Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation. (Q35882299)

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scientific article published on 12 March 2012

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English	Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation.	scientific article published on 12 March 2012

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25 January 2020

Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation (English)

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25 January 2020

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25 January 2020

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Hongwei Qin

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25 January 2020

Wen-I Yeh

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Patrizia De Sarno

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Andrew T Holdbrooks

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Michelle T Muldowney

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25 January 2020

Stephanie L Reynolds

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25 January 2020

Lora L Yanagisawa

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25 January 2020

Thomas H Fox

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25 January 2020

Keun Park

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25 January 2020

Laurie E Harrington

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25 January 2020

Chander Raman

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25 January 2020

Etty N Benveniste

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25 January 2020

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12 March 2012

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25 January 2020

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6

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Proceedings of the National Academy of Sciences of the United States of America

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25 January 2020

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25 January 2020

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25 January 2020

5004-5009

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25 January 2020

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

1 reference

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11 July 2018

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

1 reference

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The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.

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IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

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STAT3 in CD4+ T helper cell differentiation and inflammatory diseases

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SOCS1 and SOCS3 in the control of CNS immunity

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Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice

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TGF-beta promotes Th17 cell development through inhibition of SOCS3.

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Autoimmune T cell responses in the central nervous system

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Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.

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Cytokine signaling modules in inflammatory responses

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Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells.

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SOCS proteins, cytokine signalling and immune regulation

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STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

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New vistas on macrophage differentiation and activation

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Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells

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1 reference

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12 December 2020

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inferred from PubMed ID database lookup

CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22411837

12 December 2020

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inferred from PubMed ID database lookup

Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing--remitting experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22411837

12 December 2020

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inferred from PubMed ID database lookup

The effect of disease activity on leptin, leptin receptor and suppressor of cytokine signalling-3 expression in relapsing-remitting multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22411837

12 December 2020

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10.1073/PNAS.1117218109

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25 January 2020

2012PNAS..109.5004Q

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25 January 2020

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25 January 2020

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