T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin (Q36011042)

11 August 2017

T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin (English)

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11 August 2017

M Congia

1

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author name string

S Patel

2

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11 August 2017

A P Cope

3

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11 August 2017

S De Virgiliis

4

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11 August 2017

G Sønderstrup

5

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11 August 2017

language of work or name

English

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publication date

1 March 1998

1 reference

Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

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11 August 2017

95

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11 August 2017

3833-3838

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11 August 2017

7

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Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101,beta1*0401) transgenic mice.

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

Cellular immune response to diverse islet cell antigens in IDDM.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

A genome-wide search for human type 1 diabetes susceptibility genes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

Expression of HLA-DR4 and human CD4 transgenes in mice determines the variable region beta-chain T-cell repertoire and mediates an HLA-DR-restricted immune response

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

Lawrence Lecture. The Emperor's new genes: 1993 RD Lawrence Lecture

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

MHC ligands and peptide motifs: first listing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

Peptide binding specificity of HLA-DR4 molecules: correlation with rheumatoid arthritis association

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

Experimental autoimmune insulitis. Induction by T lymphocytes specific for a peptide of proinsulin.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

Patterns of amino acids near signal-sequence cleavage sites

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

HLA and Disease 1982 - A Survey

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

HLA DR antigens and susceptibility to insulin-dependent diabetes mellitus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

A diabetes-susceptible HLA haplotype is best defined by a combination of HLA-DR and -DQ alleles

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

A combination of HLA-DQ beta Asp57-negative and HLA DQ alpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

Mice lacking MHC class II molecules

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

Insulin autoimmunity: the rate limiting factor in pre-type I diabetes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

HLA class II alleles and susceptibility and resistance to insulin dependent diabetes mellitus in Mexican-American families

11 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.7.3833

Molecular basis of Thomsen's disease (autosomal dominant myotonia congenita).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.7.3833

IDDM2-VNTR-encoded susceptibility to type 1 diabetes: dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.7.3833

Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.7.3833

Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19923

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

23 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.7.3833

A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.7.3833

Combinations of specific DRB1, DQA1, DQB1 haplotypes are associated with insulin-dependent diabetes mellitus in Sardinia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.7.3833

The distribution of DR4 haplotypes in Sardinia suggests a primary association of type I diabetes with DRB1 and DQB1 loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.7.3833

Specific association of HLA-DR4 with increased prevalence and level of insulin autoantibodies in first-degree relatives of patients with type I diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.7.3833

HLA-associated insulin autoantibody formation in newly diagnosed type I diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.7.3833

Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.7.3833

21 January 2018

Identifiers

DOI

10.1073/PNAS.95.7.3833

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11 August 2017

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1 reference

11 August 2017

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