Inhibition of Klebsiella β-Lactamases (SHV-1 and KPC-2) by Avibactam: A Structural Study (Q35764780)

10 August 2017

Inhibition of Klebsiella β-Lactamases (SHV-1 and KPC-2) by Avibactam: A Structural Study (English)

1 reference

10 August 2017

Krisztina M Papp-Wallace

series ordinal

3

object named as

Krisztina M Papp-Wallace

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10 August 2017

4

Robert A Bonomo

1 reference

10 August 2017

Nikhil P Krishnan

1

1 reference

10 August 2017

Nhu Q Nguyen

series ordinal

2

1 reference

10 August 2017

Focco van den Akker

series ordinal

5

1 reference

10 August 2017

language of work or name

English

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publication date

4 September 2015

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10 August 2017

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10 August 2017

10

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10 August 2017

9

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10 August 2017

e0136813

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Creative Commons CC0 License

10 August 2017

start time

4 September 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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cites work

Avibactam and inhibitor-resistant SHV β-lactamases

1 reference

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Variants of β-lactamase KPC-2 that are resistant to inhibition by avibactam

2 October 2017

1 reference

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Molecular basis of selective inhibition and slow reversibility of avibactam against class D carbapenemases: a structure-guided study of OXA-24 and OXA-48

2 October 2017

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Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases

2 October 2017

1 reference

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Kinetics of avibactam inhibition against Class A, C, and D β-lactamases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560403

The ABCD's of β-lactamase nomenclature

2 October 2017

1 reference

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Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC -Lactamases

2 October 2017

1 reference

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Proliferation and significance of clinically relevant β-lactamases

2 October 2017

1 reference

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Design and Exploration of Novel Boronic Acid Inhibitors Reveals Important Interactions with a Clavulanic Acid-Resistant Sulfhydryl-Variable (SHV) β-Lactamase

2 October 2017

1 reference

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Crystal Structure of a Preacylation Complex of the β-Lactamase Inhibitor Sulbactam Bound to a Sulfenamide Bond-Containing Thiol-β-lactamase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560403

Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560403

Current epidemiology and growing resistance of gram-negative pathogens

2 October 2017

1 reference

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NXL104 Irreversibly Inhibits the β-Lactamase from Mycobacterium tuberculosis

2 October 2017

1 reference

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Crystal Structures of KPC-2 -Lactamase in Complex with 3-Nitrophenyl Boronic Acid and the Penam Sulfone PSR-3-226

2 October 2017

1 reference

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Evaluation of ceftazidime and NXL104 in two murine models of infection due to KPC-producing Klebsiella pneumoniae

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560403

Three decades of beta-lactamase inhibitors

2 October 2017

1 reference

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Molecular replacement with MOLREP

2 October 2017

1 reference

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Genetic and Structural Insights into the Dissemination Potential of the Extremely Broad-Spectrum Class A -Lactamase KPC-2 Identified in an Escherichia coli Strain and an Enterobacter cloacae Strain Isolated from the Same Patient in France

2 October 2017

1 reference

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Crystal Structure of KPC-2: Insights into Carbapenemase Activity in Class A β-Lactamases † , ‡

2 October 2017

1 reference

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Rational design of a beta-lactamase inhibitor achieved via stabilization of the trans-enamine intermediate: 1.28 A crystal structure of wt SHV-1 complex with a penam sulfone

2 October 2017

1 reference

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Coot: model-building tools for molecular graphics

2 October 2017

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

2 October 2017

1 reference

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PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

2 October 2017

1 reference

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Tazobactam forms a stoichiometric trans-enamine intermediate in the E166A variant of SHV-1 beta-lactamase: 1.63 A crystal structure

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560403

Inhibition of the SHV-1 beta-lactamase by sulfones: crystallographic observation of two reaction intermediates with tazobactam

2 October 2017

1 reference

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Processing of X-ray diffraction data collected in oscillation mode

2 October 2017

1 reference

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Molecular Mechanism of Avibactam-Mediated β-Lactamase Inhibition

27 July 2018

1 reference

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Activity of ceftaroline-avibactam tested against contemporary Enterobacteriaceae isolates carrying β-lactamases prevalent in the United States.

27 July 2018

1 reference

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Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-Producing Enterobacteriaceae

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560403

In vitro activity of NXL104 in combination with beta-lactams against Klebsiella pneumoniae isolates producing KPC carbapenemases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560403

Emergence of KPC-possessing Klebsiella pneumoniae in Brooklyn, New York: epidemiology and recommendations for detection

27 July 2018

1 reference

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Nitrogen inversion barriers affect the N-oxidation of tertiary alkylamines by cytochromes P450.

27 July 2018

1 reference

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Emergence of serine carbapenemases (KPC and SME) among clinical strains of Enterobacteriaceae isolated in the United States Medical Centers: report from the MYSTIC Program (1999-2005).

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560403

High resolution crystal structures of the trans-enamine intermediates formed by sulbactam and clavulanic acid and E166A SHV-1 {beta}-lactamase

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560403

Inactivation of TEM-1 by Avibactam (NXL-104): Insights from Quantum Mechanics/Molecular Mechanics Metadynamics Simulations

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0136813

10.1371/JOURNAL.PONE.0136813

21 January 2018

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DOI

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10 August 2017

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10 August 2017

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