pathways to NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

Regulatory T cells and mechanisms of immune system control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

Natural regulatory T cells and self-tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

Formation of a functional thymus initiated by a postnatal epithelial progenitor cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

Functional evidence for a single endodermal origin for the thymic epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606705200

Clonal deletion of V beta 5+ T cells by transgenic I-E restricted to thymic medullary epithelium

21 January 2018

1 reference

12 December 2020

B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of V beta 5+ thymocytes

1 reference

12 December 2020

Constitutive and inducible Rel/NF-kappa B activities in mouse thymus and spleen

1 reference

12 December 2020

RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse

1 reference

12 December 2020

Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL-/- mice

1 reference

12 December 2020

Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice

1 reference

12 December 2020

Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-tolerance

1 reference

12 December 2020

Epithelial heterogeneity in the murine thymus: fucose-specific lectins bind medullary epithelial cells

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M606705200

1 reference

10 August 2017

1 reference

10 August 2017

1 reference