The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivo (Q36178061)

12 August 2017

The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivo (English)

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12 August 2017

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Michael T Buckley

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12 August 2017

Joanne Yoon

2

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12 August 2017

Herman Yee

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12 August 2017

Luis Chiriboga

4

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12 August 2017

Leonard Liebes

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12 August 2017

Gulshan Ara

6

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12 August 2017

Xiaozhong Qian

7

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12 August 2017

Dean F Bajorin

8

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12 August 2017

Tung-Tien Sun

9

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12 August 2017

Xue-Ru Wu

10

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12 August 2017

Iman Osman

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12 August 2017

language of work or name

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12 October 2007

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Journal of Translational Medicine

12 August 2017

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12 August 2017

5

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12 August 2017

49

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https://scigraph.springernature.com/pub.10.1186/1479-5876-5-49

12 August 2017

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Hyperactivation of Ha-ras oncogene, but not Ink4a/Arf deficiency, triggers bladder tumorigenesis

1 October 2017

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1 October 2017

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Hypermethylation and expression regulation of secreted frizzled-related protein genes in colorectal tumor

1 October 2017

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Toxicogenomics of endoplasmic reticulum stress inducer tunicamycin in the small intestine and liver of Nrf2 knockout and C57BL/6J mice

1 October 2017

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The histone deacetylase inhibitor PXD101 synergises with 5-fluorouracil to inhibit colon cancer cell growth in vitro and in vivo.

1 October 2017

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Valproic acid, a histone deacetylase inhibitor, is an antagonist for oncolytic adenoviral gene therapy

1 October 2017

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Activity of PXD101, a histone deacetylase inhibitor, in preclinical ovarian cancer studies

1 October 2017

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Valproic acid inhibits invasiveness in bladder cancer but not in prostate cancer cells

1 October 2017

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Identification of Nrf2-regulated genes induced by chemopreventive isothiocyanate PEITC by oligonucleotide microarray

1 October 2017

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Histone deacetylase inhibitor trichostatin A inhibits the growth of bladder cancer cells through induction of p21WAF1 and G1 cell cycle arrest

1 October 2017

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Quantitative proteomic analysis of post-translational modifications of human histones

1 October 2017

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Histone deacetylase inhibitors modulate the sensitivity of tumor necrosis factor-related apoptosis-inducing ligand-resistant bladder tumor cells

1 October 2017

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Proteasome inhibition with bortezomib (PS-341): a phase I study with pharmacodynamic end points using a day 1 and day 4 schedule in a 14-day cycle

1 October 2017

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Urothelial tumorigenesis: a tale of divergent pathways

1 October 2017

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Review: tubulin function, action of antitubulin drugs, and new drug development

1 October 2017

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Recombinant alpha2(IV)NC1 domain inhibits tumor cell-extracellular matrix interactions, induces cellular senescence, and inhibits tumor growth in vivo

1 October 2017

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Cell growth inhibition and gene expression induced by the histone deacetylase inhibitor, trichostatin A, on human hepatoma cells

1 October 2017

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1 October 2017

Cancer statistics, 2004

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Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1

1 October 2017

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P21(WAF1/CIP1) is dispensable for G1 arrest, but indispensable for apoptosis induced by sodium butyrate in MCF-7 breast cancer cells.

1 October 2017

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Histone deacetylase inhibitors induce growth suppression and cell death in human rhabdomyosarcoma in vitro.

1 October 2017

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Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid administered intravenously.

1 October 2017

1 reference

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Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2100044

Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure

1 October 2017

1 reference

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Histone deacetylase inhibitors such as sodium butyrate and trichostatin A induce apoptosis through an increase of the bcl-2-related protein Bad.

1 October 2017

1 reference

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Histone deacetylases and cancer: causes and therapies

1 October 2017

1 reference

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Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms

1 October 2017

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Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

1 October 2017

1 reference

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Histone deacetylase inhibitor activates the p21/WAF1/Cip1 gene promoter through the Sp1 sites

1 October 2017

1 reference

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Evaluation of asymptomatic microscopic hematuria

1 October 2017

1 reference

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SARPs: a family of secreted apoptosis-related proteins

1 October 2017

1 reference

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Selective interactions of UPIa and UPIb, two members of the transmembrane 4 superfamily, with distinct single transmembrane-domained proteins in differentiated urothelial cells

1 October 2017

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Suppression of adiponectin gene expression by histone deacetylase inhibitor valproic acid

1 October 2017

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Concurrent mutations of coding and regulatory sequences of the Ha-ras gene in urinary bladder carcinomas

2 July 2018

1 reference

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Early detection and measurement of urothelial tumors in mice.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2100044

Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2100044

A Phase I clinical and pharmacological evaluation of sodium phenylbutyrate on an 120-h infusion schedule

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2100044

Identification of H-ras mutations in urine sediments complements cytology in the detection of bladder tumors

23 September 2018

1 reference

12 December 2020

Urothelium-specific expression of an oncogene in transgenic mice induced the formation of carcinoma in situ and invasive transitional cell carcinoma

1 reference

12 December 2020

Prostate cancer cell cycle regulators: response to androgen withdrawal and development of androgen independence

1 reference

12 December 2020

Gender differences in stage-adjusted bladder cancer survival

1 reference

12 December 2020

Uroplakin and androgen receptor expression in the human fetal genital tract: insights into the development of the vagina

1 reference

12 December 2020

Role of Ha-ras activation in superficial papillary pathway of urothelial tumor formation

1 reference

12 December 2020

Molecular profiling of bladder cancer using cDNA microarrays: defining histogenesis and biological phenotypes

1 reference

12 December 2020

Identifiers

DOI

10.1186/1479-5876-5-49

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Dimensions Publication ID

12 August 2017

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12 August 2017

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