Spermine synthase overexpression in vivo does not increase susceptibility to DMBA/TPA skin carcinogenesis or Min-Apc intestinal tumorigenesis (Q35925417)

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scientific article published in April 2012

Language	Label	Description	Also known as
English	Spermine synthase overexpression in vivo does not increase susceptibility to DMBA/TPA skin carcinogenesis or Min-Apc intestinal tumorigenesis	scientific article published in April 2012

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Spermine synthase overexpression in vivo does not increase susceptibility to DMBA/TPA skin carcinogenesis or Min-Apc intestinal tumorigenesis (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Patricia A Welsh

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Suzanne Sass-Kuhn

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Chethana Prakashagowda

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Diane McCloskey

4

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

David Feith

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

publication date

1 April 2012

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Cancer Biology and Therapy

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

13

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

358-368

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Characterization of transgenic mice with overexpression of spermidine synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Regulation of cyclin-dependent kinase 4 translation through CUG-binding protein 1 and microRNA-222 by polyamines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

A prolonged and exaggerated wound response with elevated ODC activity mimics early tumor development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Defining the role of polyamines in colon carcinogenesis using mouse models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Regulation of cellular polyamine levels and cellular proliferation by antizyme and antizyme inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

S-Adenosylmethionine decarboxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

A randomized, double-blind, placebo-controlled phase 3 skin cancer prevention study of {alpha}-difluoromethylornithine in subjects with previous history of skin cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Modulation of cellular function by polyamines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Mammalian polyamine metabolism and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Polyamine catabolism and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Combination chemoprevention for colon cancer targeting polyamine synthesis and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Spermine synthase deficiency leads to deafness and a profound sensitivity to alpha-difluoromethylornithine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Polyamines and mRNA stability in regulation of intestinal mucosal growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Polyamine metabolism and tumorigenesis in the Apc(Min/+) mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Polyamines and neoplastic growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Polyamines and nonmelanoma skin cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Regulation of ornithine decarboxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Genetic manipulation of polyamine catabolism in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Aminopropyltransferases: function, structure and genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Potent modulation of intestinal tumorigenesis in Apcmin/+ mice by the polyamine catabolic enzyme spermidine/spermine N1-acetyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Polyamines and cancer: old molecules, new understanding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Genetic approaches to the cellular functions of polyamines in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Thirty Years of Polyamine-Related Approaches to Cancer Therapy. Retrospect and Prospect. Part 1. Selective Enzyme Inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

A perspective of polyamine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Polyamine-dependent gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

APC-dependent regulation of ornithine decarboxylase in human colon tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

The ornithine decarboxylase gene is essential for cell survival during early murine development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Regulation of cellular polyamines by antizyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Regulation of ornithine decarboxylase gene expression in mouse epidermis and epidermal tumors during two-stage tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

2 October 2017

Tumor suppressor activity of ODC antizyme in MEK-driven skin tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

11 July 2018

Overproduction of cardiac S-adenosylmethionine decarboxylase in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

11 July 2018

Spermine synthesis is required for normal viability, growth, and fertility in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

11 July 2018

Characterization of transgenic mice with widespread overexpression of spermine synthase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

11 July 2018

Effect of spermine synthase on the sensitivity of cells to anti-tumour agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

11 July 2018

Effect of spermine synthase deficiency on polyamine biosynthesis and content in mice and embryonic fibroblasts, and the sensitivity of fibroblasts to 1,3-bis-(2-chloroethyl)-N-nitrosourea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

11 July 2018

Studies of neoplasia in the Min mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

11 July 2018

Constitutively elevated levels of ornithine and polyamines in mouse epidermal papillomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

11 July 2018

Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide.

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

Essential role of S-adenosylmethionine decarboxylase in mouse embryonic development

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

Combination chemoprevention of intestinal carcinogenesis in a murine model of familial adenomatous polyposis

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

Mouse skin chemical carcinogenesis is inhibited by antizyme in promotion-sensitive and promotion-resistant genetic backgrounds.

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

Spermine synthase activity affects the content of decarboxylated S-adenosylmethionine

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

Haploinsufficiency for odc modifies mouse skin tumor susceptibility

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

Activated polyamine catabolism depletes acetyl-CoA pools and suppresses prostate tumor growth in TRAMP mice

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

Changes in epidermal polyamine biosynthesis and specific activity of DNA following a single application of 12-O-tetradecanoyl-phorbol-13-acetate to hairless mouse skin.

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

Dose de-escalation chemoprevention trial of alpha-difluoromethylornithine in patients with colon polyps

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

Differential gene expression in epidermis of mice sensitive and resistant to phorbol ester skin tumor promotion

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

Elevated Epidermal Ornithine Decarboxylase Activity Suppresses Contact Hypersensitivity

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

A missense mutation, p.V132G, in the X-linked spermine synthase gene (SMS) causes Snyder-Robinson syndrome.

1 reference

https://api.crossref.org/works/10.4161%2FCBT.19241

21 January 2018

Targeted antizyme expression in the skin of transgenic mice reduces tumor promoter induction of ornithine decarboxylase and decreases sensitivity to chemical carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

24 September 2018

Ornithine decarboxylase and polyamines in familial adenomatous polyposis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

24 September 2018

Degree of enhancement of polyamine biosynthetic decarboxylase activities in human tumors: a useful new index of degree of malignancy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341213

24 September 2018

Chemopreventive efficacy of combined piroxicam and difluoromethylornithine treatment of Apc mutant Min mouse adenomas, and selective toxicity against Apc mutant embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/22258329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carcinogenesis studies in mice with genetically engineered alterations in polyamine metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/22258329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/22258329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The induction of ornithine decarboxylase as an early, possibly obligatory, event in mouse skin carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22258329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of the mechanism by which increased spermidine/spermine N1-acetyltransferase activity increases susceptibility to skin carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22258329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/CBT.19241

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

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