IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism (Q33656121)

28 July 2017

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism (English)

1 reference

28 July 2017

cell-intrinsic mechanism

1 reference

1 reference

Yang Zhang

3

0 references

Jonathan Coquet

Jonathan M Coquet

2

0 references

David M Tarlinton

David M Tarlinton

12

0 references

Kai-Michael Toellner

Kai-Michael Toellner

9

0 references

Stephen L. Nutt

Stephen L Nutt

11

0 references

Dale I Godfrey

Dale I Godfrey

8

0 references

Mark J. Smyth

Mark J Smyth

10

0 references

Lynn M. Corcoran

7

Lynn M Corcoran

1 reference

28 July 2017

6

Axel Kallies

1 reference

28 July 2017

Dimitra Zotos

1

1 reference

28 July 2017

Amanda Light

4

1 reference

28 July 2017

Kathy D'Costa

5

1 reference

28 July 2017

language of work or name

English

0 references

publication date

8 February 2010

1 reference

Journal of Experimental Medicine

28 July 2017

1 reference

28 July 2017

207

1 reference

28 July 2017

365-378

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28 July 2017

2

1 reference

A vital role for interleukin-21 in the control of a chronic viral infection

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Cytokine-secreting follicular T cells shape the antibody repertoire

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Follicular helper T cells are required for systemic autoimmunity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

The role of IL-21 in regulating B-cell function in health and disease.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

A fundamental role for interleukin-21 in the generation of T follicular helper cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Germinal-center organization and cellular dynamics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Antigen receptor diversification and chromosome translocations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

B-cell memory: are subsets necessary?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Follicular B helper T cells in antibody responses and autoimmunity.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Reassessing the function of immune-complex retention by follicular dendritic cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Progressive differentiation and selection of the fittest in the immune response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

A critical role for IL-21 in regulating immunoglobulin production

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Memory B cells without somatic hypermutation are generated from Bcl6-deficient B cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Signatures of the immune response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

JunD/AP-1 and STAT3 are the major enhancer molecules for high Bcl6 expression in germinal center B cells.

28 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091777

The who, how and where of antigen presentation to B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091777

IL-21-induced Bepsilon cell apoptosis mediated by natural killer T cells suppresses IgE responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091777

Two waves of memory B-cell generation in the primary immune response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091777

Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091777

IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091777

High affinity germinal center B cells are actively selected into the plasma cell compartment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091777

A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091777

IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091777

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affinity maturation develops in two stages of clonal selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091777

Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091777

A novel mutation in the Nfkb2 gene generates an NF-kappa B2 "super repressor".

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091777

Kinetics of establishing the memory B cell population as revealed by CD38 expression.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822601

Stages of germinal center transit are defined by B cell transcription factor coexpression and relative abundance

30 October 2018

1 reference

12 December 2020

Cutting Edge: IL-21 Is Not Essential for Th17 Differentiation or Experimental Autoimmune Encephalomyelitis

1 reference

12 December 2020

Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses

1 reference

12 December 2020

Structure of primary anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in normal and idiotypically suppressed C57BL/6 mice

1 reference

12 December 2020

Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20091777

1 reference

28 July 2017

1 reference

28 July 2017

1 reference