Tumor suppressor activity of RUNX3. (Q35779761)

10 August 2017

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title

Tumor suppressor activity of RUNX3. (English)

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10 August 2017

Suk-Chul Bae

1

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PubMed ID

15156190

10 August 2017

Joong-Kook Choi

series ordinal

2

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PubMed ID

15156190

10 August 2017

language of work or name

English

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publication date

1 May 2004

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10 August 2017

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10 August 2017

23

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10 August 2017

24

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10 August 2017

4336-4340

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207286

10 August 2017

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Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program

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Bcl-xL blocks transforming growth factor-beta 1-induced apoptosis by inhibiting cytochrome c release and not by directly antagonizing Apaf-1-dependent caspase activation in prostate epithelial cells

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A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest

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Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter

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AP-1 and Cbfa/runt physically interact and regulate parathyroid hormone-dependent MMP13 expression in osteoblasts through a new osteoblast-specific element 2/AP-1 composite element

21 January 2018

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Gastric carcinoma: monoclonal epithelial malignant cells expressing Epstein-Barr virus latent infection protein

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RUNX transcription factors as key targets of TGF-beta superfamily signaling

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Genome-based identification of cancer genes by proviral tagging in mouse retrovirus-induced T-cell lymphomas

21 January 2018

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Smads bind directly to the Jun family of AP-1 transcription factors

21 January 2018

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Expression of transcription factor AML-2 (RUNX3, CBF(alpha)-3) is induced by Epstein-Barr virus EBNA-2 and correlates with the B-cell activation phenotype

21 January 2018

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The common retroviral insertion locus Dsi1 maps 30 kilobases upstream of the P1 promoter of the murine Runx3/Cbfa3/Aml2 gene

21 January 2018

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Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene

21 January 2018

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Induction of p53 and Bax during TGF-beta 1 initiated apoptosis in rat liver epithelial cells

21 January 2018

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Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

21 January 2018

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Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis

21 January 2018

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Critical role of Smads and AP-1 complex in transforming growth factor-beta -dependent apoptosis

21 January 2018

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A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

21 January 2018

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cDNA cloning of run, a Caenorhabditis elegans Runt domain encoding gene

21 January 2018

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7 January 2021

Cloning, mapping and expression of PEBP2 alpha C, a third gene encoding the mammalian Runt domain

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7 January 2021

The RUNX3 gene--sequence, structure and regulated expression

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7 January 2021

Epigenomics and epigenetic therapy of cancer

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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

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7 January 2021

The Runx genes as dominant oncogenes

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7 January 2021

A zinc-finger transcription factor induced by TGF-beta promotes apoptotic cell death in epithelial Mv1Lu cells

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7 January 2021

TGF beta/Smad signaling system and its pathologic correlates

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7 January 2021

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

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7 January 2021

Rare occurrence of ras and p53 gene mutations in mouse stomach tumors induced by N-methyl-N-nitrosourea.

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7 January 2021

Mutations truncating the EP300 acetylase in human cancers

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7 January 2021

Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor

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7 January 2021

Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytes

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7 January 2021

Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Cancer epigenetics comes of age

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Hypermethylation of the RUNX3 gene promoter in testicular yolk sac tumor of infants

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7 January 2021

Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

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7 January 2021

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Frequent loss of heterozygosity of the long arm of chromosome 7 is closely associated with progression of human gastric carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Causal relationship between the loss of RUNX3 expression and gastric cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Oncogenic transcription factors in the human acute leukemias

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

RUNX: a trilogy of cancer genes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Expression pattern, regulation, and biological role of runt domain transcription factor, run, in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Estimates of the worldwide incidence of 25 major cancers in 1990.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

The expression of SpRunt during sea urchin embryogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Mechanisms of TGF-beta-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

1 reference

7 January 2021

Three chromosomal rearrangements in neuroblastoma cluster within a 300-kb region on 1p36.1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Promoter methylation status of DAP-kinase and RUNX3 genes in neoplastic and non-neoplastic gastric epithelia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Myc downregulation by transforming growth factor beta required for activation of the p15(Ink4b) G(1) arrest pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Requirement of Runx1/AML1/PEBP2alphaB for the generation of haematopoietic cells from endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207286

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207286

1 reference

10 August 2017

1 reference

PubMed ID

15156190