Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells (Q35761917)

10 August 2017

title

Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells (English)

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10 August 2017

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Shengbing Huang

1

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10 August 2017

Frank A Sinicrope

series ordinal

2

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10 August 2017

publication date

2 March 2010

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Molecular Cancer Therapeutics

10 August 2017

published in

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10 August 2017

volume

9

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10 August 2017

issue

3

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10 August 2017

page(s)

742-750

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Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2.

10 August 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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FDA approves sorafenib for patients with inoperable liver cancer

12 July 2018

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The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation

25 September 2018

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25 September 2018

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Activated signal transducer and activator of transcription 3 (STAT3) supports the malignant phenotype of human pancreatic cancer.

25 September 2018

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Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells

25 September 2018

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12 December 2020

Pin1 is required for the Ser727 phosphorylation-dependent Stat3 activity

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12 December 2020

Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells

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12 December 2020

Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis

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12 December 2020

10.1158/1535-7163.MCT-09-1004

Identifiers

DOI

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10 August 2017

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10 August 2017

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