The Runx genes: lineage-specific oncogenes and tumor suppressors (Q35779743)

10 August 2017

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title

The Runx genes: lineage-specific oncogenes and tumor suppressors (English)

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10 August 2017

Ewan R Cameron

1

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10 August 2017

James C Neil

series ordinal

2

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10 August 2017

language of work or name

English

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publication date

1 May 2004

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10 August 2017

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10 August 2017

volume

23

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10 August 2017

issue

24

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10 August 2017

page(s)

4308-4314

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AML1 amplification in a child with acute lymphoblastic leukemia

10 August 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

Runt and Lozenge function in Drosophila development

21 January 2018

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Alterations of the AML1 transcription factor in human leukemia

21 January 2018

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Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoter

21 January 2018

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Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

21 January 2018

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Genome-based identification of cancer genes by proviral tagging in mouse retrovirus-induced T-cell lymphomas

21 January 2018

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The AML1/ETO fusion protein activates transcription of BCL-2

21 January 2018

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The PEBP2betaMYH11 fusion created by Inv(16)(p13;q22) in myeloid leukemia impairs neutrophil maturation and contributes to granulocytic dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

Altered affinity of CBF beta-SMMHC for Runx1 explains its role in leukemogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

The inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

21 January 2018

1 reference

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Transcriptionally active chimeric gene derived from the fusion of the AML1 gene and a novel gene on chromosome 8 in t(8;21) leukemic cells

21 January 2018

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Cancer risk and low-penetrance susceptibility genes in gene-environment interactions

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

The common retroviral insertion locus Dsi1 maps 30 kilobases upstream of the P1 promoter of the murine Runx3/Cbfa3/Aml2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene

21 January 2018

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til-1: a novel proviral insertion locus for Moloney murine leukaemia virus in lymphomas of CD2-myc transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

Expression of the AML-1 oncogene shortens the G(1) phase of the cell cycle

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

Mechanisms of transcriptional regulation by Runt domain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

The RUNX3 gene--sequence, structure and regulated expression

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

AML1 stimulates G1 to S progression via its transactivation domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

The molecular genetics of cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Runx2: a novel oncogenic effector revealed by in vivo complementation and retroviral tagging

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Chromosome 21 abnormalities with AML1 amplification in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

The Runx genes as dominant oncogenes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

CBF beta-SMMHC, expressed in M4Eo AML, reduced CBF DNA-binding and inhibited the G1 to S cell cycle transition at the restriction point in myeloid and lymphoid cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Runx transcription factors and the developmental balance between cell proliferation and differentiation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Amplification of AML1 in childhood acute lymphoblastic leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

The t(8;21) fusion protein, AML1/ETO, transforms NIH3T3 cells and activates AP-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: a study of 20 cases.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Pattern of malignant disorders in individuals with Down's syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Overexpression of AML1 transcription factor drives thymocytes into the CD8 single-positive lineage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Spectral karyotyping and fluorescence in situ hybridization detect novel chromosomal aberrations, a recurring involvement of chromosome 21 and amplification of the MYC oncogene in acute myeloid leukaemia M2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

ETV6/AML1 fusion by FISH in adult acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Cytoplasmic sequestration of the polyomavirus enhancer binding protein 2 (PEBP2)/core binding factor alpha (CBFalpha) subunit by the leukemia-related PEBP2/CBFbeta-SMMHC fusion protein inhibits PEBP2/CBF-mediated transactivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Genetics of human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

A conserved cysteine residue in the runt homology domain of AML1 is required for the DNA binding ability and the transforming activity on fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

The management of neoplastic disorders of haematopoiesis in children with Down's syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

The common TEL/AML1 rearrangement does not represent a frequent event in acute lymphoblastic leukaemia occuring in children with Down syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

A large variety of alternatively spliced and differentially expressed mRNAs are encoded by the human acute myeloid leukemia gene AML1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Causal relationship between the loss of RUNX3 expression and gastric cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - a model for overcoming inhibition of proliferation by CBF oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Multicolor spectral karyotyping identifies novel translocations in childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

AML1 gene over-expression in childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

High-throughput retroviral tagging to identify components of specific signaling pathways in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

AML1 amplification in a case of childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Amplification of AML1 gene is present in childhood acute lymphoblastic leukemia but not in adult, and is not associated with AML1 gene mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Transcription-coupled translation control of AML1/RUNX1 is mediated by cap- and internal ribosome entry site-dependent mechanisms.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

The expression of SpRunt during sea urchin embryogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Down Syndrome and acute leukaemia: increased risk may be due to trisomy 21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Amplification of the AML1(CBFA2) gene on ring chromosomes in a patient with acute myeloid leukemia and a constitutional ring chromosome 21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

New genes involved in cancer identified by retroviral tagging

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Three distinct domains in TEL-AML1 are required for transcriptional repression of the IL-3 promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Enforced expression of Runx2 perturbs T cell development at a stage coincident with beta-selection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

A full-length Cbfa1 gene product perturbs T-cell development and promotes lymphomagenesis in synergy with myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207130

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207130

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10 August 2017

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