Role of regulatory invariant CD1d-restricted natural killer T-cells in protection against type 1 diabetes (Q36124501)

12 August 2017

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title

Role of regulatory invariant CD1d-restricted natural killer T-cells in protection against type 1 diabetes (English)

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12 August 2017

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Shabbir Hussain

1

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12 August 2017

Melany Wagner

series ordinal

2

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12 August 2017

Dalam Ly

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3

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12 August 2017

Terry L Delovitch

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4

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12 August 2017

1 January 2005

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12 August 2017

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12 August 2017

31

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12 August 2017

3

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12 August 2017

177-188

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https://scigraph.springernature.com/pub.10.1385/ir:31:3:177

12 August 2017

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cites work

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12 December 2020

CD1d-Restricted NKT Cells: An Interstrain Comparison

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12 December 2020

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12 December 2020

Biolistic-mediated interleukin 4 gene transfer prevents the onset of type 1 diabetes

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12 December 2020

Low expression levels of soluble CD1d gene in patients with rheumatoid arthritis.

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12 December 2020

Up-regulation of CD1d expression restores the immunoregulatory function of NKT cells and prevents autoimmune diabetes in nonobese diabetic mice

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12 December 2020

Neonatal activation of CD28 signaling overcomes T cell anergy and prevents autoimmune diabetes by an IL-4-dependent mechanism.

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12 December 2020

beta-Cell death during progression to diabetes

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12 December 2020

NKT cell frequency in Japanese type 1 diabetes

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12 December 2020

Absolute requirement for the pre-T cell receptor alpha chain during NK1.1+ TCRalphabeta cell development.

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12 December 2020

Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes.

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12 December 2020

B cells and professional APCs recruit regulatory T cells via CCL4

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12 December 2020

Insulin-dependent diabetes mellitus

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12 December 2020

CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes

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12 December 2020

Independent genetic regulation of T-cell and antigen-presenting cell participation in autoimmune islet inflammation

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12 December 2020

A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors

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12 December 2020

NK T cell-derived IL-10 is essential for the differentiation of antigen-specific T regulatory cells in systemic tolerance

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12 December 2020

NKT cells derive from double-positive thymocytes that are positively selected by CD1d

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12 December 2020

Antitumor effect of alpha-galactosylceramide (KRN7000) on spontaneous hepatic metastases requires endogenous interleukin 12 in the liver

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12 December 2020

Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice

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12 December 2020

NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen

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12 December 2020

NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells

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12 December 2020

Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes

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12 December 2020

CD1d on antigen-transporting APC and splenic marginal zone B cells promotes NKT cell-dependent tolerance

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12 December 2020

Prevention of arthritis by interleukin 10-producing B cells

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12 December 2020

Testing the NKT cell hypothesis of human IDDM pathogenesis

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12 December 2020

A defect in bone marrow derived dendritic cell maturation in the nonobesediabetic mouse

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12 December 2020

Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity

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12 December 2020

Neonatal adaptive immunity comes of age

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12 December 2020

Systemic NKT cell deficiency in NOD mice is not detected in peripheral blood: implications for human studies

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12 December 2020

The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

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12 December 2020

Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant

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12 December 2020

Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse

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12 December 2020

Phenotypic and functional differences between NKT cells colonizing splanchnic and peripheral lymph nodes.

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12 December 2020

B cell selection defects underlie the development of diabetogenic APCs in nonobese diabetic mice

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12 December 2020

Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice.

