Cytoplasmic p27 promotes epithelial-mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation (Q35958293)

11 August 2017

Cytoplasmic p27 promotes epithelial-mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation (English)

1 reference

11 August 2017

1 reference

1

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2 June 2020

Wen Zhou

5

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2 June 2020

Michael A Durante

8

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2 June 2020

author name string

A H Besser

2

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2 June 2020

S A Wander

3

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2 June 2020

J Sun

4

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2 June 2020

B Wang

6

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2 June 2020

T Ince

7

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2 June 2020

W Guo

9

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2 June 2020

G Mills

10

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2 June 2020

D Theodorescu

11

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2 June 2020

J Slingerland

12

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2 June 2020

language of work or name

English

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publication date

16 February 2015

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11 August 2017

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2 June 2020

volume

34

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2 June 2020

issue

43

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2 June 2020

page(s)

5447-5459

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

2 June 2020

copyright license

start time

16 February 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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The basics of epithelial-mesenchymal transition

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RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility

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2 October 2017

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2 October 2017

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2 October 2017

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p27Kip1 modulates cell migration through the regulation of RhoA activation.

2 October 2017

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Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

2 October 2017

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PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

2 October 2017

1 reference

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PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

2 October 2017

1 reference

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Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

2 October 2017

1 reference

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Regulation of the cdk inhibitor p27 and its deregulation in cancer

2 October 2017

1 reference

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The murine gene p27Kip1 is haplo-insufficient for tumour suppression

2 October 2017

1 reference

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Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

2 October 2017

1 reference

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A cell cycle-regulated inhibitor of cyclin-dependent kinases

2 October 2017

1 reference

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A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

The cell cycle inhibitor p27Kip¹ controls self-renewal and pluripotency of human embryonic stem cells by regulating the cell cycle, Brachyury and Twist

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

Cytoplasmic p27 is oncogenic and cooperates with Ras both in vivo and in vitro

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

The combination of low cytoplasmic and high nuclear expression of p27 predicts a better prognosis in high-grade astrocytoma.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

Biological correlates of p27 compartmental expression in prostate cancer.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

Phosphorylation of p27Kip1 at Threonine 198 by p90 Ribosomal Protein S6 Kinases Promotes Its Binding to 14-3-3 and Cytoplasmic Localization

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

Proteasome-dependent degradation of p27/kip1 in gliomas

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4537852

Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2014.473

31 March 2020

Identifiers

DOI

10.1038/ONC.2014.473

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25684140%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25684140%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

PubMed publication ID

25684140

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25684140%20AND%20SRC:MED&resulttype=core&format=json