AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas (Q35843071)

10 August 2017

AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas (English)

1 reference

10 August 2017

Alexander J Lazar

18

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author name string

Caitlin D May

1

1 reference

10 August 2017

Jeannine Garnett

2

1 reference

10 August 2017

XiaoYan Ma

3

1 reference

10 August 2017

Sharon M Landers

4

1 reference

10 August 2017

Davis R Ingram

5

1 reference

10 August 2017

Elizabeth G Demicco

6

1 reference

10 August 2017

Ghadah A Al Sannaa

7

1 reference

10 August 2017

Tona Vu

8

1 reference

10 August 2017

Lixia Han

9

1 reference

10 August 2017

Yi Zhang

10

1 reference

10 August 2017

Christine M Kivlin

11

1 reference

10 August 2017

Svetlana Bolshakov

12

1 reference

10 August 2017

Azad Abul Kalam

13

1 reference

10 August 2017

Juehui Liu

14

1 reference

10 August 2017

Fuguo Zhou

15

1 reference

10 August 2017

Dominique Broccoli

16

1 reference

10 August 2017

Wei-Lien Wang

17

1 reference

10 August 2017

Raphael E Pollock

19

1 reference

10 August 2017

Dina Lev

20

1 reference

10 August 2017

Keila E Torres

21

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10 August 2017

language of work or name

English

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publication date

14 November 2015

1 reference

10 August 2017

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10 August 2017

15

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10 August 2017

901

1 reference

describes a project that uses

10 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4647521/fullTextXML

inferred from PubMed Central ID database lookup

cites work

AXL kinase as a novel target for cancer therapy

1 reference

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Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.

11 July 2018

1 reference

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Axl kinase as a key target for oncology: focus on small molecule inhibitors

11 July 2018

1 reference

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Axl mediates acquired resistance of head and neck cancer cells to the epidermal growth factor receptor inhibitor erlotinib.

11 July 2018

1 reference

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Gas6/Axl mediates tumor cell apoptosis, migration and invasion and predicts the clinical outcome of osteosarcoma patients

11 July 2018

1 reference

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ABL regulation by AXL promotes cisplatin resistance in esophageal cancer

11 July 2018

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NIH Image to ImageJ: 25 years of image analysis

11 July 2018

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Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer

11 July 2018

1 reference

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The receptor tyrosine kinase Axl is an essential regulator of prostate cancer proliferation and tumor growth and represents a new therapeutic target.

11 July 2018

1 reference

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11 July 2018

Cancer statistics, 2012

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Targeting Axl and Mer kinases in cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Axl is a prognostic marker in oral squamous cell carcinoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Pleomorphic liposarcoma: clinical observations and molecular variables

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Activated MET is a molecular prognosticator and potential therapeutic target for malignant peripheral nerve sheath tumors

11 July 2018

1 reference

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Activation of TYRO3/AXL tyrosine kinase receptors in thyroid cancer

11 July 2018

1 reference

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New frontiers in the treatment of liposarcoma, a therapeutically resistant malignant cohort

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

AXL regulates mesothelioma proliferation and invasiveness

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

An experimental model for the study of well-differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Induction, regulation, and biologic function of Axl receptor tyrosine kinase in Kaposi sarcoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Doxorubicin resistance in a novel in vitro model of human pleomorphic liposarcoma associated with alternative lengthening of telomeres

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Novel mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

c-Jun amplification and overexpression are oncogenic in liposarcoma but not always sufficient to inhibit the adipocytic differentiation programme

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Angiogenesis-promoting gene patterns in alveolar soft part sarcoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Retroperitoneal liposarcomas: follow-up analysis of dedifferentiation after clinicopathologic reexamination of 86 liposarcomas and malignant fibrous histiocytomas

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Expression of axl in lung adenocarcinoma and correlation with tumor progression

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Gene expression profiles relate to SS18/SSX fusion type in synovial sarcoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Biological properties and gene expression associated with metastatic potential of human osteosarcoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Structure of the supernumerary ring and giant rod chromosomes in adipose tissue tumors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Requirement of Phosphatidylinositol 3-Kinase-Dependent Pathway and Src for Gas6-Axl Mitogenic and Survival Activities in NIH 3T3 Fibroblasts

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Liposarcoma: outcome and prognostic factors following conservation surgery and radiation therapy

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Differential activation of the Ras/extracellular-signal-regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Activation of the Axl receptor tyrosine kinase induces mitogenesis and transformation in 32D cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

A novel putative tyrosine kinase receptor with oncogenic potential

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Differential expression of Axl and Gas6 in renal cell carcinoma reflecting tumor advancement and survival.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Receptor tyrosine kinase AXL is induced by chemotherapy drugs and overexpression of AXL confers drug resistance in acute myeloid leukemia

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Axl and growth arrest-specific gene 6 are frequently overexpressed in human gliomas and predict poor prognosis in patients with glioblastoma multiforme

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Estrogen dependent expression of the receptor tyrosine kinase axl in normal and malignant human breast

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647521

Pleomorphic liposarcoma: clinicopathologic analysis of 57 cases

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26573603

12 December 2020

inferred from PubMed ID database lookup

Receptor tyrosine kinases expressed in metastatic colon cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26573603

12 December 2020

inferred from PubMed ID database lookup

Axl expression is associated with adverse prognosis and with expression of Bcl-2 and CD34 in de novo acute myeloid leukemia (AML): results from a multicenter trial of the Swiss Group for Clinical Cancer Research (SAKK)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26573603

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1186/S12885-015-1916-3

1 reference

Dimensions Publication ID

10 August 2017

0 references

1 reference

10 August 2017

PubMed publication ID

26573603

1 reference