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12 December 2020

The NKT cell system: bridging innate and acquired immunity

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12 December 2020

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

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12 December 2020

Role for IL-15/IL-15 receptor beta-chain in natural killer 1.1+ T cell receptor-alpha beta+ cell development

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12 December 2020

Association between alphabetaTCR+CD4-CD8- T-cell deficiency and IDDM in NOD/Lt mice

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12 December 2020

B lymphocyte-derived IL-16 attracts dendritic cells and Th cells

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12 December 2020

High frequency of valpha24(+) vbeta11(+) T-cells observed in type 1 diabetes

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12 December 2020

Three day neonatal thymectomy selectively depletes NK1.1+ T cells

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12 December 2020

Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors

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12 December 2020

Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

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12 December 2020

Lack of directed V alpha 14-J alpha 281 rearrangements in NK1+ T cells

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12 December 2020

Th2 bias of CD4+ NKT cells derived from multiple sclerosis in remission

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12 December 2020

NKT cell defects in NOD mice suggest therapeutic opportunities

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12 December 2020

Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets

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12 December 2020

Genetic Control of NKT Cell Numbers Maps to Major Diabetes and Lupus Loci

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12 December 2020

Ligand-dependent inhibition of CD1d-restricted NKT cell development in mice transgenic for the activating receptor Ly49D.

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12 December 2020

Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse

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12 December 2020

The NOD mouse model of type 1 diabetes: as good as it gets?

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12 December 2020

Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse

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12 December 2020

Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice.

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12 December 2020

Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes.

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12 December 2020

Function of the pre-T-cell receptor alpha chain in T-cell development and allelic exclusion at the T-cell receptor beta locus

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12 December 2020

Intrathymic NKT cell development is blocked by the presence of alpha-galactosylceramide

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12 December 2020

Regulation of autoimmune disease by natural killer T cells

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12 December 2020

Abnormal T cell selection on nod thymic epithelium is sufficient to induce autoimmune manifestations in C57BL/6 athymic nude mice

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12 December 2020

Differential expression of CC chemokines and the CCR5 receptor in the pancreas is associated with progression to type I diabetes.

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12 December 2020

The regulatory role of Valpha14 NKT cells in innate and acquired immune response.

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12 December 2020

The unconventional lifestyle of NKT cells

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12 December 2020

Mechanism of CD1d-restricted natural killer T cell activation during microbial infection.

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12 December 2020

Intrinsic defects in the T-cell lineage results in natural killer T-cell deficiency and the development of diabetes in the nonobese diabetic mouse.

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12 December 2020

CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo.

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12 December 2020

alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

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12 December 2020

A thymic precursor to the NK T cell lineage

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12 December 2020

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

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12 December 2020

Role of stromal-cell derived factor-1 in the development of autoimmune diseases in non-obese diabetic mice

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12 December 2020

NKT cells are phenotypically and functionally diverse

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12 December 2020

CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells

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12 December 2020

IL-4 prevents insulitis and insulin-dependent diabetes mellitus in nonobese diabetic mice by potentiation of regulatory T helper-2 cell function

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12 December 2020

Hyperresponsiveness, resistance to B-cell receptor-dependent activation-induced cell death, and accumulation of hyperactivated B-cells in islets is associated with the onset of insulitis but not type 1 diabetes.

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12 December 2020

The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

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12 December 2020

Reciprocal desensitization of CCR5 and CD4 is mediated by IL-16 and macrophage-inflammatory protein-1 beta, respectively

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12 December 2020

CD1d-restricted NKT regulatory cells: functional genomic analyses provide new insights into the mechanisms of protection against Type 1 diabetes

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12 December 2020

Hematopoietic stem-cell defects underlying abnormal macrophage development and maturation in NOD/Lt mice: defective regulation of cytokine receptors and protein kinase C.

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12 December 2020

Defects in the differentiation and function of bone marrow-derived dendritic cells in non-obese diabetic mice

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12 December 2020

Cutting Edge: IL-16/CD4 Preferentially Induces Th1 Cell Migration: Requirement of CCR5

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12 December 2020

Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

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12 December 2020

Qualitative and quantitative abnormalities in splenic dendritic cell populations in NOD mice.

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12 December 2020

Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice

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12 December 2020

Interleukin-4 but not interleukin-10 protects against spontaneous and recurrent type 1 diabetes by activated CD1d-restricted invariant natural killer T-cells.

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12 December 2020

Immunotherapy of NOD mice with bone marrow-derived dendritic cells

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12 December 2020

Identifiers

DOI

10.1385/IR:31:3:177

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Dimensions Publication ID

12 August 2017

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