Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis (Q35842980)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343031%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis (English)

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23 January 2020

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23 January 2020

Seppo Ylä-Herttuala

13

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23 January 2020

Tuomas Tammela

11

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Kari Alitalo

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Raija Sormunen

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Tanja Holopainen

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Anita Lampinen

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Marja Lohela

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Gabriela D'Amico

3

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Lauri Eklund

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23 January 2020

Andrey Anisimov

7

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23 January 2020

Georgia Zarkada

8

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23 January 2020

Hanna Heloterä

10

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23 January 2020

Laura E Benjamin

12

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23 January 2020

Ching Ching Leow

14

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23 January 2020

Gou Young Koh

15

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23 January 2020

language of work or name

English

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publication date

17 February 2012

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Journal of the National Cancer Institute

23 January 2020

published in

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volume

104

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issue

6

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page(s)

461-475

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describes a project that uses

23 January 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3309130/fullTextXML

inferred from PubMed Central ID database lookup

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Host-derived angiopoietin-2 affects early stages of tumor development and vessel maturation but is dispensable for later stages of tumor growth

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo

11 July 2018

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11 July 2018

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An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

11 July 2018

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tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors

11 July 2018

1 reference

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Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.

11 July 2018

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A human monoclonal anti-ANG2 antibody leads to broad antitumor activity in combination with VEGF inhibitors and chemotherapy agents in preclinical models

24 September 2018

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Angiopoietin-1 overexpression modulates vascular endothelium to facilitate tumor cell dissemination and metastasis establishment.

24 September 2018

1 reference

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Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function.

24 September 2018

1 reference

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Tumour-endothelium interactions in co-culture: coordinated changes of gene expression profiles and phenotypic properties of endothelial cells.

24 September 2018

1 reference

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Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

24 September 2018

1 reference

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Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.

24 September 2018

1 reference

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Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis

24 September 2018

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12 December 2020

Angiopoietin-1 and -2 exert antagonistic functions in tumor angiogenesis, yet both induce lymphangiogenesis

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12 December 2020

In vivo actions of angiopoietins on quiescent and remodeling blood and lymphatic vessels in mouse airways and skin

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12 December 2020

Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3'-Kinase/Akt signal transduction pathway

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12 December 2020

Identifiers

DOI

10.1093/JNCI/DJS009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343031%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343031%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343031%20AND%20SRC:MED&resulttype=core&format=json