Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma. (Q39422587)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

Stilianos Antonarakis

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Christian Iseli

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Armand Valsesia

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Jacques S Beckmann

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Ioannis Xenarios

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Victor Jongeneel

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

5

Daniel Robyr

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

11

Olivier Michielin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Sergey I Nikolaev

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Donata Rimoldi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Corinne Gehrig

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Keith Harshman

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Michel Guipponi

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Olesya Bukach

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Vincent Zoete

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Katja Muehlethaler

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Daniel Speiser

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Thanos D Halazonetis

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Brian J Stevenson

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

25 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

133-139

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

19 January 2020

0 references

0 references

0 references

0 references

0 references

0 references

0 references

https://scigraph.springernature.com/pub.10.1038/ng.1026

0 references

1 reference

Mutations of the BRAF gene in human cancer

21 January 2018

1 reference

Malignant melanoma: genetics and therapeutics in the genomic era.

21 January 2018

1 reference

A comprehensive catalogue of somatic mutations from a human cancer genome

21 January 2018

1 reference

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

21 January 2018

1 reference

DNA repair in mammalian cells : Nucleotide excision repair: variations on versatility

21 January 2018

1 reference

Role of DNA damage-induced replication checkpoint in promoting lesion bypass by translesion synthesis in yeast.

21 January 2018

1 reference

Network-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma

21 January 2018

1 reference

The MAPK pathway in melanoma

21 January 2018

1 reference

Identification of a novel mitogen-activated protein kinase kinase activation domain recognized by the inhibitor PD 184352.

21 January 2018

1 reference

Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD).

21 January 2018

1 reference

Noonan and cardio-facio-cutaneous syndromes: two clinically and genetically overlapping disorders.

21 January 2018

1 reference

MEK1 mutations confer resistance to MEK and B-RAF inhibition

21 January 2018

1 reference

Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome

21 January 2018

1 reference

Crystal structures of MEK1 binary and ternary complexes with nucleotides and inhibitors

21 January 2018

1 reference

Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.

21 January 2018

1 reference

BRAF alterations are associated with complex mutational profiles in malignant melanoma

21 January 2018

1 reference

Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence

21 January 2018

1 reference

Genome remodelling in a basal-like breast cancer metastasis and xenograft

21 January 2018

1 reference

Recurring mutations found by sequencing an acute myeloid leukemia genome

21 January 2018

1 reference

A small-cell lung cancer genome with complex signatures of tobacco exposure

21 January 2018

1 reference

Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis

21 January 2018

1 reference

A method and server for predicting damaging missense mutations

21 January 2018

1 reference

BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair

21 January 2018

1 reference

Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

21 January 2018

1 reference

Hdac3 is essential for the maintenance of chromatin structure and genome stability

21 January 2018

1 reference

Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development

21 January 2018

1 reference

Identification of Fat4 as a candidate tumor suppressor gene in breast cancers

21 January 2018

1 reference

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

21 January 2018

1 reference

Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma

21 January 2018

1 reference

Somatic mutations affect key pathways in lung adenocarcinoma

21 January 2018

1 reference

Low-density lipoprotein receptor family: endocytosis and signal transduction

21 January 2018

1 reference

The low-density lipoprotein receptor-related protein 10 is a negative regulator of the canonical Wnt/beta-catenin signaling pathway

21 January 2018

1 reference

Epigenetic silencing of DSC3 is a common event in human breast cancer

21 January 2018

1 reference

Normal human melanocyte homeostasis as a paradigm for understanding melanoma

21 January 2018

1 reference

The consensus coding sequences of human breast and colorectal cancers

21 January 2018

1 reference

Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma

21 January 2018

1 reference

Mapping short DNA sequencing reads and calling variants using mapping quality scores

21 January 2018

1 reference

Indexing strategies for rapid searches of short words in genome sequences.

21 January 2018

1 reference

Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads

21 January 2018

1 reference

CHARMM: the biomolecular simulation program

21 January 2018

1 reference

UCSF Chimera--a visualization system for exploratory research and analysis

21 January 2018

1 reference

How melanomas bypass new therapy

21 January 2018

1 reference

Dermatological findings in 61 mutation-positive individuals with cardiofaciocutaneous syndrome

21 January 2018

1 reference

12 December 2020

The Catalogue of Somatic Mutations in Cancer (COSMIC)

1 reference

12 December 2020

LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines

1 reference

12 December 2020

Mutations in the neurofibromatosis 1 gene in sporadic malignant melanoma cell lines

1 reference

12 December 2020

Further delineation of the phenotype resulting from BRAF or MEK1 germline mutations helps differentiate cardio-facio-cutaneous syndrome from Costello syndrome

1 reference

12 December 2020

Identifiers

DOI

10.1038/NG.1026

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22197931%20AND%20SRC:MED&resulttype=core&format=json

release_u2y6bf66sbfnrpas5lql5b5k7a

19 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/u2y6bf66sbfnrpas5lql5b5k7a

24 November 2022

mapped directly with Wikidata item

1 reference