FGFR1 cleavage and nuclear translocation regulates breast cancer cell behavior (Q36027395)

11 August 2017

FGFR1 cleavage and nuclear translocation regulates breast cancer cell behavior (English)

1 reference

11 August 2017

1 reference

Athina-Myrto Chioni

1

1 reference

11 August 2017

Richard Grose

series ordinal

2

1 reference

11 August 2017

language of work or name

English

0 references

publication date

4 June 2012

1 reference

11 August 2017

17

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inferred from page(s)

published in

Journal of Cell Biology

1 reference

11 August 2017

197

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11 August 2017

6

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11 August 2017

801-817

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describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3373409/fullTextXML

inferred from PubMed Central ID database lookup

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Fibroblast growth factor receptor-1 (FGFR1) nuclear dynamics reveal a novel mechanism in transcription control

2 October 2017

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Combined gene expression analysis of whole-tissue and microdissected pancreatic ductal adenocarcinoma identifies genes specifically overexpressed in tumor epithelia.

2 October 2017

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2 October 2017

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Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer

2 October 2017

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Trafficking of receptor tyrosine kinases to the nucleus

2 October 2017

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2 October 2017

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2 October 2017

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FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis

2 October 2017

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FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas

2 October 2017

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Notch signalling: a simple pathway becomes complex

2 October 2017

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Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis

2 October 2017

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Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family

2 October 2017

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Nuclear translocation of cell-surface receptors: lessons from fibroblast growth factor

2 October 2017

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A novel polyclonal antibody specific for the Na(v)1.5 voltage-gated Na(+) channel 'neonatal' splice form

2 October 2017

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Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway

2 October 2017

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Mechanisms underlying differential responses to FGF signaling

2 October 2017

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Cellular signaling by fibroblast growth factor receptors

2 October 2017

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Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin.

2 October 2017

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Development of a quantitative method to analyse tumour cell invasion in organotypic culture

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer.

2 October 2017

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Regulation of endocytosis, nuclear translocation, and signaling of fibroblast growth factor receptor 1 by E-cadherin

2 October 2017

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Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2

2 October 2017

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90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling

2 October 2017

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Spatial and temporal patterns of ERK signaling during mouse embryogenesis

2 October 2017

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Expression of endogenous granzyme B in a subset of human primary breast carcinomas

2 October 2017

1 reference

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Nuclear trafficking of FGFR1: a role for the transmembrane domain

2 October 2017

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A nuclear form of the heparin-binding epidermal growth factor-like growth factor precursor is a feature of aggressive transitional cell carcinoma.

2 October 2017

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Vesicle transmembrane potential is required for translocation to the cytosol of externally added FGF-1.

2 October 2017

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

2 October 2017

1 reference

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Regulation of G(1) cell-cycle progression by oncogenes and tumor suppressor genes

2 October 2017

1 reference

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Nuclear localization of EGF receptor and its potential new role as a transcription factor

2 October 2017

1 reference

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Fibroblast growth factors

2 October 2017

1 reference

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Importin beta-mediated nuclear import of fibroblast growth factor receptor: role in cell proliferation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Novel nuclear signaling pathway mediates activation of fibroblast growth factor-2 gene by type 1 and type 2 angiotensin II receptors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Structural characterization of the circulating soluble FGF receptors reveals multiple isoforms generated by secretion and ectodomain shedding

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Nuclear accumulation of fibroblast growth factor receptors is regulated by multiple signals in adrenal medullary cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Nuclear Translocation of fibroblast growth factor (FGF) receptors in response to FGF-2.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Nuclear localization of p185neu tyrosine kinase and its association with transcriptional transactivation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Cloning of cDNA for the glutamate-binding subunit of an NMDA receptor complex

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Ligand dependent and independent internalization and nuclear translocation of fibroblast growth factor (FGF) receptor 1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Dual mode of signal transduction by externally added acidic fibroblast growth factor

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Reaction of serine proteases with substituted isocoumarins: discovery of 3,4-dichloroisocoumarin, a new general mechanism based serine protease inhibitor

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373409

Control of CREB-binding protein signaling by nuclear fibroblast growth factor receptor-1: a novel mechanism of gene regulation

11 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201108077

The serine protease marapsin is expressed in stratified squamous epithelia and is up-regulated in the hyperproliferative epidermis of psoriasis and regenerating wounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201108077

Elements controlling the expression and induction of the skin hyperproliferation-associated keratin K6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201108077

Integrative nuclear FGFR1 signaling (INFS) pathway mediates activation of the tyrosine hydroxylase gene by angiotensin II, depolarization and protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201108077

In vitro invasiveness of DU-145 human prostate carcinoma cells is modulated by EGF receptor-mediated signals

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22665522

12 December 2020

inferred from PubMed ID database lookup

Nuclear localization of functional FGF receptor 1 in human astrocytes suggests a novel mechanism for growth factor action

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22665522

12 December 2020

inferred from PubMed ID database lookup

Altered intracellular localization of fibroblast growth factor receptor 3 in human breast cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22665522

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1083/JCB.201108077

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

22665522

1 reference