FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression (Q35965834)

11 August 2017

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression (English)

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11 August 2017

B Peck

2

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Almut Schulze

object named as

A Schulze

6

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author name string

E C Ferber

1

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11 August 2017

O Delpuech

3

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11 August 2017

G P Bell

4

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11 August 2017

P East

5

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11 August 2017

2 December 2011

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Cell Death & Differentiation

11 August 2017

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11 August 2017

19

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11 August 2017

968-979

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11 August 2017

6

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describes a project that uses

11 August 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3354049

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/cdd.2011.179

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cites work

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Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes

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Unravelling the tumor-suppressive functions of FOXO proteins

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Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo

2 October 2017

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PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a).

2 October 2017

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Mitochondrial complex III regulates hypoxic activation of HIF.

2 October 2017

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FOXO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2.

2 October 2017

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Stressing the role of FoxO proteins in lifespan and disease

2 October 2017

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HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

2 October 2017

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Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression

2 October 2017

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2 October 2017

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2 October 2017

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Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

2 October 2017

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Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation

2 October 2017

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Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis

2 October 2017

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Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins

2 October 2017

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The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

2 October 2017

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Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

2 October 2017

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A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

2 October 2017

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Mitochondrial defects in cancer

2 October 2017

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Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

2 October 2017

1 reference

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Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

2 October 2017

1 reference

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Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

2 October 2017

1 reference

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Direct control of the Forkhead transcription factor AFX by protein kinase B

2 October 2017

1 reference

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354049

beta-catenin is a target for the ubiquitin-proteasome pathway

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354049

Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354049

Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354049

Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354049

24 September 2018

Identifiers

DOI

10.1038/CDD.2011.179

1 reference

11 August 2017

1 reference

11 August 2017

1 reference