Caspase activation - stepping on the gas or releasing the brakes? Lessons from humans and flies (Q35743108)

10 August 2017

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title

Caspase activation - stepping on the gas or releasing the brakes? Lessons from humans and flies (English)

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10 August 2017

Guy S Salvesen

1

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PubMed ID

15077141

10 August 2017

John M Abrams

series ordinal

2

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PubMed ID

15077141

10 August 2017

language of work or name

English

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publication date

1 April 2004

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10 August 2017

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10 August 2017

23

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10 August 2017

16

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10 August 2017

2774-2784

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207522

10 August 2017

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cites work

Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

Apoptotic activity of REAPER is distinct from signaling by the tumor necrosis factor receptor 1 death domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

Human caspase-7 activity and regulation by its N-terminal peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

The role of cytochrome c in caspase activation in Drosophila melanogaster cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

Characterization of the Drosophila caspase, DAMM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for Eiger signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

Continual low-level activation of the classical complement pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

The Drosophila DIAP1 protein is required to prevent accumulation of a continuously generated, processed form of the apical caspase DRONC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

An essential role for the caspase dronc in developmentally programmed cell death in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

A novel Apaf-1-independent putative caspase-2 activation complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

The inhibitor of apoptosis protein-binding domain of Smac is not essential for its proapoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

IAP proteins: blocking the road to death's door

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

A structural view of mitochondria-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

Caspase-9 can be activated without proteolytic processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

Altered cytochrome c display precedes apoptotic cell death in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

Inhibition of reaper-induced apoptosis by interaction with inhibitor of apoptosis proteins (IAPs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

The role of ARK in stress-induced apoptosis in Drosophila cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

Inhibition of ICE slows ALS in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

Competition and compensation: coupled to death in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Dimeric procaspase-3 unfolds via a four-state equilibrium process

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Molecular cloning of the interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Structural basis of caspase-7 inhibition by XIAP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Activation of the NF-kappaB pathway by caspase 8 and its homologs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Hormone-dependent transactivation by estrogen receptor chimeras that do not interact with hsp90. Evidence for transcriptional repressors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

DRONC, an ecdysone-inducible Drosophila caspase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

DECAY, a novel Drosophila caspase related to mammalian caspase-3 and caspase-7.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Insights into programmed cell death through structural biology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

A matter of life and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

The immune response of Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Structural Basis of Caspase Inhibition by XIAP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Alterations in the apoptotic machinery and their potential role in anticancer drug resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Eiger and its receptor, Wengen, comprise a TNF-like system in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

1 reference

7 January 2021

The Drosophila immune defense against gram-negative infection requires the death protein dFADD.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Removal of the pro-domain does not affect the conformation of the procaspase-3 dimer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Social controls on cell survival and cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Structural basis for the activation of human procaspase-7

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Structural basis for the inhibition of caspase-3 by XIAP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Caspases: intracellular signaling by proteolysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Death in the balance: alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Genetic control of programmed cell death in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Structural basis of IAP recognition by Smac/DIABLO

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207522

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207522

1 reference

10 August 2017

1 reference

PubMed ID

15077141