Heterogeneity of CNS myeloid cells and their roles in neurodegeneration (Q37939514)

25 August 2017

1 reference

title

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration (English)

1 reference

25 August 2017

Josef Priller

2

0 references

Richard M Ransohoff

series ordinal

4

object named as

Richard M Ransohoff

1 reference

25 August 2017

1

Marco Prinz

1 reference

25 August 2017

Sangram S Sisodia

3

1 reference

PubMed ID

21952260

25 August 2017

language of work or name

English

0 references

publication date

27 September 2011

1 reference

25 August 2017

1 reference

25 August 2017

14

1 reference

25 August 2017

10

1 reference

25 August 2017

1227-1235

1 reference

https://scigraph.springernature.com/pub.10.1038/nn.2923

25 August 2017

0 references

cites work

The myeloid cells of the central nervous system parenchyma

1 reference

Microglia in the CNS: immigrants from another world

21 January 2018

1 reference

Development of monocytes, macrophages, and dendritic cells

21 January 2018

1 reference

Blood monocytes consist of two principal subsets with distinct migratory properties

21 January 2018

1 reference

Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2

21 January 2018

1 reference

Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.

21 January 2018

1 reference

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

21 January 2018

1 reference

ATP mediates rapid microglial response to local brain injury in vivo

21 January 2018

1 reference

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

21 January 2018

1 reference

Microglial interactions with synapses are modulated by visual experience

21 January 2018

1 reference

Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse.

21 January 2018

1 reference

Microglia promote the death of developing Purkinje cells.

21 January 2018

1 reference

Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

21 January 2018

1 reference

Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment.

21 January 2018

1 reference

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

21 January 2018

1 reference

The distribution of microglia and cell death in the fetal rat forebrain

21 January 2018

1 reference

Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain

21 January 2018

1 reference

Origins and functions of phagocytes in the embryo

21 January 2018

1 reference

The origin and differentiation of microglial cells during development

21 January 2018

1 reference

Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

Fate mapping analysis reveals that adult microglia derive from primitive macrophages

21 January 2018

1 reference

Immune cell entry into the central nervous system: involvement of adhesion molecules and chemokines.

21 January 2018

1 reference

Pericytes are required for blood-brain barrier integrity during embryogenesis

21 January 2018

1 reference

Pericytes regulate the blood-brain barrier

21 January 2018

1 reference

Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging

21 January 2018

1 reference

Bone marrow-derived elements in the central nervous system: an immunohistochemical and ultrastructural survey of rat chimeras

21 January 2018

1 reference

Origin and distribution of bone marrow-derived cells in the central nervous system in a mouse model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice.

21 January 2018

1 reference

Early and rapid engraftment of bone marrow-derived microglia in scrapie.

21 January 2018

1 reference

Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice.

21 January 2018

1 reference

Hematopoietic cells maintain hematopoietic fates upon entering the brain.

21 January 2018

1 reference

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.

21 January 2018

1 reference

21 January 2018

1 reference

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

Pathways linking Abeta and tau pathologies.

21 January 2018

1 reference

Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals

21 January 2018

1 reference

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

21 January 2018

1 reference

Coxibs and Alzheimer's disease: should they stay or should they go?

21 January 2018

1 reference

Neuroinflammatory processes in Alzheimer's disease

21 January 2018

1 reference

Inflammation in transgenic mouse models of neurodegenerative disorders

21 January 2018

1 reference

Invasion of hematopoietic cells into the brain of amyloid precursor protein transgenic mice.

21 January 2018

1 reference

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease.

21 January 2018

1 reference

Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia

21 January 2018

1 reference

Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.

21 January 2018

1 reference

Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy.

21 January 2018

1 reference

Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease

21 January 2018

1 reference

Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease

21 January 2018

1 reference

Decreased clearance of CNS beta-amyloid in Alzheimer's disease

21 January 2018

1 reference

Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition.

