Signaling control of mRNA translation in cancer pathogenesis (Q35750101)

10 August 2017

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title

Signaling control of mRNA translation in cancer pathogenesis (English)

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10 August 2017

3

Pier Paolo Pandolfi

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Nahum Sonenberg

series ordinal

2

object named as

Nahum Sonenberg

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10 August 2017

Eric C Holland

1

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PubMed ID

15094763

10 August 2017

George Thomas

series ordinal

4

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PubMed ID

15094763

10 August 2017

language of work or name

English

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publication date

1 April 2004

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10 August 2017

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10 August 2017

23

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10 August 2017

18

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10 August 2017

3138-3144

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207590

10 August 2017

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cites work

The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

PTEN function in mammalian cell size regulation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

eIF4E expression in tumors: its possible role in progression of malignancies

21 January 2018

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Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Mutation and expression analysis of the putative prostate tumour-suppressor gene PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Molecular mechanisms of translation initiation in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

The modular phosphorylation and activation of p70s6k.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Rapamycin blocks cell cycle progression of activated T cells prior to events characteristic of the middle to late G1 phase of the cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Multiple phosphorylation of ribosomal protein S6 during transition of quiescent 3T3 cells into early G1, and cellular compartmentalization of the phosphate donor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

The role of the 5' untranslated region of an mRNA in translation regulation during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

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7 January 2021

Mammalian TOR: a homeostatic ATP sensor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Impaired Fas response and autoimmunity in Pten+/- mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

The multiple roles of PTEN in tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Regulation of translation initiation by FRAP/mTOR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Drosophila S6 kinase: a regulator of cell size

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Phosphorylation and activation of p70s6k by PDK1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Signaling networks: the origins of cellular multitasking

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Autophagy and other vacuolar protein degradation mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207590

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207590

1 reference

10 August 2017

1 reference

PubMed ID

15094763