Estrogen receptor-α recruits P-TEFb to overcome transcriptional pausing in intron 1 of the MYB gene (Q36107006)

12 August 2017

Estrogen receptor-α recruits P-TEFb to overcome transcriptional pausing in intron 1 of the MYB gene (English)

1 reference

12 August 2017

Partha Mitra

1

1 reference

12 August 2017

Lloyd A Pereira

2

1 reference

12 August 2017

Yvette Drabsch

3

1 reference

12 August 2017

Robert G Ramsay

4

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12 August 2017

Thomas J Gonda

5

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12 August 2017

language of work or name

English

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publication date

5 April 2012

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12 August 2017

13

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inferred from page(s)

published in

Nucleic Acids Research

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12 August 2017

40

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12 August 2017

13

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12 August 2017

5988-6000

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Creative Commons Attribution-NonCommercial 3.0 Unported

12 August 2017

start time

4 October 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development

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MYB is essential for mammary tumorigenesis.

2 October 2017

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An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance

2 October 2017

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Pol II waiting in the starting gates: Regulating the transition from transcription initiation into productive elongation.

2 October 2017

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MYB suppresses differentiation and apoptosis of human breast cancer cells

2 October 2017

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c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis

2 October 2017

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Progression through the RNA polymerase II CTD cycle

2 October 2017

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A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP.

2 October 2017

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ChIP-Seq of ERalpha and RNA polymerase II defines genes differentially responding to ligands

2 October 2017

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Role of the HIV-1 positive elongation factor P-TEFb and inhibitors thereof

2 October 2017

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Postrecruitment regulation of RNA polymerase II directs rapid signaling responses at the promoters of estrogen target genes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Promoter proximal pausing on genes in metazoans

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Poised RNA polymerase II gives pause for thought

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Genome-wide analysis of estrogen receptor binding sites

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Mutations in the MYB intron I regulatory sequence increase transcription in colon cancers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Controlling the elongation phase of transcription with P-TEFb

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

c-Myb and Bcl-x overexpression predicts poor prognosis in colorectal cancer: clinical and experimental findings

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Physical interaction between CDK9 and B-Myb results in suppression of B-Myb gene autoregulation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Estrogen-responsive element of the human pS2 gene is an imperfectly palindromic sequence

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Stability of Drosophila RNA polymerase II elongation complexes in vitro

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole inhibits transcription elongation by RNA polymerase II in vitro.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Fulvestrant (ICI 182,780)-dependent interacting proteins mediate immobilization and degradation of estrogen receptor-alpha

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Estrogen receptor breast cancer phenotypes in the Surveillance, Epidemiology, and End Results database.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Strong association between c-myb and oestrogen-receptor expression in human breast cancer.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401469

Differential expression of c-myb mRNA in murine B lymphomas by a block to transcription elongation

23 September 2018

1 reference

12 December 2020

Expression of c-myb protooncogene and other cell cycle-related genes in normal and neoplastic human colonic mucosa

1 reference

12 December 2020

Biological characterization and oncogene expression in human colorectal carcinoma cell lines

1 reference

12 December 2020

A transcriptional arrest mechanism involved in controlling constitutive levels of mouse c-myb mRNA

1 reference

12 December 2020

Sense and anti-sense transcription in the murine c-myb attenuator region

1 reference

12 December 2020

Microsatellite deletions in the c-myb transcriptional attenuator region associated with over-expression in colon tumour cell lines

1 reference

12 December 2020

Estrogen and MYB in breast cancer: potential for new therapies

1 reference

12 December 2020

Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKS286

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22492511

1 reference