Identification of a tumour suppressor network opposing nuclear Akt function (Q35991130)

11 August 2017

Identification of a tumour suppressor network opposing nuclear Akt function (English)

1 reference

11 August 2017

6

Pier Paolo Pandolfi

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Carlos Cordon-Cardo

series ordinal

5

object named as

Carlos Cordon-Cardo

1 reference

11 August 2017

2

Andrea Alimonti

1 reference

11 August 2017

1

Lloyd C Trotman

1 reference

11 August 2017

4

Jason A Koutcher

1 reference

11 August 2017

3

Pier Paolo Scaglioni

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PMCID

1976603

11 August 2017

language of work or name

English

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publication date

7 May 2006

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11 August 2017

5

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inferred from page(s)

published in

Nature

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11 August 2017

441

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11 August 2017

7092

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11 August 2017

523-527

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https://scigraph.springernature.com/pub.10.1038/nature04809

11 August 2017

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cites work

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

PP2A: the expected tumor suppressor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Advances in protein kinase B signalling: AKTion on multiple fronts

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Loss of the tumor suppressor PML in human cancers of multiple histologic origins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Pten dose dictates cancer progression in the prostate

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

FoxO3a eggs on fertility and aging

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Targeting the PI3K-Akt pathway in human cancer: rationale and promise

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

The many forks in FOXO's road

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

The role of PML in tumor suppression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

PTEN and myotubularin: novel phosphoinositide phosphatases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

The function of PML in p53-dependent apoptosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

2 October 2017

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Regulation of protein kinase cascades by protein phosphatase 2A.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

PML is essential for multiple apoptotic pathways

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

Pten is essential for embryonic development and tumour suppression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976603

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

2 October 2017

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE04809

Molecular mechanisms of prostate cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16680151

12 December 2020

inferred from PubMed ID database lookup

Impaired Fas response and autoimmunity in Pten+/- mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16680151

12 December 2020

inferred from PubMed ID database lookup

Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16680151

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NATURE04809

1 reference

PMCID

1976603

Dimensions Publication ID

11 August 2017

0 references

1 reference

11 August 2017

1 reference

PMCID

1976603