Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion (Q35794969)

26061564

10 August 2017

title

Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion (English)

1 reference

10 August 2017

4

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13 June 2020

Patrick E. Macdonald

11

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13 June 2020

author name string

Frank Schwede

1

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13 June 2020

Oleg G Chepurny

2

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13 June 2020

Melanie Kaufholz

3

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13 June 2020

Colin A Leech

5

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13 June 2020

Over Cabrera

6

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13 June 2020

Yingmin Zhu

7

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13 June 2020

Fang Mei

8

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13 June 2020

Xiaodong Cheng

9

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13 June 2020

Jocelyn E Manning Fox

10

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13 June 2020

Hans-G Genieser

12

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13 June 2020

Friedrich W Herberg

13

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13 June 2020

George G Holz

14

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publication date

10 June 2015

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26061564

10 August 2017

published in

Molecular Endocrinology

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13 June 2020

volume

29

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issue

7

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13 June 2020

page(s)

988-1005

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New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout mice

13 June 2020

cites work

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Differences in insulin secretion between the rat and mouse: role of cAMP.

12 July 2018

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Novel (Rp)-cAMPS analogs as tools for inhibition of cAMP-kinase in cell culture. Basal cAMP-kinase activity modulates interleukin-1 beta action

12 July 2018

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Stimulation of cloned human glucagon-like peptide 1 receptor expressed in HEK 293 cells induces cAMP-dependent activation of calcium-induced calcium release

12 July 2018

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The pancreatic beta-cell recognition of insulin secretagogues: does cyclic AMP mediate the effect of glucose?

12 July 2018

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12 July 2018

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12 July 2018

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Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

12 July 2018

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Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

12 July 2018

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Relationships Between Fasting Plasma Glucose Levels and Insulin Secretion During Intravenous Glucose Tolerance Tests

12 July 2018

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Dynamics of insulin and cyclic adenosine 3',5'-monophosphate release from the perifused rat islets of langerhans under a slow-rise stimulation with D-glucose and its anomers

12 July 2018

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Insulin release and cyclic AMP accumulation in response to glucose in pancreatic islets of fed and starved rats

12 July 2018

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Enhancement by D2O of glucose-induced cyclic AMP accumulation in rat islets of langerhans

12 July 2018

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Effect of Glucose Adenosine on 3', 5'-Monophosphate Levels in Rat Pancreatic Islets

12 July 2018

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Decreased Cyclic AMP and Insulin Response to Glucose in Isolated Islets of Neonatal Rats

12 July 2018

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Insulin secretion. Interrelationships of glucose, cyclic adenosine 3:5-monophosphate, and calcium

12 July 2018

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Factors governing glucose induced elevation of cyclic 3?5? AMP levels in pancreatic islets

12 July 2018

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Glucose-induced cyclic AMP accumulation in rat islets of langerhans: Preferential effect of the alpha anomer

12 July 2018

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Impaired cAMP generation contributes to defective glucose-stimulated insulin secretion after long-term exposure to palmitate.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

Exchange protein activated by cAMP 1 (Epac1)-deficient mice develop β-cell dysfunction and metabolic syndrome.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

Spatial control of Epac2 activity by cAMP and Ca2+-mediated activation of Ras in pancreatic β cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

Systems analysis of GLP-1 receptor signaling in pancreatic β-cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

cAMP increases the sensitivity of exocytosis to Ca²+ primarily through protein kinase A in mouse pancreatic beta cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

Genetic influences on the insulin response of the beta cell to different secretagogues

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

Insulin exocytosis in Goto-Kakizaki rat beta-cells subjected to long-term glinide or sulfonylurea treatment.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

Novel, isotype-specific sensors for protein kinase A subunit interaction based on bioluminescence resonance energy transfer (BRET).

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

Calcium-induced acrosomal exocytosis requires cAMP acting through a protein kinase A-independent, Epac-mediated pathway

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

Ligand-mediated activation of the cAMP-responsive guanine nucleotide exchange factor Epac

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

Two-photon excitation imaging of pancreatic islets with various fluorescent probes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

Acetoxymethyl esters of phosphates, enhancement of the permeability and potency of cAMP.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484784

Bioreversible protection of nucleoside diphosphates

25 September 2018

1 reference

12 December 2020

Stimulation by D-glucose of cyclic adenosine 3':5'-monophosphate accumulation and insulin release in isolated pancreatic islets of the rat

1 reference

12 December 2020

Cyclic AMP Antagonist Rp-cAMPS Inhibits Amylase Exocytosis from Saponin-Permeabilized Parotid Acini1

1 reference

12 December 2020

Pseudosubstrate inhibition of cyclic AMP-dependent protein kinase in intact pancreatic islets: effects on cyclic AMP-dependent and glucose-dependent insulin secretion

1 reference

12 December 2020

Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells

1 reference

12 December 2020

The K+-ATP channel-independent pathway of regulation of insulin secretion by glucose: in search of the underlying mechanism

1 reference

12 December 2020

Activation by glucose of adenyl cyclase in pancreatic islets of the rat

1 reference

12 December 2020

Identifiers

DOI

10.1210/ME.2014-1330

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26061564%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26061564%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

26061564

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26061564%20AND%20SRC:MED&resulttype=core&format=json