Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting (Q35964550)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21309747%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

review article

1 reference

title

Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21309747%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

main subject

endoplasmic reticulum

0 references

author

Amy S Lee

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21309747%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Min Ni

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21309747%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Yi Zhang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21309747%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

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publication date

1 March 2011

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22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21309747%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

434

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22 January 2020

page(s)

181-188

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22 January 2020

issue

2

1 reference

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Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores

22 January 2020

cites work

1 reference

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2 October 2017

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2 October 2017

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2 October 2017

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Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance

2 October 2017

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Molecular chaperone BiP interacts with Borna disease virus glycoprotein at the cell surface

2 October 2017

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The endoplasmic reticulum chaperone BiP/GRP78 is important in the structure and function of the human cytomegalovirus assembly compartment

2 October 2017

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Regulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiP

2 October 2017

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GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib

2 October 2017

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The tumor suppressor Par-4 activates an extrinsic pathway for apoptosis

2 October 2017

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Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: sensitization by radiation and requirement for GRP78 and LRP1.

2 October 2017

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Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways

2 October 2017

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Ligation of cancer cell surface GRP78 with antibodies directed against its COOH-terminal domain up-regulates p53 activity and promotes apoptosis

2 October 2017

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GRP78: a multifunctional receptor on the cell surface

2 October 2017

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Glucose-regulated protein 78 (Grp78/BiP) is secreted by human oviduct epithelial cells and the recombinant protein modulates sperm-zona pellucida binding

2 October 2017

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Identification of proteins associating with glycosylphosphatidylinositol- anchored T-cadherin on the surface of vascular endothelial cells: role for Grp78/BiP in T-cadherin-dependent cell survival

2 October 2017

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Hypoxic inhibition of nonsense-mediated RNA decay regulates gene expression and the integrated stress response

2 October 2017

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A new tumor-specific variant of GRP78 as target for antibody-based therapy

2 October 2017

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Therapeutic angiogenesis of mouse hind limb ischemia by novel peptide activating GRP78 receptor on endothelial cells

2 October 2017

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GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth

2 October 2017

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Human cytomegalovirus specifically controls the levels of the endoplasmic reticulum chaperone BiP/GRP78, which is required for virion assembly

2 October 2017

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Phage display derived human monoclonal antibodies isolated by binding to the surface of live primary breast cancer cells recognize GRP78.

2 October 2017

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The role of p58IPK in protecting the stressed endoplasmic reticulum

2 October 2017

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2 October 2017

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Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery

2 October 2017

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Prostate cancer cell proliferation in vitro is modulated by antibodies against glucose-regulated protein 78 isolated from patient serum

2 October 2017

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Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand

2 October 2017

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The role of BiP in endoplasmic reticulum-associated degradation of major histocompatibility complex class I heavy chain induced by cytomegalovirus proteins.

2 October 2017

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Activation and cross-talk between Akt, NF-kappaB, and unfolded protein response signaling in 1-LN prostate cancer cells consequent to ligation of cell surface-associated GRP78.

2 October 2017

1 reference

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Identification of mammalian proteins cross-linked to DNA by ionizing radiation

2 October 2017

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Regulation of tissue factor--mediated initiation of the coagulation cascade by cell surface grp78.

2 October 2017

1 reference

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Kringle 5 of human plasminogen induces apoptosis of endothelial and tumor cells through surface-expressed glucose-regulated protein 78.

2 October 2017

1 reference

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Binding of activated alpha2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMK

2 October 2017

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Lipoptosis: tumor-specific cell death by antibody-induced intracellular lipid accumulation

2 October 2017

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Identification of GRP 78 (BiP) as a liver cell expressed receptor element for dengue virus serotype 2.

2 October 2017

1 reference

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Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation

2 October 2017

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2 October 2017

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Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function

2 October 2017

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2 October 2017

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GRP78, a coreceptor for coxsackievirus A9, interacts with major histocompatibility complex class I molecules which mediate virus internalization

2 October 2017

1 reference

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The glucose-regulated proteins: stress induction and clinical applications

2 October 2017

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Major histocompatibility class one molecule associates with glucose regulated protein (GRP) 78 on the cell surface

2 October 2017

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Identification and characterization of molecular interactions between glucose-regulated proteins (GRPs) mortalin/GRP75/peptide-binding protein 74 (PBP74) and GRP94.

2 October 2017

1 reference

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Histone H3 and heat shock protein GRP78 are selectively cross-linked to DNA by photoactivated gilvocarcin V in human fibroblasts

2 October 2017

1 reference

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Lead targets GRP78, a molecular chaperone, in C6 rat glioma cells

2 October 2017

1 reference

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KDEL proteins are found on the surface of NG108-15 cells

2 October 2017

1 reference

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A lymphocyte cell surface heat shock protein homologous to the endoplasmic reticulum chaperone, immunoglobulin heavy chain binding protein BIP.

2 October 2017

1 reference

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A C-terminal signal prevents secretion of luminal ER proteins

2 October 2017

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Human gene encoding the 78,000-dalton glucose-regulated protein and its pseudogene: structure, conservation, and regulation

2 October 2017

1 reference

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Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress.

2 October 2017

1 reference

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KDEL receptor expression is not coordinatedly up-regulated with ER stress-induced reticuloplasmin expression in HeLa cells.

11 July 2018

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Heavy chain binding protein (BiP/GRP78) and endoplasmin are exported from the endoplasmic reticulum in rat exocrine pancreatic cells, similar to protein disulfide-isomerase

11 July 2018

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Capsaicin-induced apoptosis in human hepatoma HepG2 cells.

11 July 2018

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Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders.

24 September 2018

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Decreased cell survival and DNA repair capacity after UVC irradiation in association with down-regulation of GRP78/BiP in human RSa cells

24 September 2018

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The role of MTJ-1 in cell surface translocation of GRP78, a receptor for alpha 2-macroglobulin-dependent signaling

24 September 2018

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A novel receptor function for the heat shock protein Grp78: silencing of Grp78 gene expression attenuates alpha2M*-induced signalling

24 September 2018

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The involvement of copper transporter in lead-induced oxidative stress in astroglia

24 September 2018

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12 December 2020

Localization of GRP78 to mitochondria under the unfolded protein response

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12 December 2020

Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands

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Selective upregulated expression of the alpha2-macroglobulin signaling receptor in highly metastatic 1-LN prostate carcinoma cells

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12 December 2020

Identifiers

DOI

10.1042/BJ20101569

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21309747%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21309747%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference