Oncogenic roles of EMT-inducing transcription factors (Q38215948)

31 August 2017

Oncogenic roles of EMT-inducing transcription factors (English)

1 reference

31 August 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875735%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Julie Caramel

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875735%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Thomas Brabletz

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875735%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

publication date

1 June 2014

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31 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875735%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875735%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875735%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

488-494

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875735%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/ncb2976

5 June 2020

exact match

0 references

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Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

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Erk5 controls Slug expression and keratinocyte activation during wound healing

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Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

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Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

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Adaptation versus selection: the origins of metastatic behavior

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Regulatory networks defining EMT during cancer initiation and progression

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Epithelial--mesenchymal and mesenchymal--epithelial transitions in carcinoma progression.

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EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice.

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Tumor metastasis: molecular insights and evolving paradigms

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The basics of epithelial-mesenchymal transition

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The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity

21 January 2018

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The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

21 January 2018

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Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis

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A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer

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Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition

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A Twist-Snail axis critical for TrkB-induced epithelial-mesenchymal transition-like transformation, anoikis resistance, and metastasis

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Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis

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Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

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Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1.

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Snail blocks the cell cycle and confers resistance to cell death

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Phenotypic plasticity and epithelial-mesenchymal transitions in cancer and normal stem cells?

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Epithelial-mesenchymal transition: a cancer researcher's conceptual friend and foe.

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Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells

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Systemic spread is an early step in breast cancer

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EMT and dissemination precede pancreatic tumor formation

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Nuclear Snail1 and nuclear ZEB1 protein expression in invasive and intraductal human breast carcinomas

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Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer

21 January 2018

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Epithelial to mesenchymal transition in early stage endometrioid endometrial carcinoma

21 January 2018

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Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype

21 January 2018

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Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma

21 January 2018

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The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers.

21 January 2018

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EMT tumorigenesis in the mouse mammary gland

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Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells

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Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer

21 January 2018

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Deconstructing the molecular portraits of breast cancer

21 January 2018

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Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics

21 January 2018

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The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

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Molecular mechanisms of epithelial-mesenchymal transition

21 January 2018

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Inflammation and EMT: an alliance towards organ fibrosis and cancer progression

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Tissue deformation modulates twist expression to determine anterior midgut differentiation in Drosophila embryos.

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Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer.

21 January 2018

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ERK2 but not ERK1 induces epithelial-to-mesenchymal transformation via DEF motif-dependent signaling events

21 January 2018

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TWISTing an embryonic transcription factor into an oncoprotein

21 January 2018

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Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence

21 January 2018

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Twist is a potential oncogene that inhibits apoptosis

21 January 2018

1 reference

Oncogenic cooperation between H-Twist and N-Myc overrides failsafe programs in cancer cells.

21 January 2018

1 reference

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

21 January 2018

1 reference

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

21 January 2018

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

21 January 2018

1 reference

Tumour biology: senescence in premalignant tumours

21 January 2018

1 reference

A "twist box" code of p53 inactivation: twist box: p53 interaction promotes p53 degradation

21 January 2018

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Zeb1 links epithelial-mesenchymal transition and cellular senescence

21 January 2018

1 reference

Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors

21 January 2018

1 reference

Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response

21 January 2018

1 reference

Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma

21 January 2018

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Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function

21 January 2018

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Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress

21 January 2018

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TWIST1 a new determinant of epithelial to mesenchymal transition in EGFR mutated lung adenocarcinoma

21 January 2018

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Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis

21 January 2018

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SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells

21 January 2018

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Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines

21 January 2018

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Stem cell concepts renew cancer research

21 January 2018

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

21 January 2018

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Generation of breast cancer stem cells through epithelial-mesenchymal transition

21 January 2018

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Twist modulates breast cancer stem cells by transcriptional regulation of CD24 expression

21 January 2018

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Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

21 January 2018

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Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition

21 January 2018

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The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling

21 January 2018

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Eaten alive: a history of macroautophagy

21 January 2018

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

21 January 2018

1 reference

Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells

21 January 2018

1 reference

Slug and Sox9 cooperatively determine the mammary stem cell state

21 January 2018

1 reference

Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity

21 January 2018

1 reference

p53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome

21 January 2018

1 reference

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

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Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

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The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells.

