NRAS mutation causes a human autoimmune lymphoproliferative syndrome. (Q35829141)

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30 December 2019

title

NRAS mutation causes a human autoimmune lymphoproliferative syndrome (English)

1 reference

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autoimmune lymphoproliferative syndrome

30 December 2019

main subject

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author

Joao B. Oliveira

1

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30 December 2019

Julie E. Niemela

3

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Jennifer M Puck

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30 December 2019

author name string

Nicolas Bidère

2

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30 December 2019

Lixin Zheng

4

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30 December 2019

Keiko Sakai

5

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Cynthia P Nix

6

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Robert L Danner

7

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30 December 2019

Jennifer Barb

8

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Peter J Munson

9

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Janet Dale

11

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30 December 2019

Stephen E Straus

12

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30 December 2019

Thomas A Fleisher

13

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30 December 2019

Michael J Lenardo

14

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language of work or name

English

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publication date

16 May 2007

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Proceedings of the National Academy of Sciences of the United States of America

30 December 2019

published in

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30 December 2019

volume

104

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issue

21

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page(s)

8953-8958

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Noonan syndrome and related disorders: dysregulated RAS-mitogen activated protein kinase signal transduction

30 December 2019

cites work

1 reference

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Caspase-8 regulation by direct interaction with TRAF6 in T cell receptor-induced NF-kappaB activation.

11 July 2018

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Cancer targets in the Ras pathway

11 July 2018

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Compartmentalized Ras/MAPK signaling

11 July 2018

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Genetic disorders of programmed cell death in the immune system

11 July 2018

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Germline KRAS mutations cause Noonan syndrome

11 July 2018

1 reference

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Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome

11 July 2018

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Targeting the process of farynesylation for therapy of hematologic malignancies

11 July 2018

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Germline mutations in HRAS proto-oncogene cause Costello syndrome

11 July 2018

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Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy.

11 July 2018

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Effect of common B-RAF and N-RAS mutations on global gene expression in melanoma cell lines

11 July 2018

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The role of BH3-only proteins in the immune system

11 July 2018

1 reference

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Autoimmune lymphoproliferative syndrome.

11 July 2018

1 reference

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T-lymphocyte death during shutdown of an immune response

11 July 2018

1 reference

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Autoimmune lymphoproliferative syndrome with somatic Fas mutations

11 July 2018

1 reference

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Cell death: critical control points

11 July 2018

1 reference

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Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

11 July 2018

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The guanine nucleotide-binding switch in three dimensions

11 July 2018

1 reference

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Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development

11 July 2018

1 reference

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

11 July 2018

1 reference

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Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

11 July 2018

1 reference

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K-ras is an essential gene in the mouse with partial functional overlap with N-ras

11 July 2018

1 reference

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Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease

11 July 2018

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11 July 2018

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Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia

11 July 2018

1 reference

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Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

11 July 2018

1 reference

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Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome.

27 July 2018

1 reference

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Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome

24 September 2018

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RAS oncogenes: the first 30 years.

24 September 2018

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Mice deficient for N-ras: impaired antiviral immune response and T-cell function

24 September 2018

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12 December 2020

N-ras gene point mutations in childhood acute lymphocytic leukemia correlate with a poor prognosis

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12 December 2020

Immunophenotypic profiles in families with autoimmune lymphoproliferative syndrome

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12 December 2020

Regulatory phosphorylation of Bim: sorting out the ERK from the JNK

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0702975104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

0 references

1 reference

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30 December 2019

PubMed publication ID

17517660

1 reference