Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples. (Q36101151)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21210717%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples (English)

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19 January 2020

7

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19 January 2020

author name string

Sophie Lachapelle

1

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19 January 2020

Jean-Philippe Gagné

2

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19 January 2020

Chantal Garand

3

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19 January 2020

Myriam Desbiens

4

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19 January 2020

Yan Coulombe

5

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19 January 2020

Vilhelm A Bohr

6

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19 January 2020

Jean-Yves Masson

8

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19 January 2020

Guy G Poirier

9

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19 January 2020

Michel Lebel

10

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19 January 2020

publication date

16 February 2011

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Journal of Proteome Research

19 January 2020

published in

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19 January 2020

volume

10

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19 January 2020

issue

3

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19 January 2020

page(s)

1216-1227

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Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination

19 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Expression profiling of mouse embryonic fibroblasts with a deletion in the helicase domain of the Werner Syndrome gene homologue treated with hydrogen peroxide

2 October 2017

1 reference

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Vitamin C restores healthy aging in a mouse model for Werner syndrome

2 October 2017

1 reference

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The interaction profile of homologous recombination repair proteins RAD51C, RAD51D and XRCC2 as determined by proteomic analysis

2 October 2017

1 reference

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The Werner syndrome protein affects the expression of genes involved in adipogenesis and inflammation in addition to cell cycle and DNA damage responses.

2 October 2017

1 reference

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Cornelia de Lange syndrome mutations in SMC1A or SMC3 affect binding to DNA

2 October 2017

1 reference

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Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks

2 October 2017

1 reference

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PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites

2 October 2017

1 reference

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Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors

2 October 2017

1 reference

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The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1

2 October 2017

1 reference

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Werner syndrome protein interacts functionally with translesion DNA polymerases

2 October 2017

1 reference

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Translocation of human ribosomal protein S3 to sites of DNA damage is dependant on ERK-mediated phosphorylation following genotoxic stress

2 October 2017

1 reference

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Werner syndrome protein prevents DNA breaks upon chromatin structure alteration

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Mismatch repair factor MSH2-MSH3 binds and alters the conformation of branched DNA structures predicted to form during genetic recombination

2 October 2017

1 reference

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The high binding affinity of human ribosomal protein S3 to 7,8-dihydro-8-oxoguanine is abrogated by a single amino acid change

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Collaboration of Werner syndrome protein and BRCA1 in cellular responses to DNA interstrand cross-links

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Formation of a nuclear complex containing the p53 tumor suppressor, YB-1, and the Werner syndrome gene product in cells treated with UV light

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Nuclear deformation characterizes Werner syndrome cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Current advances in unraveling the function of the Werner syndrome protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Cornelia de Lange Syndrome and the link between chromosomal function, DNA repair and developmental gene regulation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Characterization of a wide range base-damage-endonuclease activity of mammalian rpS3

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

NIPBL, encoding a homolog of fungal Scc2-type sister chromatid cohesion proteins and fly Nipped-B, is mutated in Cornelia de Lange syndrome

2 October 2017

1 reference

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A statistical model for identifying proteins by tandem mass spectrometry

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Central Role for the Werner Syndrome Protein/Poly(ADP-Ribose) Polymerase 1 Complex in the Poly(ADP-Ribosyl)ation Pathway after DNA Damage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Gene expression profiling in Werner syndrome closely resembles that of normal aging

2 October 2017

1 reference

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WRN interacts physically and functionally with the recombination mediator protein RAD52

2 October 2017

1 reference

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Mouse telomere analysis using an optimized primed in situ (PRINS) labeling technique

2 October 2017

1 reference

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Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice

2 October 2017

1 reference

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The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein

2 October 2017

1 reference

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Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search

2 October 2017

1 reference

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Homologous recombination resolution defect in werner syndrome

2 October 2017

1 reference

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Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Loss of Werner syndrome protein function promotes aberrant mitotic recombination

2 October 2017

1 reference

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Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Functional interaction between Ku and the werner syndrome protein in DNA end processing

2 October 2017

1 reference

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Ku complex interacts with and stimulates the Werner protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Functional interaction between the Werner Syndrome protein and DNA polymerase delta

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Enzymatic and DNA binding properties of purified WRN protein: high affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

The Werner syndrome protein is involved in RNA polymerase II transcription

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Functional and physical interaction between WRN helicase and human replication protein A

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virus

2 October 2017

1 reference

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RecQ DNA helicase is a suppressor of illegitimate recombination in Escherichia coli

2 October 2017

1 reference

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Telomere length regulation

2 October 2017

1 reference

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Positional cloning of the Werner's syndrome gene

2 October 2017

1 reference

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Werner's syndrome: a review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Werner's syndrome: proliferation in vitro of clones of cells bearing chromosome translocations

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Selective binding of tumor suppressor p53 protein to topologically constrained DNA: Modulation by intercalative drugs

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

The Werner syndrome helicase is a cofactor for HIV-1 long terminal repeat transactivation and retroviral replication

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Clonal structural chromosomal rearrangements in lymphocytes of four patients with Werner's syndrome

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

In vivo prooxidant state in Werner syndrome (WS): results from three WS patients and two WS heterozygotes

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Regulation of WRN helicase activity in human base excision repair

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586248

21 October 2018

Identifiers

DOI

10.1021/PR100990S

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21210717%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21210717%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

21210717

1 reference