Elevation of ω-3 Polyunsaturated Fatty Acids Attenuates PTEN-deficiency Induced Endometrial Cancer Development through Regulation of COX-2 and PGE2 Production (Q36163869)

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English	Elevation of ω-3 Polyunsaturated Fatty Acids Attenuates PTEN-deficiency Induced Endometrial Cancer Development through Regulation of COX-2 and PGE2 Production	scientific article

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scholarly article

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Europe PubMed Central

12 August 2017

Elevation of ω-3 Polyunsaturated Fatty Acids Attenuates PTEN-deficiency Induced Endometrial Cancer Development through Regulation of COX-2 and PGE2 Production (English)

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Europe PubMed Central

12 August 2017

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endometrial cancer

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based on heuristic

inferred from title

1

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4 June 2020

author name string

Lixian Cheng

2

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4 June 2020

Xinyun Bi

3

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4 June 2020

Xin Zhang

4

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4 June 2020

Shanshan Liu

5

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4 June 2020

Xiaoming Bai

6

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4 June 2020

Fanghong Li

7

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4 June 2020

Allan Z Zhao

8

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4 June 2020

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publication date

15 October 2015

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12 August 2017

Scientific Reports

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4 June 2020

5

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4 June 2020

14958

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4 June 2020

https://scigraph.springernature.com/pub.10.1038/srep14958

0 references

Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance

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2 October 2017

Prostaglandin E2 stimulates β1-integrin expression in hepatocellular carcinoma through the EP1 receptor/PKC/NF-κB pathway

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2 October 2017

Combined therapy with COX-2 inhibitor and 20-HETE inhibitor reduces colon tumor growth and the adverse effects of ischemic stroke associated with COX-2 inhibition

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2 October 2017

Inhibition of endometrial cancer by n-3 polyunsaturated fatty acids in preclinical models.

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2 October 2017

Dietary PUFA and cancer

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2 October 2017

Opposite effects of gene deficiency and pharmacological inhibition of soluble epoxide hydrolase on cardiac fibrosis

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2 October 2017

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2 October 2017

PPARα activation can help prevent and treat non-small cell lung cancer

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mTORC1/2 targeted by n-3 polyunsaturated fatty acids in the prevention of mammary tumorigenesis and tumor progression.

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Current evidence linking polyunsaturated Fatty acids with cancer risk and progression

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2 October 2017

TGF-β effects on prostate cancer cell migration and invasion are mediated by PGE2 through activation of PI3K/AKT/mTOR pathway

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2 October 2017

Omega-3 and omega-6 fatty acid intakes and endometrial cancer risk in a population-based case-control study

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Selective sensitization of tumors to chemotherapy by marine-derived lipids: a review

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The effects of the selective cyclooxygenase-2 inhibitor on endometrial cytological findings in uterine endometrial cancer patients

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2 October 2017

New insights into the health effects of dietary saturated and omega-6 and omega-3 polyunsaturated fatty acids

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2 October 2017

PGE2 promotes renal carcinoma cell invasion through activated RalA.

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2 October 2017

Contemporary management of endometrial cancer

1 reference

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2 October 2017

Critical role of arachidonic acid-activated mTOR signaling in breast carcinogenesis and angiogenesis

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2 October 2017

β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas

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2 October 2017

Acquired radioresistance of cancer and the AKT/GSK3β/cyclin D1 overexpression cycle

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2 October 2017

Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF-α

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2 October 2017

Enhanced formation of 5-oxo-6,8,11,14-eicosatetraenoic acid by cancer cells in response to oxidative stress, docosahexaenoic acid and neutrophil-derived 5-hydroxy-6,8,11,14-eicosatetraenoic acid

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Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene A₄hydrolase

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2 October 2017

Inhibition of carcinoma cell motility by epoxyeicosatrienoic acid (EET) antagonists.

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2 October 2017

Cellular production of n-3 PUFAs and reduction of n-6-to-n-3 ratios in the pancreatic beta-cells and islets enhance insulin secretion and confer protection against cytokine-induced cell death

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2 October 2017

Oocyte-specific deletion of Pten in mice reveals a stage-specific function of PTEN/PI3K signaling in oocytes in controlling follicular activation

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2 October 2017

Expression of the fat-1 gene diminishes prostate cancer growth in vivo through enhancing apoptosis and inhibiting GSK-3 beta phosphorylation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4606560

2 October 2017

Multi-targeted therapy of cancer by omega-3 fatty acids

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4606560

2 October 2017

The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases

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2 October 2017

Nox1 downstream of 12-lipoxygenase controls cell proliferation but not cell spreading of colon cancer cells

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Cyclooxygenase-2 in hepatocellular carcinoma

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4606560

2 October 2017

Mechanisms underlying the growth inhibitory effects of the cyclo-oxygenase-2 inhibitor celecoxib in human breast cancer cells

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2 October 2017

Expression of cyclooxygenase-2 in uterine endometrial cancer and anti-tumor effects of a selective COX-2 inhibitor.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4606560

2 October 2017

Cyclooxygenase-2 and its role in colorectal cancer development

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2 October 2017

Dietary long-chain n-3 fatty acids for the prevention of cancer: a review of potential mechanisms

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2 October 2017

Opposing effects of dietary n-3 and n-6 fatty acids on mammary carcinogenesis: The Singapore Chinese Health Study

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2 October 2017

Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression

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2 October 2017

DNA mismatch repair deficiency accelerates endometrial tumorigenesis in Pten heterozygous mice

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The multiple roles of PTEN in tumor suppression

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2 October 2017

Reduced colitis-associated colon cancer in Fat-1 (n-3 fatty acid desaturase) transgenic mice

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Clinical significance of tumor suppressor PTEN in colorectal carcinoma.

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23 September 2018

15-Lipoxygenases and its metabolites 15(S)-HETE and 13(S)-HODE in the development of non-small cell lung cancer

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23 September 2018

A prospective study of polyunsaturated fatty acid levels in blood and prostate cancer risk

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23 September 2018

Growth inhibitory effects of celecoxib in human umbilical vein endothelial cells are mediated through G1 arrest via multiple signaling mechanisms

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23 September 2018

Fatty fish consumption lowers the risk of endometrial cancer: a nationwide case-control study in Sweden.

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The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/- mice

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T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

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Tumor suppressor genes

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21 January 2018

Cyclooxygenase-2 expression correlates with apoptosis and angiogenesis in endometrial cancer tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/26468779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/26468779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP14958

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26468779%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26468779%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26468779%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

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