Identification of SR2211: a potent synthetic RORγ-selective modulator. (Q35903192)

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21 January 2020

title

Identification of SR2211: a potent synthetic RORγ-selective modulator (English)

1 reference

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21 January 2020

6

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21 January 2020

7

Theodore M Kamenecka

1 reference

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21 January 2020

author name string

Naresh Kumar

1

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21 January 2020

Brent Lyda

2

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21 January 2020

Mi Ra Chang

3

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21 January 2020

Janelle L Lauer

4

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21 January 2020

Laura A Solt

5

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21 January 2020

Patrick R Griffin

8

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21 January 2020

publication date

13 February 2012

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21 January 2020

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21 January 2020

volume

7

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21 January 2020

page(s)

672-677

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21 January 2020

issue

4

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Structural Basis of Digoxin That Antagonizes ROR t Receptor Activity and Suppresses Th17 Cell Differentiation and Interleukin (IL)-17 Production

21 January 2020

cites work

1 reference

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Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORgamma t protein

27 July 2018

1 reference

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Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

27 July 2018

1 reference

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Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity

27 July 2018

1 reference

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Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331898

Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands

27 July 2018

1 reference

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Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells

27 July 2018

1 reference

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27 July 2018

1 reference

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T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

27 July 2018

1 reference

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

27 July 2018

1 reference

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Ursolic acid-induced down-regulation of MMP-9 gene is mediated through the nuclear translocation of glucocorticoid receptor in HT1080 human fibrosarcoma cells

27 July 2018

1 reference

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Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331898

The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist.

24 September 2018

1 reference

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Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22292739

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/CB200496Y

1 reference

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21 January 2020

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21 January 2020

1 reference

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