Cleavage of Cdc6 by caspase-3 promotes ATM/ATR kinase-mediated apoptosis of HeLa cells (Q36118202)

12 August 2017

Cleavage of Cdc6 by caspase-3 promotes ATM/ATR kinase-mediated apoptosis of HeLa cells (English)

1 reference

12 August 2017

Hyungshin Yim

1

1 reference

12 August 2017

In Sun Hwang

2

1 reference

12 August 2017

Joon-Seok Choi

3

1 reference

12 August 2017

Kwang-Hoon Chun

4

1 reference

12 August 2017

Ying Hua Jin

5

1 reference

12 August 2017

Young-Mi Ham

6

1 reference

12 August 2017

Kwang Youl Lee

7

1 reference

12 August 2017

Seung Ki Lee

8

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12 August 2017

language of work or name

English

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publication date

26 June 2006

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12 August 2017

12

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inferred from page(s)

published in

Journal of Cell Biology

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12 August 2017

174

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12 August 2017

1

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12 August 2017

77-88

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DNA replication and progression through S phase

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

DNA replication defects, spontaneous DNA damage, and ATM-dependent checkpoint activation in replication protein A-deficient cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Apoptosis-like yeast cell death in response to DNA damage and replication defects

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Checkpoint responses to replication stalling: inducing tolerance and preventing mutagenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

DNA damage-triggered apoptosis: critical role of DNA repair, double-strand breaks, cell proliferation and signaling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Caspase-3-mediated Cleavage of Cdc6 Induces Nuclear Localization of p49-truncated Cdc6 and Apoptosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Apoptosis - the p53 network

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Human replication protein Cdc6 is selectively cleaved by caspase 3 during apoptosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Targeted destruction of DNA replication protein Cdc6 by cell death pathways in mammals and yeast

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Xenopus Cdc6 performs separate functions in initiating DNA replication

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Hypoxia links ATR and p53 through replication arrest

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Analysis of Cdc6 function in the assembly of mammalian prereplication complexes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Multiple mechanisms regulate subcellular localization of human CDC6.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

RGD peptides induce apoptosis by direct caspase-3 activation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

Characterization of apoptosis-induced Mcm3 and Cdc6 cleavage reveals a proapoptotic effect for one Mcm3 fragment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064166

A central role for DNA replication forks in checkpoint activation and response

2 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.200509141

Activation of budding yeast replication origins and suppression of lethal DNA damage effects on origin function by ectopic expression of the co-chaperone protein Mge1.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.200509141

Apoptosis in budding yeast caused by defects in initiation of DNA replication.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.200509141

A comparison of the activity, sequence specificity, and CRM1-dependence of different nuclear export signals

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16801388

12 December 2020

inferred from PubMed ID database lookup

Inhibiting the expression of DNA replication-initiation proteins induces apoptosis in human cancer cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16801388

12 December 2020

inferred from PubMed ID database lookup

Induction by adozelesin and hydroxyurea of origin recognition complex-dependent DNA damage and DNA replication checkpoints in Saccharomyces cerevisiae

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16801388

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1083/JCB.200509141

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

16801388

1 reference