THZ1 Reveals Roles for Cdk7 in Co-transcriptional Capping and Pausing (Q35987692)

11 August 2017

THZ1 Reveals Roles for Cdk7 in Co-transcriptional Capping and Pausing (English)

1 reference

11 August 2017

7

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31 May 2020

author name string

Kyle A Nilson

1

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31 May 2020

Jiannan Guo

2

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31 May 2020

Michael E Turek

3

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31 May 2020

John E Brogie

4

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31 May 2020

Elizabeth Delaney

5

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31 May 2020

Donal S Luse

6

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31 May 2020

language of work or name

1 reference

5 August 2015

1 reference

11 August 2017

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31 May 2020

volume

59

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31 May 2020

issue

4

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31 May 2020

page(s)

576-587

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Architecture of the RNA polymerase II-Mediator core initiation complex

31 May 2020

cites work

1 reference

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Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor

2 October 2017

1 reference

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CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer.

2 October 2017

1 reference

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Fission yeast RNA triphosphatase reads an Spt5 CTD code

2 October 2017

1 reference

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Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells.

2 October 2017

1 reference

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Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

2 October 2017

1 reference

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Rtr1 Is a Dual Specificity Phosphatase That Dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD

2 October 2017

1 reference

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How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes

2 October 2017

1 reference

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RNA polymerase II transcription elongation and Pol II CTD Ser2 phosphorylation: A tail of two kinases

2 October 2017

1 reference

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TFIIH phosphorylation of the Pol II CTD stimulates mediator dissociation from the preinitiation complex and promoter escape.

2 October 2017

1 reference

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Kin28 regulates the transient association of Mediator with core promoters

2 October 2017

1 reference

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Release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription.

2 October 2017

1 reference

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Coupling mRNA processing with transcription in time and space.

2 October 2017

1 reference

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The Mediator complex and transcription regulation

2 October 2017

1 reference

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RNA polymerase II transcription elongation control

2 October 2017

1 reference

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The CDK Network: Linking Cycles of Cell Division and Gene Expression

2 October 2017

1 reference

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Transcription elongation factors DSIF and NELF: promoter-proximal pausing and beyond

2 October 2017

1 reference

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Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II

2 October 2017

1 reference

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Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546572

Functional association of Gdown1 with RNA polymerase II poised on human genes

2 October 2017

1 reference

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The initiation factor TFE and the elongation factor Spt4/5 compete for the RNAP clamp during transcription initiation and elongation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546572

Structural Insights to How Mammalian Capping Enzyme Reads the CTD Code

2 October 2017

1 reference

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A history of TFIIH: two decades of molecular biology on a pivotal transcription/repair factor.

2 October 2017

1 reference

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Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity

2 October 2017

1 reference

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CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

2 October 2017

1 reference

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Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex

2 October 2017

1 reference

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c-Myc regulates transcriptional pause release

2 October 2017

1 reference

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Separable functions of the fission yeast Spt5 carboxyl-terminal domain (CTD) in capping enzyme binding and transcription elongation overlap with those of the RNA polymerase II CTD

2 October 2017

1 reference

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TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II

2 October 2017

1 reference

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Phosphorylation of the RNA polymerase II C-terminal domain by TFIIH kinase is not essential for transcription of Saccharomyces cerevisiae genome

2 October 2017

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Isolation and functional analysis of RNA polymerase II elongation complexes.

2 October 2017

1 reference

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Analysis of factor interactions with RNA polymerase II elongation complexes using a new electrophoretic mobility shift assay

2 October 2017

1 reference

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Properties of RNA polymerase II elongation complexes before and after the P-TEFb-mediated transition into productive elongation.

2 October 2017

1 reference

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Chemical inhibition of the TFIIH-associated kinase Cdk7/Kin28 does not impair global mRNA synthesis.

2 October 2017

1 reference

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Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II

2 October 2017

1 reference

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Cdk7 is required for full activation of Drosophila heat shock genes and RNA polymerase II phosphorylation in vivo

2 October 2017

1 reference

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Tat stimulates cotranscriptional capping of HIV mRNA.

2 October 2017

1 reference

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A highly purified RNA polymerase II elongation control system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546572

Transcription elongation factor hSPT5 stimulates mRNA capping

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546572

Distinct roles for CTD Ser-2 and Ser-5 phosphorylation in the recruitment and allosteric activation of mammalian mRNA capping enzyme

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546572

Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546572

mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546572

5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546572

Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II

2 October 2017

1 reference

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Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase

2 October 2017

1 reference

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In vivo transcriptional pausing and cap formation on three Drosophila heat shock genes

2 October 2017

1 reference

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Requirement for TFIIH kinase activity in transcription by RNA polymerase II

2 October 2017

1 reference

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Promoter-proximal pausing by RNA polymerase II in vitro: transcripts shorter than 20 nucleotides are not capped

2 October 2017

1 reference

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Molecular Basis of Transcription-Coupled Pre-mRNA Capping

2 October 2017

1 reference

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Deciphering the RNA polymerase II CTD code in fission yeast

11 July 2018

1 reference

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Structure and mechanism of RNA polymerase II CTD phosphatases

11 July 2018

1 reference

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Analysis of RNA polymerase II elongation in vitro.

24 September 2018

1 reference

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Functional coupling of capping and transcription of mRNA.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546572

Interactions between fission yeast mRNA capping enzymes and elongation factor Spt5.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546572

A universal RNA polymerase II CTD cycle is orchestrated by complex interplays between kinase, phosphatase, and isomerase enzymes along genes

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26257281

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2015.06.032

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26257281%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26257281%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference