Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling (Q35840605)

10 August 2017

Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling (English)

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10 August 2017

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Hilary P Glazer

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10 August 2017

Robert M Osipov

2

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10 August 2017

Richard T Clements

3

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10 August 2017

Frank W Sellke

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10 August 2017

Cesario Bianchi

5

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10 August 2017

language of work or name

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3 June 2009

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10 August 2017

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10 August 2017

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10 August 2017

1738-1746

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10 August 2017

11

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describes a project that uses

10 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3308015/fullTextXML

inferred from PubMed Central ID database lookup

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Effect of hypercholesterolemia on myocardial necrosis and apoptosis in the setting of ischemia-reperfusion

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mTOR in growth and protection of hypertrophying myocardium

11 July 2018

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Cardiac regulation by phosphoinositide 3-kinases and PTEN

11 July 2018

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Does reversal of oxidative stress and inflammation provide vascular protection?

11 July 2018

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Modifiable risk factors control and its relationship with 1 year outcomes after coronary artery bypass surgery: insights from the REACH registry

11 July 2018

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11 July 2018

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11 July 2018

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AMP-activated protein kinase: structure and regulation

11 July 2018

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Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

11 July 2018

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The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

11 July 2018

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The malonyl CoA axis as a potential target for treating ischaemic heart disease

11 July 2018

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The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

11 July 2018

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11 July 2018

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Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury

11 July 2018

1 reference

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Recycle or die: the role of autophagy in cardioprotection.

11 July 2018

1 reference

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Akt substrate TBC1D1 regulates GLUT1 expression through the mTOR pathway in 3T3-L1 adipocytes

11 July 2018

1 reference

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Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53.

11 July 2018

1 reference

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Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage

11 July 2018

1 reference

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Endoplasmic reticulum stress as a novel therapeutic target in heart diseases

11 July 2018

1 reference

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Cell survival under nutrient stress is dependent on metabolic conditions regulated by Akt and not by autophagic vacuoles

11 July 2018

1 reference

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Cytosolic LC3 ratio as a sensitive index of macroautophagy in isolated rat hepatocytes and H4-II-E cells

11 July 2018

1 reference

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Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

11 July 2018

1 reference

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Increased Rheb-TOR signaling enhances sensitivity of the whole organism to oxidative stress

11 July 2018

1 reference

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Translational control of gene expression during hypoxia

11 July 2018

1 reference

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Protein turnover in cardiac cell growth and survival

11 July 2018

1 reference

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PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury

11 July 2018

1 reference

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Ras, PI3-kinase and mTOR signaling in cardiac hypertrophy

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308015

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

11 July 2018

1 reference

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Role of clinical pathologies in myocardial injury following ischaemia and reperfusion

11 July 2018

1 reference

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Phosphoinositide 3-kinase accelerates autophagic cell death during glucose deprivation in the rat cardiomyocyte-derived cell line H9c2.

11 July 2018

1 reference

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Modulation of the Protein Kinase Activity of mTOR

11 July 2018

1 reference

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REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species

11 July 2018

1 reference

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Phosphoinositide 3-kinase accelerates necrotic cell death during hypoxia

11 July 2018

1 reference

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Oxidized-LDL enhances coronary vasoconstriction by increasing the activity of protein kinase C isoforms alpha and epsilon

11 July 2018

1 reference

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Dyslipidemia and an unfavorable fatty acid profile predict left ventricular hypertrophy 20 years later

11 July 2018

1 reference

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RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

11 July 2018

1 reference

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Myocardial utilization of carbohydrate and lipids

11 July 2018

1 reference

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Oxidative phosphorylation and aspects of calcium metabolism in myocardia of hypercholesterolaemic swine with moderate coronary atherosclerosis

11 July 2018

1 reference

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Protein kinase C contributes to the maintenance of contractile force in human ventricular cardiomyocytes

11 July 2018

1 reference

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Mediterranean dietary pattern and prediction of all-cause mortality in a US population: results from the NIH-AARP Diet and Health Study

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308015

Rapamycin confers preconditioning-like protection against ischemia-reperfusion injury in isolated mouse heart and cardiomyocytes

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308015

Dyslipidemia is associated with ventricular tachyarrhythmia in patients with acute ST-segment elevation myocardial infarction

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308015

Hypercholesterolemia impairs the myocardial angiogenic response in a swine model of chronic ischemia: role of endostatin and oxidative stress

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308015

Arterial endothelial function in a porcine model of early stage atherosclerotic vascular disease

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308015

Reduced cardiac hypertrophy in toll-like receptor 4-deficient mice following pressure overload

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308015

Insulin stimulates fatty acid transport by regulating expression of FAT/CD36 but not FABPpm

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308015

FKBP12-Rapamycin-associated Protein or Mammalian Target of Rapamycin (FRAP/mTOR) Localization in the Endoplasmic Reticulum and the Golgi Apparatus

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308015

Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308015

FOXO1 regulates the expression of 4E-BP1 and inhibits mTOR signaling in mammalian skeletal muscle

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308015

Implementing American Heart Association Pediatric and Adult Nutrition Guidelines

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308015

Protein kinase C alpha modulates microvascular reactivity in the human coronary and skeletal microcirculation

14 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19395857

12 December 2020

inferred from PubMed ID database lookup

Activation of insulin-like growth factor signaling induces apoptotic cell death under prolonged hypoxia by enhancing endoplasmic reticulum stress response

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19395857

12 December 2020

inferred from PubMed ID database lookup

The development of porcine models of obesity and the metabolic syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19395857

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.4161/CC.8.11.8619

1 reference

10 August 2017

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10 August 2017

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