21 January 2018

1 reference

Rapid microglial response around amyloid pathology after systemic anti-Abeta antibody administration in PDAPP mice

21 January 2018

1 reference

Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice

21 January 2018

1 reference

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

21 January 2018

1 reference

Control of microglial neurotoxicity by the fractalkine receptor

21 January 2018

1 reference

Chemokines and chemokine receptors: standing at the crossroads of immunobiology and neurobiology

21 January 2018

1 reference

Microglial physiology: unique stimuli, specialized responses

21 January 2018

1 reference

Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

21 January 2018

1 reference

CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.

21 January 2018

1 reference

CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-β phagocytosis

21 January 2018

1 reference

Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology

21 January 2018

1 reference

Regulation of tau pathology by the microglial fractalkine receptor

21 January 2018

1 reference

The circumventricular organs participate in the immunopathogenesis of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

Microglia in neurodegenerative disease

21 January 2018

1 reference

Systemic infection, interleukin 1beta, and cognitive decline in Alzheimer's disease.

21 January 2018

1 reference

Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation

21 January 2018

1 reference

Onset and progression in inherited ALS determined by motor neurons and microglia

21 January 2018

1 reference

Macrophage colony stimulating factor (M-CSF) exacerbates ALS disease in a mouse model through altered responses of microglia expressing mutant superoxide dismutase.

21 January 2018

1 reference

Hematopoietic stem cell transplantation in patients with sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease

21 January 2018

1 reference

A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease

21 January 2018

1 reference

Targeting kynurenine 3-monooxygenase (KMO): implications for therapy in Huntington's disease

21 January 2018

1 reference

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

21 January 2018

1 reference

Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease

21 January 2018

1 reference

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

21 January 2018

1 reference

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease

21 January 2018

1 reference

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease

21 January 2018

1 reference

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

21 January 2018

1 reference

NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

21 January 2018

1 reference

Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease

21 January 2018

1 reference

Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease

21 January 2018

1 reference

Bone marrow-derived microglia contribute to the neuroinflammatory response and express iNOS in the MPTP mouse model of Parkinson's disease

21 January 2018

1 reference

Bone-marrow-derived cell differentiation into microglia: a study in a progressive mouse model of Parkinson's disease.

21 January 2018

1 reference

Increased host neuronal survival and motor function in BMT Parkinsonian mice: involvement of immunosuppression

21 January 2018

1 reference

Macrophage-mediated GDNF delivery protects against dopaminergic neurodegeneration: a therapeutic strategy for Parkinson's disease

21 January 2018

1 reference

The genetic causes of basal ganglia calcification, dementia, and bone cysts: DAP12 and TREM2.

21 January 2018

1 reference

Turnover of rat brain perivascular cells.

21 January 2018

1 reference

CD163 identifies perivascular macrophages in normal and viral encephalitic brains and potential precursors to perivascular macrophages in blood

21 January 2018

1 reference

Novel characterization of monocyte-derived cell populations in the meninges and choroid plexus and their rates of replenishment in bone marrow chimeric mice

21 January 2018

1 reference

Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior

21 January 2018

1 reference

Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease

21 January 2018

1 reference

Japanese encephalitis and parkinsonism

21 January 2018

1 reference

12 December 2020

FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-alpha in glial cells.

1 reference

12 December 2020

The value of transgenic models for the study of neurodegenerative diseases

1 reference

12 December 2020

Role of microglial-derived tumor necrosis factor in mediating CD14 transcription and nuclear factor kappa B activity in the brain during endotoxemia

1 reference

12 December 2020

Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage

1 reference

12 December 2020

3D-Reconstruction of microglia and amyloid in APP23 transgenic mice: no evidence of intracellular amyloid

1 reference

12 December 2020

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities

1 reference

12 December 2020

Male donor-derived cells in the brains of female sex-mismatched bone marrow transplant recipients: a Y-chromosome specific in situ hybridization study

1 reference

12 December 2020

Identifiers

DOI

10.1038/NN.2923

1 reference

25 August 2017

1 reference

PubMed ID

21952260