Specific molecular signatures predict decitabine response in chronic myelomonocytic leukemia. (Q36179524)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25822018%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Specific molecular signatures predict decitabine response in chronic myelomonocytic leukemia (English)

1 reference

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4

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4 March 2020

Dorothée Selimoglu-Buet

7

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4 March 2020

Eric Solary

13

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4 March 2020

Valeria Santini

15

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4 March 2020

Maria E Figueroa

16

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4 March 2020

1

Kristen Meldi

1 reference

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4 March 2020

2

Tingting Qin

1 reference

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4 March 2020

6

Jean-Baptiste Micol

1 reference

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4 March 2020

author name string

Francesca Buchi

3

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4 March 2020

Jason Sotzen

5

1 reference

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4 March 2020

Erico Masala

8

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4 March 2020

Bernardino Allione

9

1 reference

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4 March 2020

Daniela Gioia

10

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4 March 2020

Antonella Poloni

11

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4 March 2020

Monia Lunghi

12

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4 March 2020

Omar Abdel-Wahab

14

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4 March 2020

language of work or name

English

0 references

publication date

30 March 2015

1 reference

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Journal of Clinical Investigation

4 March 2020

published in

1 reference

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4 March 2020

volume

125

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4 March 2020

page(s)

1857-1872

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4 March 2020

issue

5

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Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion.

4 March 2020

cites work

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BRAF kinase domain mutations are present in a subset of chronic myelomonocytic leukemia with wild-type RAS.

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The possible diagnostic and prognostic use of systemic chemokine profiles in clinical medicine—the experience in acute myeloid leukemia from disease development and diagnosis via conventional chemotherapy to allogeneic stem cell transplantation

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1 October 2017

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The long-range interaction landscape of gene promoters

1 October 2017

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SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

1 October 2017

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Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia

1 October 2017

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Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells

1 October 2017

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Constitutive MAP kinase activation in hematopoietic stem cells induces a myeloproliferative disorder

1 October 2017

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Frequent pathway mutations of splicing machinery in myelodysplasia

1 October 2017

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Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A.

1 October 2017

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1 October 2017

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Outcome of high-risk myelodysplastic syndrome after azacitidine treatment failure

1 October 2017

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Clinical effect of point mutations in myelodysplastic syndromes

1 October 2017

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A framework for variation discovery and genotyping using next-generation DNA sequencing data

1 October 2017

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Recurrent DNMT3A mutations in patients with myelodysplastic syndromes

1 October 2017

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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

1 October 2017

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Identification of disease- and therapy-associated proteome changes in the sera of patients with myelodysplastic syndromes and del(5q).

1 October 2017

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Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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The chemokine network in acute myelogenous leukemia: molecular mechanisms involved in leukemogenesis and therapeutic implications

1 October 2017

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Dominant roles of the Raf/MEK/ERK pathway in cell cycle progression, prevention of apoptosis and sensitivity to chemotherapeutic drugs

1 October 2017

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Targeting of 5-aza-2'-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme

1 October 2017

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DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes

1 October 2017

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Quantitative DNA methylation predicts survival in adult acute myeloid leukemia

1 October 2017

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Comprehensive mapping of long-range interactions reveals folding principles of the human genome

1 October 2017

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Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS.

1 October 2017

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TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia

1 October 2017

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MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

1 October 2017

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Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.

1 October 2017

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Fast and accurate short read alignment with Burrows-Wheeler transform

1 October 2017

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1 October 2017

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Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML.

1 October 2017

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Aberrant DNA methylation is a dominant mechanism in MDS progression to AML.

1 October 2017

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DNA methyltransferase and histone deacetylase inhibitors in the treatment of myelodysplastic syndromes

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Effects of 5-azacytidine on hepatic polyribosomes and maturation of ribosomal RNA.

1 October 2017

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1 October 2017

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2 July 2018

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2 July 2018

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2 July 2018

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Prognostic score including gene mutations in chronic myelomonocytic leukemia.

2 July 2018

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Multiple mechanisms deregulate EZH2 and histone H3 lysine 27 epigenetic changes in myeloid malignancies.

23 September 2018

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Spliceosome mutations involving SRSF2, SF3B1, and U2AF35 in chronic myelomonocytic leukemia: prevalence, clinical correlates, and prognostic relevance.

23 September 2018

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Molecular predictors of response to decitabine in advanced chronic myelomonocytic leukemia: a phase 2 trial.

23 September 2018

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Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine.

23 September 2018

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Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia.

23 September 2018

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Transcriptional analysis of quiescent and proliferating CD34+ human hemopoietic cells from normal and chronic myeloid leukemia sources.

23 September 2018

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Role of the p38 mitogen-activated protein kinase pathway in cytokine-mediated hematopoietic suppression in myelodysplastic syndromes

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611703

Characterization of DNA demethylation effects induced by 5-Aza-2'-deoxycytidine in patients with myelodysplastic syndrome.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611703

Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611703

Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611703

HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611703

Next-Generation Sequencing Technology Reveals a Characteristic Pattern of Molecular Mutations in 72.8% of Chronic Myelomonocytic Leukemia by Detecting Frequent Alterations in TET2, CBL, RAS, and RUNX1

5 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611703

Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia

5 December 2018

1 reference

12 December 2020

Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms

1 reference

12 December 2020

Novel homo- and hemizygous mutations in EZH2 in myeloid malignancies

1 reference

12 December 2020

Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias

1 reference

12 December 2020

Impact of molecular mutations on treatment response to DNMT inhibitors in myelodysplasia and related neoplasms

1 reference

12 December 2020

Platelet factor 4 promotes adhesion of hematopoietic progenitor cells and binds IL-8: novel mechanisms for modulation of hematopoiesis

1 reference

12 December 2020

Platelet factor 4 and other CXC chemokines support the survival of normal hematopoietic cells and reduce the chemosensitivity of cells to cytotoxic agents

1 reference

12 December 2020

Regulated expression of platelet factor 4 in human monocytes--role of PARs as a quantitatively important monocyte activation pathway

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI78752

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25822018%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25822018%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference