NSC-640358 acts as RXRα ligand to promote TNFα-mediated apoptosis of cancer cell (Q35956818)

11 August 2017

NSC-640358 acts as RXRα ligand to promote TNFα-mediated apoptosis of cancer cell (English)

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11 August 2017

Fan Chen

1

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11 August 2017

Jiebo Chen

2

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11 August 2017

Jiacheng Lin

3

1 reference

11 August 2017

Anton V Cheltsov

4

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11 August 2017

Lin Xu

5

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11 August 2017

Ya Chen

6

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11 August 2017

Zhiping Zeng

7

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11 August 2017

Liqun Chen

8

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11 August 2017

Mingfeng Huang

9

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11 August 2017

Mengjie Hu

10

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11 August 2017

Xiaohong Ye

11

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11 August 2017

Yuqi Zhou

12

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11 August 2017

Guanghui Wang

13

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11 August 2017

Ying Su

14

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11 August 2017

Long Zhang

15

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11 August 2017

Fangfang Zhou

16

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11 August 2017

Xiao-Kun Zhang

17

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11 August 2017

Hu Zhou

18

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11 August 2017

9 July 2015

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11 August 2017

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11 August 2017

6

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11 August 2017

654-666

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11 August 2017

9

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Creative Commons Attribution 4.0 International

11 August 2017

start time

9 July 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1007/s13238-015-0178-9

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cites work

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2 October 2017

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Probing of exosites leads to novel inhibitor scaffolds of HCV NS3/4A proteinase

2 October 2017

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An emerging role for retinoid X receptor α in malignant hematopoiesis

2 October 2017

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Novel MT1-MMP small-molecule inhibitors based on insights into hemopexin domain function in tumor growth

2 October 2017

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Molecular Determinants of Magnolol Targeting Both RXRα and PPARγ

2 October 2017

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The retinoid X receptors and their ligands

2 October 2017

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Modulation of RXR function through ligand design

2 October 2017

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Structure basis of bigelovin as a selective RXR agonist with a distinct binding mode

2 October 2017

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Targeting NR4A1 (TR3) in cancer cells and tumors

2 October 2017

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The “Phantom Effect” of the Rexinoid LG100754: Structural and Functional Insights

2 October 2017

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Danthron Functions as a Retinoic X Receptor Antagonist by Stabilizing Tetramers of the Receptor

2 October 2017

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Retinoids, retinoic acid receptors, and cancer

2 October 2017

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Virtual ligand screening of the National Cancer Institute (NCI) compound library leads to the allosteric inhibitory scaffolds of the West Nile Virus NS3 proteinase

2 October 2017

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Retinoid X receptors: common heterodimerization partners with distinct functions

2 October 2017

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NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling

2 October 2017

1 reference

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TNF and cancer: the two sides of the coin

2 October 2017

1 reference

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Design of selective nuclear receptor modulators: RAR and RXR as a case study

2 October 2017

1 reference

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RAR and RXR modulation in cancer and metabolic disease

2 October 2017

1 reference

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p53 and Nur77/TR3 - transcription factors that directly target mitochondria for cell death induction

2 October 2017

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Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: roles for JNK and SER260.

2 October 2017

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Retinoid x receptor heterodimers in the metabolic syndrome

2 October 2017

1 reference

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Retinoid X receptors: X-ploring their (patho)physiological functions

2 October 2017

1 reference

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Decreased expression of retinoid X receptor isoforms in human thyroid carcinomas

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537469

Principles for modulation of the nuclear receptor superfamily

2 October 2017

1 reference

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Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537469

Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: A novel mechanism for reduced hepatic gene expression in inflammation

2 October 2017

1 reference

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Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

2 October 2017

1 reference

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Mitogenic Effect of Orphan Receptor TR3 and Its Regulation by MEKK1 in Lung Cancer Cells

2 October 2017

1 reference

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Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors

2 October 2017

1 reference

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Prostatic intraepithelial neoplasia in mice with conditional disruption of the retinoid X receptor alpha allele in the prostate epithelium

2 October 2017

1 reference

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The activation function-1 domain of Nur77/NR4A1 mediates trans-activation, cell specificity, and coactivator recruitment

2 October 2017

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Molecular recognition of agonist ligands by RXRs

2 October 2017

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Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.

2 October 2017

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Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537469

Expression of nuclear retinoid receptors in normal, premalignant and malignant gastric tissues determined by in situ hybridization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537469

Cleavage of RXRalpha by a lysosomal enzyme, cathepsin L-type protease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537469

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537469

Endocrine regulation of mitochondrial activity: involvement of truncated RXRalpha and c-Erb Aalpha1 proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537469

Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537469

Phosphorylation of retinoid X receptor alpha at serine 260 impairs its metabolism and function in human hepatocellular carcinoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537469

Apoptosis induction in cancer cells by a novel analogue of 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid lacking retinoid receptor transcriptional activation activity.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537469

Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537469

Intracellular proteolytic cleavage of 9-cis-retinoic acid receptor alpha by cathepsin L-type protease is a potential mechanism for modulating thyroid hormone action

24 September 2018

1 reference

12 December 2020

Modulation of retinoid signalling through NGF-induced nuclear export of NGFI-B

1 reference

12 December 2020

Differential expression of nuclear retinoid receptors in normal and malignant prostates

1 reference

12 December 2020

Tumour necrosis factor and cancer

1 reference

12 December 2020

Tumour necrosis factor and cancer

1 reference

12 December 2020

10.1007/S13238-015-0178-9

Identifiers

DOI

1 reference

11 August 2017

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11 August 2017

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