Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase. (Q36078757)

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English	Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase.	scientific article

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31 January 2020

Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase (English)

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31 January 2020

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Juliana Camacho-Pereira

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31 January 2020

Eduardo N. Chini

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Eduardo N Chini

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Veronica Nin

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Carlos Escande

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Claudia C Chini

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Shailendra Giri

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Jonathan Matalonga

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Zhenkun Lou

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2 May 2012

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Journal of Biological Chemistry

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23489-23501

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31 January 2020

Regulation of SIRT1 activity by genotoxic stress

1 reference

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Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases

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The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).

1 reference

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Targeting sirtuin 1 to improve metabolism: all you need is NAD(+)?

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2 October 2017

Peptide switch is essential for Sirt1 deacetylase activity

1 reference

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2 October 2017

Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction

1 reference

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Rimonabant, a cannabinoid receptor type 1 inverse agonist, inhibits hepatocyte lipogenesis by activating liver kinase B1 and AMP-activated protein kinase axis downstream of Gα i/o inhibition

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2 October 2017

Franklin H. Epstein Lecture: Sirtuins, aging, and medicine

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2 October 2017

Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity

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2 October 2017

HDAC3 is negatively regulated by the nuclear protein DBC1

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2 October 2017

Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation

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Shear stress, SIRT1, and vascular homeostasis

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DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1

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2 October 2017

Identification of DBC1 as a transcriptional repressor for BRCA1

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2 October 2017

Mammalian sirtuins: biological insights and disease relevance

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2 October 2017

Repression of estrogen receptor beta function by putative tumor suppressor DBC1

1 reference

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2 October 2017

Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice

1 reference

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2 October 2017

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

1 reference

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2 October 2017

JNK1 phosphorylates SIRT1 and promotes its enzymatic activity

1 reference

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2 October 2017

PKA phosphorylates and inactivates AMPKalpha to promote efficient lipolysis

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2 October 2017

Resveratrol is not a direct activator of SIRT1 enzyme activity

1 reference

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2 October 2017

CK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage

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2 October 2017

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

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2 October 2017

Carboxy-terminal phosphorylation of SIRT1 by protein kinase CK2

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CD38 as a regulator of cellular NAD: a novel potential pharmacological target for metabolic conditions

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Deleted in breast cancer 1, a novel androgen receptor (AR) coactivator that promotes AR DNA-binding activity

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2 October 2017

Phosphorylation regulates SIRT1 function.

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2 October 2017

A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

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The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control

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A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism

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2 October 2017

Tissue-specific regulation of SIRT1 by calorie restriction

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2 October 2017

Pharmacological PKA inhibition: all may not be what it seems

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AMPK phosphorylation of raptor mediates a metabolic checkpoint

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2 October 2017

Negative regulation of the deacetylase SIRT1 by DBC1

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2 October 2017

DBC1 is a negative regulator of SIRT1

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SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress

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2 October 2017

The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor

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2 October 2017

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Modulation of estrogen receptor alpha protein level and survival function by DBC-1.

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Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

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Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

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Mechanism of human SIRT1 activation by resveratrol

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Similar substrate recognition motifs for mammalian AMP-activated protein kinase, higher plant HMG-CoA reductase kinase-A, yeast SNF1, and mammalian calmodulin-dependent protein kinase I

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Exercise-induced alterations in extracellular signal-regulated kinase 1/2 and mammalian target of rapamycin (mTOR) signalling to regulatory mechanisms of mRNA translation in mouse muscle

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Regulation of SIRT 1 mediated NAD dependent deacetylation: a novel role for the multifunctional enzyme CD38

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Extension of human cell lifespan by nicotinamide phosphoribosyltransferase

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Identifiers

10.1074/JBC.M112.365874

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31 January 2020

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31 January 2020

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