MEK guards proteome stability and inhibits tumor-suppressive amyloidogenesis via HSF1. (Q36041862)

11 August 2017

MEK guards proteome stability and inhibits tumor-suppressive amyloidogenesis via HSF1. (English)

1 reference

11 August 2017

Zijian Tang

1

1 reference

11 August 2017

Siyuan Dai

2

1 reference

11 August 2017

Yishu He

3

1 reference

11 August 2017

Rosalinda A Doty

4

1 reference

11 August 2017

Leonard D Shultz

5

1 reference

11 August 2017

Stephen Byers Sampson

6

1 reference

11 August 2017

Chengkai Dai

7

1 reference

11 August 2017

language of work or name

English

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publication date

1 February 2015

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11 August 2017

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11 August 2017

160

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11 August 2017

4

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11 August 2017

729-744

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describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4564124/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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HSP90 at the hub of protein homeostasis: emerging mechanistic insights

2 October 2017

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A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.

2 October 2017

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2 October 2017

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Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

2 October 2017

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Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

2 October 2017

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Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis

2 October 2017

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MAP kinase signalling pathways in cancer

2 October 2017

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2 October 2017

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Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor

2 October 2017

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Protein misfolding, functional amyloid, and human disease

2 October 2017

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Identification of a selective ERK inhibitor and structural determination of the inhibitor-ERK2 complex

2 October 2017

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Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress

2 October 2017

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2 October 2017

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Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures

2 October 2017

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2 October 2017

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The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

2 October 2017

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Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

2 October 2017

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2 October 2017

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HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice

2 October 2017

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2 October 2017

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Growth factor-stimulated MAP kinase induces rapid retrophosphorylation and inhibition of MAP kinase kinase (MEK1)

2 October 2017

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2 October 2017

The heat-shock response

1 reference

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Transcriptional activity of heat shock factor 1 at 37 degrees C is repressed through phosphorylation on two distinct serine residues by glycogen synthase kinase 3 and protein kinases Calpha and Czeta

2 October 2017

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11 July 2018

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Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase

11 July 2018

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A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal

11 July 2018

1 reference

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The effect of ionic strength on the UV-vis spectrum of congo red in aqueous solution.

23 September 2018

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Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.

23 September 2018

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Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564124

Selective suppression of lymphomas by functional loss of Hsf1 in a p53-deficient mouse model for spontaneous tumors

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25679764

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increasing the dynamic range of in situ PLA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25679764

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2015.01.028

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

25679764

1 reference