Cytotoxic necrotizing factor 1 prevents apoptosis via the Akt/IkappaB kinase pathway: role of nuclear factor-kappaB and Bcl-2 (Q35901851)

11 August 2017

Cytotoxic necrotizing factor 1 prevents apoptosis via the Akt/IkappaB kinase pathway: role of nuclear factor-kappaB and Bcl-2 (English)

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11 August 2017

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Alessandro Giamboi Miraglia

1

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11 August 2017

Sara Travaglione

2

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11 August 2017

Stefania Meschini

3

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Loredana Falzano

4

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Paola Matarrese

5

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11 August 2017

Maria Giovanna Quaranta

6

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11 August 2017

Marina Viora

7

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11 August 2017

Carla Fiorentini

8

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11 August 2017

Alessia Fabbri

9

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11 August 2017

16 May 2007

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Molecular Biology of the Cell

11 August 2017

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18

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7

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11 August 2017

2735-2744

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describes a project that uses

11 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1924812/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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The many shapes of mitochondrial death

11 July 2018

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Mitochondria and cancer: is there a morphological connection?

11 July 2018

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Escherichia coli cytotoxic necrotizing factor 1 blocks cell cycle G2/M transition in uroepithelial cells

11 July 2018

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Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics

11 July 2018

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CNF1-induced ubiquitylation and proteasome destruction of activated RhoA is impaired in Smurf1-/- cells

11 July 2018

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Ubiquitin-mediated proteasomal degradation of Rho proteins by the CNF1 toxin

11 July 2018

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11 July 2018

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Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease

11 July 2018

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Nuclear factor-kappaB activation: a question of life or death

11 July 2018

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Regulation of Ca2+-induced permeability transition by Bcl-2 is antagonized by Drpl and hFis1

11 July 2018

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Unknotting the roles of Bcl-2 and Bcl-xL in cell death

11 July 2018

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Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak

11 July 2018

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Cytotoxic necrotizing factor 1 hinders skeletal muscle differentiation in vitro by perturbing the activation/deactivation balance of Rho GTPases.

11 July 2018

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11 July 2018

Signaling to NF-kappaB

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IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

11 July 2018

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Rac1 inhibits apoptosis in human lymphoma cells by stimulating Bad phosphorylation on Ser-75.

11 July 2018

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Activation and proteasomal degradation of rho GTPases by cytotoxic necrotizing factor-1 elicit a controlled inflammatory response

11 July 2018

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Rac GTPase instructs nuclear factor-kappaB activation by conveying the SCF complex and IkBalpha to the ruffling membranes

11 July 2018

1 reference

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Cytotoxic necrotizing factor 1 enhances reactive oxygen species-dependent transcription and secretion of proinflammatory cytokines in human uroepithelial cells

11 July 2018

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Hijacking Rho GTPases by protein toxins and apoptosis: molecular strategies of pathogenic bacteria.

11 July 2018

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Effect of Bcl-2 overexpression on mitochondrial structure and function

11 July 2018

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Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit

11 July 2018

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Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-kappaB

11 July 2018

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Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.

11 July 2018

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Epithelial cells infected with Chlamydophila pneumoniae (Chlamydia pneumoniae) are resistant to apoptosis.

11 July 2018

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Activation of the RacGTPase inhibits apoptosis in human tumor cells

11 July 2018

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Activation of rho GTPases by cytotoxic necrotizing factor 1 induces macropinocytosis and scavenging activity in epithelial cells

11 July 2018

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Hijacking of apoptotic pathwaysby bacterial pathogens

11 July 2018

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Apoptosis induced by Rac GTPase correlates with induction of FasL and ceramides production

11 July 2018

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Regulation of Bcl-xL: a little bit of this and a little bit of STAT.

11 July 2018

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The p21 Rho-activating toxin cytotoxic necrotizing factor 1 is endocytosed by a clathrin-independent mechanism and enters the cytosol by an acidic-dependent membrane translocation step

11 July 2018

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Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

11 July 2018

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

11 July 2018

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Anti-apoptotic function of Rac in hematopoietic cells.

11 July 2018

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Deamidation of Cdc42 and Rac by Escherichia coli cytotoxic necrotizing factor 1: activation of c-Jun N-terminal kinase in HeLa cells.

11 July 2018

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Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

11 July 2018

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Toxin-induced activation of Rho GTP-binding protein increases Bcl-2 expression and influences mitochondrial homeostasis

11 July 2018

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

11 July 2018

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The Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity. Cysteine 866 and histidine 881 are essential for enzyme activity

11 July 2018

1 reference

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Rho GTPases and the actin cytoskeleton

11 July 2018

1 reference

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Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924812

Cytotoxic necrotizing factor 1 from Escherichia coli and dermonecrotic toxin from Bordetella bronchiseptica induce p21(rho)-dependent tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 cells

11 July 2018

1 reference

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The NF-kappa B and I kappa B proteins: new discoveries and insights

11 July 2018

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Rac GTPase interacts specifically with phosphatidylinositol 3-kinase

11 July 2018

1 reference

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Induction of phagocytic behaviour in human epithelial cells by Escherichia coli cytotoxic necrotizing factor type 1.

11 July 2018

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3-Aminobenzamide protects cells from UV-B-induced apoptosis by acting on cytoskeleton and substrate adhesion.

11 July 2018

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Cytoskeletal changes induced in HEp-2 cells by the cytotoxic necrotizing factor of Escherichia coli

11 July 2018

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I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

11 July 2018

1 reference

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67-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain microvascular endothelial cells.

11 July 2018

1 reference

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CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion

24 September 2018

1 reference

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Rac1 inhibits TNF-alpha-induced endothelial cell apoptosis: dual regulation by reactive oxygen species

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924812

Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924812

Frequency of Escherichia coli strains producing the cytotoxic necrotizing factor (CNF1) in nosocomial urinary tract infections

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17507655

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Failure of Bcl-2 to block cytochrome c redistribution during TRAIL-induced apoptosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17507655

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E06-10-0910

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

17507655

1 reference