Tumor suppressor genes (Q57636194)

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Mutation and cancer: statistical study of retinoblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Mutations of mitotic checkpoint genes in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Smad3 mutant mice develop metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Lessons from hereditary colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

ONCOGENESIS: Landscaping the Cancer Terrain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Genetic instabilities in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

The complexity of p53 modulation: emerging patterns from divergent signals

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Cancer. p53, guardian of the genome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

PTEN germ-line mutations in juvenile polyposis coli

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Inherited mutations in PTEN that are associated with breast cancer, cowden disease, and juvenile polyposis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Mutations in the SMAD4/DPC4 gene in juvenile polyposis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

pRb and E2f-1 in mouse development and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Allelic imbalance, including deletion of PTEN/MMACI, at the Cowden disease locus on 10q22-23, in hamartomas from patients with Cowden syndrome and germline PTEN mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Pten is essential for embryonic development and tumour suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Impaired Fas response and autoimmunity in Pten+/- mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Loss-of-Function Mutations in PPARγ Associated with Human Colon Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

A resistant genetic background leading to incomplete penetrance of intestinal neoplasia and reduced loss of heterozygosity in ApcMin/+ mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Modeling stochastic gene expression: implications for haploinsufficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Roles for Nkx3.1 in prostate development and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Haploinsufficiency for the neurofibromatosis 1 (NF1) tumor suppressor results in increased astrocyte proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Altered neural cell fates and medulloblastoma in mouse patched mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Malignant melanoma: modern black plague and genetic black box.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

The regulation of E2F by pRB-family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Tumor surveillance via the ARF-p53 pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Apoptosis and APC in colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Differential SMN2 expression associated with SMA severity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Bax directly induces release of cytochrome c from isolated mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Direct control of the Forkhead transcription factor AFX by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Fas ligand: a sensor for DNA damage critical in skin cancer etiology

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

A matter of life and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

The caspase-RB connection in cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

RB regulates the stability and the apoptotic function of p53 via MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Traps to catch unwary oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Stabilization of beta-catenin by genetic defects in melanoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Identification of c-MYC as a target of the APC pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Signal transduction through beta-catenin and specification of cell fate during embryogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Association of the APC gene product with beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Association of the APC tumor suppressor protein with catenins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

E-cadherin germline mutations in familial gastric cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Many vessels, faulty gene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Proteolysis and the G1-S transition: the SCF connection

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Ras enhances Myc protein stability.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Critical role played by cyclin D3 in the MyoD-mediated arrest of cell cycle during myoblast differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

BRCA1 Inhibition of Estrogen Receptor Signaling in Transfected Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021

PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900041-6

7 January 2021