Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis (Q24681977)

12

0 references

Lloyd Trotman

2

Lloyd C Trotman

0 references

Zhenbang Chen

1

Zhenbang Chen

0 references

Hui-Kuan Lin

4

Hui-Kuan Lin

0 references

David W. Shaffer

3

David Shaffer

0 references

Zohar A Dotan

5

Zohar A Dotan

0 references

Masaru Niki

6

Masaru Niki

0 references

Jason A Koutcher

7

Jason A Koutcher

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author name string

Howard I Scher

8

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Thomas Ludwig

9

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William Gerald

Pten dose dictates cancer progression in the prostate

10

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language of work or name

English

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publication date

4 August 2005

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published in

Nature

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volume

436

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page(s)

725-30

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issue

7051

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cites work

1 reference

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

7 April 2017

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

7 April 2017

1 reference

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7 April 2017

Surfing the p53 network

1 reference

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Role of the proto-oncogene Pokemon in cellular transformation and ARF repression

7 April 2017

1 reference

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PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

7 April 2017

1 reference

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Regulation of PTEN transcription by p53

7 April 2017

1 reference

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Intrinsic tumour suppression

7 April 2017

1 reference

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Cancer mortality surveillance--United States, 1990-2000.

28 September 2017

1 reference

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Loss of a small region around the PTEN locus is a major chromosome 10 alteration in prostate cancer xenografts and cell lines

28 September 2017

1 reference

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Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway

28 September 2017

1 reference

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Conditional mouse models of sporadic cancer

28 September 2017

1 reference

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Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

28 September 2017

1 reference

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HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

28 September 2017

1 reference

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Putting the stress on senescence

28 September 2017

1 reference

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Cellular senescence as a tumor-suppressor mechanism

28 September 2017

1 reference

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A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

28 September 2017

1 reference

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Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation

28 September 2017

1 reference

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Molecular genetics of prostate cancer.

28 September 2017

1 reference

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The multiple roles of PTEN in tumor suppression

28 September 2017

1 reference

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The cat and mouse games that genes, viruses, and cells play

28 September 2017

1 reference

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Leveling of prostate cancer mortality in Western Europe

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1939938

PTEN/MMAC1 mutations in prostate cancer.

28 November 2018

1 reference

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Loss of p53 and c-myc overrepresentation in stage T(2-3)N(1-3)M(0) prostate cancer are potential markers for cancer progression

28 November 2018

1 reference

12 December 2020

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

1 reference

12 December 2020

Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues

1 reference

12 December 2020

p53 mutations in prostate cancer bone metastases suggest that selected p53 mutants in the primary site define foci with metastatic potential

1 reference

12 December 2020

Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse

1 reference

12 December 2020

PTEN and p53: who will get the upper hand?

1 reference

12 December 2020

Analysis of PTEN and the 10q23 region in primary prostate carcinomas

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE03918

1 reference

Dimensions Publication ID

968449

1027424701

0 references

968449

1 reference

1 reference

1 reference