Regulation of cell cycle progression by forkhead transcription factor FOXO3 through its binding partner DNA replication factor Cdt1. (Q35889450)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22451935%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

Regulation of cell cycle progression by forkhead transcription factor FOXO3 through its binding partner DNA replication factor Cdt1 (English)

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27 January 2020

4

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author name string

Yiru Zhang

1

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27 January 2020

Yuqian Xing

2

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27 January 2020

Lei Zhang

3

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27 January 2020

Kazuo Yamamoto

5

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27 January 2020

Tak W Mak

6

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27 January 2020

Han You

7

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27 January 2020

language of work or name

English

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publication date

26 March 2012

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Proceedings of the National Academy of Sciences of the United States of America

27 January 2020

published in

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27 January 2020

volume

109

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27 January 2020

issue

15

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27 January 2020

page(s)

5717-5722

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AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias

27 January 2020

cites work

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Proliferating cell nuclear antigen-dependent rapid recruitment of Cdt1 and CRL4Cdt2 at DNA-damaged sites after UV irradiation in HeLa cells.

11 July 2018

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TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia

11 July 2018

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PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex

11 July 2018

1 reference

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Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1

11 July 2018

1 reference

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FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

11 July 2018

1 reference

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DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint

11 July 2018

1 reference

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A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

11 July 2018

1 reference

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DDB1 maintains genome integrity through regulation of Cdt1

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

An evolutionarily conserved function of proliferating cell nuclear antigen for Cdt1 degradation by the Cul4-Ddb1 ubiquitin ligase in response to DNA damage

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

FOXO transcription factors at the interface between longevity and tumor suppression

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

Degradation of Cdt1 during S phase is Skp2-independent and is required for efficient progression of mammalian cells through S phase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

Geminin-Cdt1 balance is critical for genetic stability

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

Loss of Geminin induces rereplication in the presence of functional p53

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

Rapid degradation of Cdt1 upon UV-induced DNA damage is mediated by SCFSkp2 complex

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification

11 July 2018

1 reference

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Replication origins: why do we need so many?

11 July 2018

1 reference

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The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326503

Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D.

11 July 2018

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The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

11 July 2018

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Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

11 July 2018

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Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins.

11 July 2018

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Making sense of eukaryotic DNA replication origins

11 July 2018

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Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

11 July 2018

1 reference

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Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

11 July 2018

1 reference

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Geminin, an inhibitor of DNA replication, is degraded during mitosis

11 July 2018

1 reference

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Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells

11 July 2018

1 reference

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Regulation of Geminin and Cdt1 expression by E2F transcription factors

11 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1203210109

PI3K-AKT-FoxO axis in cancer and aging.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1203210109

High FOXO3a expression is associated with a poorer prognosis in AML with normal cytogenetics.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1203210109

21 January 2018

Identifiers

DOI

10.1073/PNAS.1203210109

1 reference

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27 January 2020

0 references

1 reference

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27 January 2020

PubMed publication ID

22451935

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22451935%20AND%20SRC:MED&resulttype=core&format=json