Endoglin regulates PI3-kinase/Akt trafficking and signaling to alter endothelial capillary stability during angiogenesis (Q36066614)

12 August 2017

Endoglin regulates PI3-kinase/Akt trafficking and signaling to alter endothelial capillary stability during angiogenesis (English)

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12 August 2017

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5

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12 August 2017

Arun Sharma

4

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Christelle Golzio

object named as

Christelle Golzio

series ordinal

2

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Gerard C Blobe

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6

object named as

Gerard C Blobe

1 reference

12 August 2017

Nam Y Lee

1

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PMCID

3386206

12 August 2017

Catherine E Gatza

series ordinal

3

1 reference

12 August 2017

16 May 2012

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Molecular Biology of the Cell

12 August 2017

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12 August 2017

23

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13

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12 August 2017

2412-2423

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PMCID

3386206

describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3386206/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The TGF-beta co-receptor endoglin modulates the expression and transforming potential of H-Ras

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Signaling by members of the TGF-beta family in vascular morphogenesis and disease

2 October 2017

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Functional analyses of variants reveal a significant role for dominant negative and common alleles in oligogenic Bardet-Biedl syndrome

2 October 2017

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Role of extracellular signal-regulated kinase and AKT cascades in regulating hypoxia-induced angiogenic factors produced by a trophoblast-derived cell line

2 October 2017

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Casein kinase 2beta as a novel enhancer of activin-like receptor-1 signaling

2 October 2017

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Emerging role of bone morphogenetic proteins in angiogenesis

2 October 2017

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Hypertension produced by placental ischemia in pregnant rats is associated with increased soluble endoglin expression

2 October 2017

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Mechanisms controlling human endothelial lumen formation and tube assembly in three-dimensional extracellular matrices

2 October 2017

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Novel biochemical pathways of endoglin in vascular cell physiology.

2 October 2017

1 reference

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ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2

2 October 2017

1 reference

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The interaction of endoglin with beta-arrestin2 regulates transforming growth factor-beta-mediated ERK activation and migration in endothelial cells

2 October 2017

1 reference

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Regulation of class IA PI3Ks: is there a role for monomeric PI3K subunits?

2 October 2017

1 reference

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Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells

2 October 2017

1 reference

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Endoglin null endothelial cells proliferate faster and are more responsive to transforming growth factor beta1 with higher affinity receptors and an activated Alk1 pathway

2 October 2017

1 reference

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Type I transforming growth factor beta receptor binds to and activates phosphatidylinositol 3-kinase.

2 October 2017

1 reference

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Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

Endoglin regulates cytoskeletal organization through binding to ZRP-1, a member of the Lim family of proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

Endoglin controls cell migration and composition of focal adhesions: function of the cytosolic domain

2 October 2017

1 reference

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

2 October 2017

1 reference

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Endoglin (CD105): a powerful therapeutic target on tumor-associated angiogenetic blood vessels

2 October 2017

1 reference

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

2 October 2017

1 reference

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Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels.

2 October 2017

1 reference

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Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptor

2 October 2017

1 reference

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A murine model of hereditary hemorrhagic telangiectasia

2 October 2017

1 reference

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Defective angiogenesis in mice lacking endoglin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

Endoglin modulates cellular responses to TGF-beta 1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

Genetic abnormalities in hereditary hemorrhagic telangiectasia.

2 October 2017

1 reference

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Crosstalk between PTEN/Akt2 and TGFbeta signaling involving EGF receptor down-regulation during the tumor promotion process from the early stage in a rat two-stage hepatocarcinogenesis model

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

Tube formation: an in vitro matrigel angiogenesis assay.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

Endoglin promotes transforming growth factor beta-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

Functional analysis of mutations in the kinase domain of the TGF-beta receptor ALK1 reveals different mechanisms for induction of hereditary hemorrhagic telangiectasia

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

Blood outgrowth endothelial cells from Hereditary Haemorrhagic Telangiectasia patients reveal abnormalities compatible with vascular lesions

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

Reconstitution of phosphoinositide 3-kinase-dependent insulin signaling in a cell-free system

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

CD105 antagonizes the inhibitory signaling of transforming growth factor beta1 on human vascular endothelial cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386206

Pathogenesis of Arteriovenous Malformations in the Absence of Endoglin

21 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22593212

12 December 2020

inferred from PubMed ID database lookup

Six novel mutations in the endoglin gene in hereditary hemorrhagic telangiectasia type 1 suggest a dominant-negative effect of receptor function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22593212

12 December 2020

inferred from PubMed ID database lookup

Reduced angiogenic responses in adult Endoglin heterozygous mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22593212

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1091/MBC.E11-12-0993

1 reference

12 August 2017

1 reference

12 August 2017

1 reference

PMCID

3386206