21 January 2018

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p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

21 January 2018

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Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal

21 January 2018

1 reference

A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity

21 January 2018

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Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

21 January 2018

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Linking the p53 tumour suppressor pathway to somatic cell reprogramming

21 January 2018

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Amplification of PRKCI, located in 3q26, is associated with lymph node metastasis in esophageal squamous cell carcinoma

21 January 2018

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The tumorigenicity of diploid and aneuploid human pluripotent stem cells

21 January 2018

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Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures.

21 January 2018

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RB1 and p53 at the crossroad of EMT and triple-negative breast cancer.

21 January 2018

1 reference

Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.

21 January 2018

1 reference

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

21 January 2018

1 reference

p63 Is essential for the proliferative potential of stem cells in stratified epithelia

21 January 2018

1 reference

p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs.

21 January 2018

1 reference

A microRNA component of the p53 tumour suppressor network

21 January 2018

1 reference

The miR-34 family in cancer and apoptosis

21 January 2018

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p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2.

21 January 2018

1 reference

The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?

21 January 2018

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A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition

21 January 2018

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A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

21 January 2018

1 reference

miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

21 January 2018

1 reference

p53-induced miR-15a/16-1 and AP4 form a double-negative feedback loop to regulate epithelial-mesenchymal transition and metastasis in colorectal cancer

21 January 2018

1 reference

TWIST family of basic helix-loop-helix transcription factors mediate human mesenchymal stem cell growth and commitment.

21 January 2018

1 reference

SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.

21 January 2018

1 reference

The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization.

21 January 2018

1 reference

Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate

21 January 2018

1 reference

A switch in the expression of embryonic EMT-inducers drives the development of malignant melanoma.

21 January 2018

1 reference

Cancer stem cells versus phenotype-switching in melanoma

21 January 2018

1 reference

Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized

21 January 2018

1 reference

Slug expression during melanoma progression

21 January 2018

1 reference

SLUG (SNAI2) deletions in patients with Waardenburg disease

21 January 2018

1 reference

Deletion of the SLUG (SNAI2) gene results in human piebaldism

21 January 2018

1 reference

Melanocytes and the microphthalmia transcription factor network

21 January 2018

1 reference

Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome

21 January 2018

1 reference

ZFHX1B mutations in patients with Mowat-Wilson syndrome

21 January 2018

1 reference

Mutations in SIP1, encoding Smad interacting protein-1, cause a form of Hirschsprung disease

21 January 2018

1 reference

In vivo identification of tumor- suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma

21 January 2018

1 reference

Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition.

21 January 2018

1 reference

Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells.

21 January 2018

1 reference

Zeb1 represses Mitf and regulates pigment synthesis, cell proliferation, and epithelial morphology

21 January 2018

1 reference

The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

21 January 2018

1 reference

Cancer. The metastasis cascade

21 January 2018

1 reference

Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer

21 January 2018

1 reference

To differentiate or not--routes towards metastasis

21 January 2018

1 reference

12 December 2020

Loss of heterozygosity analysis shows monoclonal evolution with frequent genetic progression and divergence in esophageal carcinosarcoma

1 reference

12 December 2020

EMT and MET in metastasis: where are the cancer stem cells?

1 reference

12 December 2020

20 years studying p53 functions in genetically engineered mice

1 reference

12 December 2020

Evidence that fibroblasts derive from epithelium during tissue fibrosis

1 reference

12 December 2020

The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer

1 reference

12 December 2020

Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition

1 reference

12 December 2020

The Ink4/Arf locus is a barrier for iPS cell reprogramming

1 reference

12 December 2020

Stem cell regulation, tissue ontogeny, and oncogenic events

1 reference

12 December 2020

Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis

1 reference

12 December 2020

Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential

1 reference

12 December 2020

Regulation of apoptosis and differentiation by p53 in human embryonic stem cells

1 reference

12 December 2020

Childhood solid tumours: a developmental disorder

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCB2976

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875735%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 June 2020

1003892249

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Fatcat ID

release_qx2xeko3xzclfh2lw2zsa44fqm

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Fatcat

https://api.fatcat.wiki/v0/release/qx2xeko3xzclfh2lw2zsa44fqm

24 November 2022

mapped directly with Wikidata item

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