CD80 expression on B cells regulates murine T follicular helper development, germinal center B cell survival, and plasma cell generation (Q35903317)

11 August 2017

CD80 expression on B cells regulates murine T follicular helper development, germinal center B cell survival, and plasma cell generation (English)

1 reference

11 August 2017

Kim L Good-Jacobson

1

1 reference

11 August 2017

Eunice Song

2

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11 August 2017

Shannon Anderson

3

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11 August 2017

Arlene H Sharpe

4

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11 August 2017

Mark J Shlomchik

5

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11 August 2017

language of work or name

English

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publication date

26 March 2012

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11 August 2017

Journal of Immunology

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11 August 2017

188

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11 August 2017

9

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11 August 2017

4217-4225

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describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3331930/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6

27 July 2018

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Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone

27 July 2018

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B cell-specific expression of B7-2 is required for follicular Th cell function in response to vaccinia virus

27 July 2018

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B7-H1 expression on non-B and non-T cells promotes distinct effects on T- and B-cell responses in autoimmune arthritis.

27 July 2018

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Plasticity and heterogeneity in the generation of memory B cells and long-lived plasma cells: the influence of germinal center interactions and dynamics.

27 July 2018

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Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)

27 July 2018

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In vivo regulation of Bcl6 and T follicular helper cell development

27 July 2018

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PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells

27 July 2018

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IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

27 July 2018

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IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

27 July 2018

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Taking advantage: high-affinity B cells in the germinal center have lower death rates, but similar rates of division, compared to low-affinity cells

27 July 2018

1 reference

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Cytokine-secreting follicular T cells shape the antibody repertoire

27 July 2018

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Systematic comparison of gene expression between murine memory and naive B cells demonstrates that memory B cells have unique signaling capabilities

27 July 2018

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PD-1 and its ligands in tolerance and immunity

27 July 2018

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Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses

27 July 2018

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Stromal niches, plasma cell differentiation and survival.

27 July 2018

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A critical role for IL-21 in regulating immunoglobulin production

27 July 2018

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Memory B cells without somatic hypermutation are generated from Bcl6-deficient B cells

27 July 2018

1 reference

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ICOS is essential for effective T-helper-cell responses

27 July 2018

1 reference

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ICOS co-stimulatory receptor is essential for T-cell activation and function

27 July 2018

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Germinal center initiation, variable gene region hypermutation, and mutant B cell selection without detectable immune complexes on follicular dendritic cells

27 July 2018

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Germinal centers without T cells

27 July 2018

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Immunological memory and protective immunity: understanding their relation

27 July 2018

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice

27 July 2018

1 reference

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In situ studies of the antigen-driven somatic hypermutation of immunoglobulin genes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity.

27 July 2018

1 reference

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Multiple layers of B cell memory with different effector functions

24 September 2018

1 reference

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IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

Resting human memory B cells are intrinsically programmed for enhanced survival and responsiveness to diverse stimuli compared to naive B cells.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

New markers for murine memory B cells that define mutated and unmutated subsets

24 September 2018

1 reference

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Imaging of germinal center selection events during affinity maturation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

Two waves of memory B-cell generation in the primary immune response.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

Differential requirements for expression of CD80/86 and CD40 on B cells for T-dependent antibody responses in vivo

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

The interaction properties of costimulatory molecules revisited.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

Immunological memory: contribution of memory B cells expressing costimulatory molecules in the resting state.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

ICOS is critical for CD40-mediated antibody class switching

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

Relaxed negative selection in germinal centers and impaired affinity maturation in bcl-xL transgenic mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affinity maturation develops in two stages of clonal selection.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

CD28 is required for germinal center formation.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331930

B and T Lymphocyte Attenuator Suppresses IL-21 Production from Follicular Th Cells and Subsequent Humoral Immune Responses

22 October 2018

1 reference

12 December 2020

CDK inhibitor p18(INK4c) is required for the generation of functional plasma cells

1 reference

12 December 2020

Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus

1 reference

12 December 2020

Differential up-regulation of the B7-1 and B7-2 costimulatory molecules after Ig receptor engagement by antigen

1 reference

12 December 2020

Role of costimulators in T cell differentiation: studies using antigen-presenting cells lacking expression of CD80 or CD86

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1102885

1 reference

11 August 2017

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11 August 2017

1 reference